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Clinical Characteristics and Outcome of Acute Heart Failure in Korea: Results from the Korean Acute Heart Failure Registry (KorAHF).

Abstract The burden of heart failure has increased in Korea. This registry aims to evaluate demographics, clinical characteristics, management, and long-term outcomes in patients hospitalized for acute heart failure (AHF).
PMID
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Authors

Mayor MeshTerms
Keywords

Guideline adherence

Heart failure, acute heart failure

Mortality

Quality of health care

Treatment outcome

Journal Title korean circulation journal
Publication Year Start




PMID- 28567084
OWN - NLM
STAT- PubMed-not-MEDLINE
DA  - 20170601
LR  - 20170816
IS  - 1738-5520 (Print)
IS  - 1738-5520 (Linking)
VI  - 47
IP  - 3
DP  - 2017 May
TI  - Clinical Characteristics and Outcome of Acute Heart Failure in Korea: Results
      from the Korean Acute Heart Failure Registry (KorAHF).
PG  - 341-353
LID - 10.4070/kcj.2016.0419 [doi]
AB  - BACKGROUND AND OBJECTIVES: The burden of heart failure has increased in Korea.
      This registry aims to evaluate demographics, clinical characteristics,
      management, and long-term outcomes in patients hospitalized for acute heart
      failure (AHF). SUBJECTS AND METHODS: We prospectively enrolled a total of 5625
      consecutive subjects hospitalized for AHF in one of 10 tertiary university
      hospitals from March 2011 to February 2014. Descriptive statistics were used to
      determine the baseline characteristics of the study population and to compare
      them with those from other registries. RESULTS: The mean age was 68.5+/-14.5
      years, 53.2% were male, and 52.2% had de novo heart failure. The mean systolic
      and diastolic blood pressures were 131.2+/-30.3 mmHg and 78.6+/-18.8 mmHg at
      admission, respectively. The left ventricular ejection fraction was </=40% in
      60.5% of patients. Ischemia was the most frequent etiology (37.6%) and
      aggravating factor (26.3%). Angiotensin converting enzyme inhibitors/angiotensin 
      receptor blockers, beta-blockers, and aldosterone antagonists were prescribed in 
      68.8%, 52.2%, and 46.6% of the patients at discharge, respectively. Compared with
      the previous registry performed in Korea a decade ago, extracorporeal membrane
      oxygenation (ECMO) and heart transplantation have been performed more frequently 
      (ECMO 0.8% vs. 2.8%, heart transplantation 0.3% vs. 1.2%), and in-hospital
      mortality decreased from 7.6% to 4.8%. However, the total cost of hospital care
      increased by 40%, and one-year follow-up mortality remained high. CONCLUSION:
      While the quality of acute clinical care and AHF-related outcomes have improved
      over the last decade, the long-term prognosis of heart failure is still poor in
      Korea. Therefore, additional research is needed to improve long-term outcomes and
      implement cost-effective care.
FAU - Lee, Sang Eun
AU  - Lee SE
AD  - Department of Internal Medicine, Seoul National University Hospital, Seoul,
      Korea.
FAU - Lee, Hae-Young
AU  - Lee HY
AD  - Department of Internal Medicine, Seoul National University Hospital, Seoul,
      Korea.
FAU - Cho, Hyun-Jai
AU  - Cho HJ
AD  - Department of Internal Medicine, Seoul National University Hospital, Seoul,
      Korea.
FAU - Choe, Won-Seok
AU  - Choe WS
AD  - Department of Internal Medicine, Seoul National University Hospital, Seoul,
      Korea.
FAU - Kim, Hokon
AU  - Kim H
AD  - Department of Internal Medicine, Seoul National University Hospital, Seoul,
      Korea.
FAU - Choi, Jin Oh
AU  - Choi JO
AD  - Department of Internal Medicine, Sungkyunkwan University College of Medicine,
      Seoul, Korea.
FAU - Jeon, Eun-Seok
AU  - Jeon ES
AD  - Department of Internal Medicine, Sungkyunkwan University College of Medicine,
      Seoul, Korea.
FAU - Kim, Min-Seok
AU  - Kim MS
AD  - Department of Internal Medicine, Asan Medical Center, University of Ulsan College
      of Medicine, Seoul, Korea.
FAU - Kim, Jae-Joong
AU  - Kim JJ
AD  - Department of Internal Medicine, Asan Medical Center, University of Ulsan College
      of Medicine, Seoul, Korea.
FAU - Hwang, Kyung-Kuk
AU  - Hwang KK
AD  - Department of Internal Medicine, Chungbuk National University College of
      Medicine, Cheongju, Korea.
FAU - Chae, Shung Chull
AU  - Chae SC
AD  - Department of Internal Medicine, Kyungpook National University College of
      Medicine, Daegu, Korea.
FAU - Baek, Sang Hong
AU  - Baek SH
AD  - Department of Internal Medicine, College of Medicine, The Catholic University of 
      Korea, Seoul, Korea.
FAU - Kang, Seok-Min
AU  - Kang SM
AD  - Department of Internal Medicine, Yonsei University College of Medicine, Seoul,
      Korea.
FAU - Choi, Dong-Ju
AU  - Choi DJ
AD  - Department of Internal Medicine, Seoul National University Bundang Hospital,
      Seongnam, Korea.
FAU - Yoo, Byung-Su
AU  - Yoo BS
AD  - Department of Internal Medicine, Yonsei University Wonju College of Medicine,
      Wonju, Korea.
FAU - Kim, Kye Hun
AU  - Kim KH
AD  - Department of Internal Medicine, Heart Research Center of Chonnam National
      University, Gwangju, Korea.
FAU - Park, Hyun-Young
AU  - Park HY
AD  - Division of Cardiovascular and Rare Diseases, Korea National Institute of Health,
      Cheongju, Korea.
FAU - Cho, Myeong-Chan
AU  - Cho MC
AD  - Department of Internal Medicine, Chungbuk National University College of
      Medicine, Cheongju, Korea.
FAU - Oh, Byung-Hee
AU  - Oh BH
AD  - Department of Internal Medicine, Seoul National University Hospital, Seoul,
      Korea.
LA  - eng
PT  - Journal Article
DEP - 20170525
PL  - Korea (South)
TA  - Korean Circ J
JT  - Korean circulation journal
JID - 101247141
PMC - PMC5449528
OTO - NOTNLM
OT  - Guideline adherence
OT  - Heart failure, acute heart failure
OT  - Mortality
OT  - Quality of health care
OT  - Treatment outcome
COI - The authors have no financial conflicts of interest.
EDAT- 2017/06/02 06:00
MHDA- 2017/06/02 06:01
CRDT- 2017/06/02 06:00
PHST- 2016/11/28 [received]
PHST- 2017/02/03 [revised]
PHST- 2017/02/07 [accepted]
AID - 10.4070/kcj.2016.0419 [doi]
PST - ppublish
SO  - Korean Circ J. 2017 May;47(3):341-353. doi: 10.4070/kcj.2016.0419. Epub 2017 May 
      25.