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Imaging diagnosis of orbital Wegener granulomatosis: A rare case report.

Abstract Wegener granulomatosis (WG) is a rare idiopathic autoimmune disease causing necrotizing granulomatous vasculitis. Whether as the first symptom or as part of systemic changes, ocular manifestations in WG patients are not specific. Any part of the eyes can be affected, with the anterior segment and orbit most commonly involved. So, early diagnosis and treatment are essential for controlling the progression of the disease and improving the quality of life for patients.
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Journal Title medicine
Publication Year Start




PMID- 28591026
OWN - NLM
STAT- In-Process
DA  - 20170607
LR  - 20170607
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 23
DP  - 2017 Jun
TI  - Imaging diagnosis of orbital Wegener granulomatosis: A rare case report.
PG  - e6904
LID - 10.1097/MD.0000000000006904 [doi]
AB  - INTRODUCTION: Wegener granulomatosis (WG) is a rare idiopathic autoimmune disease
      causing necrotizing granulomatous vasculitis. Whether as the first symptom or as 
      part of systemic changes, ocular manifestations in WG patients are not specific. 
      Any part of the eyes can be affected, with the anterior segment and orbit most
      commonly involved. So, early diagnosis and treatment are essential for
      controlling the progression of the disease and improving the quality of life for 
      patients. CLINICAL FINDINGS/PATIENT CONCERNS: Here we present a rare case of
      orbital WG of a 22-year-old woman was admitted to the hospital because of intense
      pain associated with decreased visual acuity in her right eye since 1 day. She
      had been previously diagnosed with WG at our hospital. IMAGING DIAGNOSIS: Orbital
      computed tomography imaging showed diffuse swelling of intraorbital muscles, and 
      space-occupying lesions were present in both eyes. Most postnasal anatomical
      structures were absent, appearing as a massive cavity shadow. Orbital magnetic
      resonance imaging showed a shadow of orbital soft tissues. CONCLUSION: WG is a
      serious, fatal disease. Early diagnosis and treatment are essential for
      controlling the progression of the disease and improving the quality of life for 
      patients.
FAU - Yang, Bin
AU  - Yang B
AD  - aDepartment of Radiology, The First Affiliated Hospital of Kunming Medical
      University, Kunming bDepartment of Radiology, The First Affiliated Hospital of
      Dali University, Dali cDepartment of Ophthalmology, The First Affiliated Hospital
      of Dali University, Dali, China.
FAU - Yin, Zhijian
AU  - Yin Z
FAU - Chen, Shuai
AU  - Chen S
FAU - Yuan, Feng
AU  - Yuan F
FAU - Zhao, Wei
AU  - Zhao W
FAU - Yang, Yaying
AU  - Yang Y
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
EDAT- 2017/06/08 06:00
MHDA- 2017/06/08 06:00
CRDT- 2017/06/08 06:00
AID - 10.1097/MD.0000000000006904 [doi]
AID - 00005792-201706090-00002 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Jun;96(23):e6904. doi: 10.1097/MD.0000000000006904.

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