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Utilization of ring-shaped bone allograft for surgical treatment of adolescent post-tubercular kyphosis: A retrospective study.

Abstract This study aimed to investigate the mid-term outcome of ring-shaped bone allografts in the surgical treatment of adolescent post-tubercular kyphosis secondary to spinal tuberculosis.The records of adolescent patients diagnosed with spinal tuberculosis who received treatment in our department between 2009 and 2013 were retrospectively reviewed. The anterior approach was used in cases of cervical kyphosis and the posterior approach was used in cases of thoracic and lumbar kyphosis. During the surgery, the ring-shaped bone was used as a structural bone graft associated with the cancellous bone filing in the center portion of the ring shape. Cobb's angle, signs of spinal infusion on computed tomography, and complications were followed up.A total of 25 patients were included in our study. Among them, 3 involved the cervical region, 5 involved the thoracic region, 8 involved the thoracolumbar region, and 9 involved the lumbar region. The preoperative kyphosis deformity was a mean 65° Cobb's angle (40°-97°) compared to the postoperative 14° Cobb's angle (10°-21°) for an average correction of 51°. All wounds healed well without graft rejection. All patients achieved bone fusion 3 months postoperative for a 100% fusion rate.Our results show that the ring-shaped allograft bone is an effective option for the treatment of adolescent kyphosis. The ring-shaped allograft bone demonstrated satisfactory mechanical strength and vertebral fusion without mid-term metallic toxicity.
PMID
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Authors

Mayor MeshTerms

Spinal Fusion

Keywords
Journal Title medicine
Publication Year Start




PMID- 28614236
OWN - NLM
STAT- MEDLINE
DA  - 20170614
DCOM- 20170706
LR  - 20170706
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 24
DP  - 2017 Jun
TI  - Utilization of ring-shaped bone allograft for surgical treatment of adolescent
      post-tubercular kyphosis: A retrospective study.
PG  - e7132
LID - 10.1097/MD.0000000000007132 [doi]
AB  - This study aimed to investigate the mid-term outcome of ring-shaped bone
      allografts in the surgical treatment of adolescent post-tubercular kyphosis
      secondary to spinal tuberculosis.The records of adolescent patients diagnosed
      with spinal tuberculosis who received treatment in our department between 2009
      and 2013 were retrospectively reviewed. The anterior approach was used in cases
      of cervical kyphosis and the posterior approach was used in cases of thoracic and
      lumbar kyphosis. During the surgery, the ring-shaped bone was used as a
      structural bone graft associated with the cancellous bone filing in the center
      portion of the ring shape. Cobb's angle, signs of spinal infusion on computed
      tomography, and complications were followed up.A total of 25 patients were
      included in our study. Among them, 3 involved the cervical region, 5 involved the
      thoracic region, 8 involved the thoracolumbar region, and 9 involved the lumbar
      region. The preoperative kyphosis deformity was a mean 65 degrees Cobb's angle
      (40 degrees -97 degrees ) compared to the postoperative 14 degrees Cobb's angle
      (10 degrees -21 degrees ) for an average correction of 51 degrees . All wounds
      healed well without graft rejection. All patients achieved bone fusion 3 months
      postoperative for a 100% fusion rate.Our results show that the ring-shaped
      allograft bone is an effective option for the treatment of adolescent kyphosis.
      The ring-shaped allograft bone demonstrated satisfactory mechanical strength and 
      vertebral fusion without mid-term metallic toxicity.
FAU - Yin, Xiang
AU  - Yin X
AD  - Department of Spinal Surgery, Institute of Surgery Research, Daping Hospital,
      Third Military Medical University, Chongqing, China.
FAU - Liu, Peng
AU  - Liu P
FAU - Liu, Yao-Yao
AU  - Liu YY
FAU - Fan, Wei-Li
AU  - Fan WL
FAU - Liu, Bai-Yi
AU  - Liu BY
FAU - Zhao, Jian-Hua
AU  - Zhao JH
LA  - eng
PT  - Journal Article
PT  - Observational Study
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - AIM
SB  - IM
MH  - Adolescent
MH  - Bone Transplantation/methods/*utilization
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Kyphosis/diagnostic imaging/*etiology/*surgery
MH  - Male
MH  - Retrospective Studies
MH  - *Spinal Fusion/methods
MH  - Treatment Outcome
MH  - Tuberculosis, Spinal/*complications/diagnostic imaging/surgery
EDAT- 2017/06/15 06:00
MHDA- 2017/07/07 06:00
CRDT- 2017/06/15 06:00
AID - 10.1097/MD.0000000000007132 [doi]
AID - 00005792-201706160-00022 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Jun;96(24):e7132. doi: 10.1097/MD.0000000000007132.