PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Association between red blood cell distribution width and Henoch-Schonlein purpura nephritis.

Abstract To investigate whether red blood cell distribution width (RDW) is a marker of the risk of Henoch-Schonlein purpura (HSP) nephritis (HSPN), a total of 669 HSP patients and 168 healthy controls were included in this retrospective study. Two hundred fifty-six (38.3%) of the patients had kidney involvement. Compared with the HSP group, RDW was significantly higher in the HSPN group (P < .001). Binary logistic regression identified that HSPN was independently associated with age, RDW, platelet, and total cholesterol (odds ratio = 1.409, 1.353, 0.996, and 2.019, respectively). In addition, RDW values of HSPN patients with crescents on histopathology (classes III, IV, and V) were higher compared with those of HSPN without crescents (classes I and II) (P = .019). The receiver-operating characteristic curve analysis showed that the RDW at a cut-off point of 13.25 has 61% sensitivity and 79% specificity in predicting the presence of crescents on histopathology. It was first shown that RDW levels in HSPN are significantly higher than those in HSP without nephritis and healthy controls. RDW can be an independent predictor of HSPN and its levels greater than 13.25 were useful in the predicting the presence of crescents on histopathology.
PMID
Related Publications

Association of endothelial nitric oxide synthase gene polymorphism with the risk of Henoch-Schönlein purpura/Henoch-Schönlein purpura nephritis.

Circulating midkine in children with Henoch-Schönlein purpura: Clinical implications.

Pentraxin 3 as a novel early biomarker for the prediction of Henoch-Schönlein purpura nephritis in children.

Clinico-pathological association of Henoch-Schoenlein purpura nephritis and IgA nephropathy in children.

Clinical significance of serum levels of IGF-1 and IGFBP-3 in children with Henoch-Schonlein purpura or Henoch-Schonlein purpura nephritis.

Authors

Mayor MeshTerms

Erythrocyte Indices

Keywords
Journal Title medicine
Publication Year Start




PMID- 28591051
OWN - NLM
STAT- MEDLINE
DA  - 20170607
DCOM- 20170706
LR  - 20170706
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 23
DP  - 2017 Jun
TI  - Association between red blood cell distribution width and Henoch-Schonlein
      purpura nephritis.
PG  - e7091
LID - 10.1097/MD.0000000000007091 [doi]
AB  - To investigate whether red blood cell distribution width (RDW) is a marker of the
      risk of Henoch-Schonlein purpura (HSP) nephritis (HSPN), a total of 669 HSP
      patients and 168 healthy controls were included in this retrospective study. Two 
      hundred fifty-six (38.3%) of the patients had kidney involvement. Compared with
      the HSP group, RDW was significantly higher in the HSPN group (P &lt; .001). Binary 
      logistic regression identified that HSPN was independently associated with age,
      RDW, platelet, and total cholesterol (odds ratio = 1.409, 1.353, 0.996, and
      2.019, respectively). In addition, RDW values of HSPN patients with crescents on 
      histopathology (classes III, IV, and V) were higher compared with those of HSPN
      without crescents (classes I and II) (P = .019). The receiver-operating
      characteristic curve analysis showed that the RDW at a cut-off point of 13.25 has
      61% sensitivity and 79% specificity in predicting the presence of crescents on
      histopathology. It was first shown that RDW levels in HSPN are significantly
      higher than those in HSP without nephritis and healthy controls. RDW can be an
      independent predictor of HSPN and its levels greater than 13.25 were useful in
      the predicting the presence of crescents on histopathology.
FAU - Xu, Hui
AU  - Xu H
AD  - aDepartment of Clinical Laboratory bDepartment of Nephrology, Children's Hospital
      of Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
FAU - Li, Wei
AU  - Li W
FAU - Mao, Jian-Hua
AU  - Mao JH
FAU - Pan, Yan-Xiang
AU  - Pan YX
LA  - eng
PT  - Journal Article
PT  - Observational Study
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Biomarkers)
RN  - 97C5T2UQ7J (Cholesterol)
SB  - AIM
SB  - IM
MH  - Age Factors
MH  - Biomarkers/blood
MH  - Child
MH  - Cholesterol/blood
MH  - *Erythrocyte Indices
MH  - Erythrocytes/pathology
MH  - Female
MH  - Humans
MH  - Logistic Models
MH  - Male
MH  - Multivariate Analysis
MH  - Nephritis/*blood
MH  - Odds Ratio
MH  - Prognosis
MH  - Purpura, Schoenlein-Henoch/*blood
MH  - ROC Curve
MH  - Retrospective Studies
MH  - Risk
PMC - PMC5466229
EDAT- 2017/06/08 06:00
MHDA- 2017/07/07 06:00
CRDT- 2017/06/08 06:00
AID - 10.1097/MD.0000000000007091 [doi]
AID - 00005792-201706090-00027 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Jun;96(23):e7091. doi: 10.1097/MD.0000000000007091.