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Sarcoid-like cutaneous lesions in chronic adult paracoccidioidomycosis: report of two cases.

Abstract This study reports two cases of chronic paracoccidioidomycosis with sarcoid-like cutaneous lesions. The patients began the treatment in 2013 at Hospital Universitário Clementino Fraga Filho (HUCFF) of the Universidade Federal do Rio de Janeiro (UFRJ). The first case (mild form) was treated with trimethoprim-sulfamethoxazole (8 mg /kg per day, orally) for three months and, then, with half the dose for nine months; the second (moderate form), with itraconazole (200 mg per day, orally) for 12 months. We point out the rareness of the sarcoid-like cutaneous lesions and the differential diagnoses for other granulomatous diseases.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title revista do instituto de medicina tropical de sao paulo
Publication Year Start




PMID- 28591264
OWN - NLM
STAT- MEDLINE
DA  - 20170607
DCOM- 20170705
LR  - 20170705
IS  - 1678-9946 (Electronic)
IS  - 0036-4665 (Linking)
VI  - 59
DP  - 2017 Jun 01
TI  - Sarcoid-like cutaneous lesions in chronic adult paracoccidioidomycosis: report of
      two cases.
PG  - e36
LID - S0036-46652017005000405 [pii]
LID - 10.1590/S1678-9946201759036 [doi]
AB  - This study reports two cases of chronic paracoccidioidomycosis with sarcoid-like 
      cutaneous lesions. The patients began the treatment in 2013 at Hospital
      Universitario Clementino Fraga Filho (HUCFF) of the Universidade Federal do Rio
      de Janeiro (UFRJ). The first case (mild form) was treated with
      trimethoprim-sulfamethoxazole (8 mg /kg per day, orally) for three months and,
      then, with half the dose for nine months; the second (moderate form), with
      itraconazole (200 mg per day, orally) for 12 months. We point out the rareness of
      the sarcoid-like cutaneous lesions and the differential diagnoses for other
      granulomatous diseases.
FAU - Fernandes, Nurimar C
AU  - Fernandes NC
AD  - Universidade Federal do Rio de Janeiro, Hospital Universitario Clementino Fraga
      Filho, Servico de Dermatologia, Rio de Janeiro, Rio de Janeiro, Brazil.
FAU - Cortes, Julia Gomes
AU  - Cortes JG
AD  - Universidade Federal do Rio de Janeiro, Hospital Universitario Clementino Fraga
      Filho, Curso de Especializacao em Dermatologia, Rio de Janeiro, Rio de Janeiro,
      Brazil.
FAU - Akitti, Tiyomi
AU  - Akitti T
AD  - Universidade Federal do Rio de Janeiro, Hospital Universitario Clementino Fraga
      Filho, Laboratorio de Micologia, Rio de Janeiro, Rio de Janeiro, Brazil.
FAU - Quintella, Danielle Carvalho
AU  - Quintella DC
AD  - Universidade Federal do Rio de Janeiro, Hospital Universitario Clementino Fraga
      Filho, Departamento de Patologia, Rio de Janeiro, Rio de Janeiro, Brazil.
FAU - Cuzzi, Tulia
AU  - Cuzzi T
AD  - Universidade Federal do Rio de Janeiro, Hospital Universitario Clementino Fraga
      Filho, Servico de Dermatologia, Rio de Janeiro, Rio de Janeiro, Brazil.
AD  - Instituto de Pesquisa Clinica Evandro Chagas, FIOCRUZ, Rio de Janeiro, Rio de
      Janeiro, Brazil.
LA  - eng
PT  - Case Reports
DEP - 20170601
PL  - Brazil
TA  - Rev Inst Med Trop Sao Paulo
JT  - Revista do Instituto de Medicina Tropical de Sao Paulo
JID - 7507484
RN  - 0 (Antifungal Agents)
RN  - 304NUG5GF4 (Itraconazole)
RN  - 8064-90-2 (Trimethoprim, Sulfamethoxazole Drug Combination)
SB  - IM
MH  - Antifungal Agents/therapeutic use
MH  - Chronic Disease
MH  - Humans
MH  - Itraconazole/therapeutic use
MH  - Male
MH  - Middle Aged
MH  - Paracoccidioidomycosis/*complications/drug therapy/pathology
MH  - Sarcoidosis/*complications/pathology
MH  - Severity of Illness Index
MH  - Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use
PMC - PMC5459543
EDAT- 2017/06/08 06:00
MHDA- 2017/07/06 06:00
CRDT- 2017/06/08 06:00
PHST- 2016/09/23 [received]
PHST- 2017/02/22 [accepted]
AID - S0036-46652017005000405 [pii]
AID - 10.1590/S1678-9946201759036 [doi]
PST - epublish
SO  - Rev Inst Med Trop Sao Paulo. 2017 Jun 1;59:e36. doi: 10.1590/S1678-9946201759036.