A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

PMID- 28614253
DA  - 20170614
DCOM- 20170706
LR  - 20170706
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 24
DP  - 2017 Jun
TI  - A systematic review and meta-analysis into the effect of lateral wedge arch
      support insoles for reducing knee joint load in patients with medial knee
PG  - e7168
LID - 10.1097/MD.0000000000007168 [doi]
AB  - OBJECTIVE: The aim of this study was to evaluate the immediate effects of lateral
      wedge arch support insoles (LWAS) on reducing the knee joint load in patients
      with medial knee osteoarthritis (OA) compared with an appropriate control.
      METHODS: Databases including Medline, EMBASE, Web of Science, Wiley Online
      Library, Cochrane library, and Google Scholar were searched with no limits on
      study date or language, from the earliest available date to October 31, 2016. The
      included studies had to have the aim of reducing knee load and have an
      appropriate control. The main measured values were the first and second peak
      external knee adduction moments (EKAM) and the knee adduction angular impulse
      (KAAI). The random-effects model was used for analyzing the eligible studies.
      RESULTS: Nine studies met the inclusion criteria with a total of 356 participants
      of whom 337 received LWAS treatment. The risk of methodological bias scores
      (quality index) ranged from 21 to 27 of 32. Treatment with LWAS resulted in
      statistically significant reductions in the first peak EKAM (P = .005), the
      second peak EKAM (P = .01), and the KAAI (P = .03). However, among trials in
      which the control treatment was control shoes, the LWAS showed no associations on
      the first peak EKAM (P = .10) or the KAAI (P = .06); among trials in which the
      control treatment was neutral insoles, the LWAS showed no associations on the
      second peak EKAM (P = .21) or the KAAI (P = .23). At the same time, the LWAS
      showed no statistically significant reduction on the first peak EKAM (P = .39)
      when compared with flat insoles. CONCLUSION: Although meta-analysis outcomes of
      all studies indicated statistically significant associations between LWAS and
      reductions of the first peak EKAM, second peak EKAM and KAAI in people with
      medial knee OA while walking, different results existed in subgroups using
      various control conditions for comparison. These findings do not support the use 
      of LWAS insoles for reducing knee load. An optimal LWAS treatment should provide 
      the appropriate height of arch support and amount of lateral wedging. Further
      research should investigate the best combination of these 2 parameters to achieve
      efficacy without altered comfort.
FAU - Xing, Fei
AU  - Xing F
AD  - aBiomechanics Labs of Orthopedics Institute, Tianjin Hospital bTianjin Medical
      University cDepartment of Orthopedics, Tianjin Hospital, Tianjin, People's
      Republic of China.
FAU - Lu, Bin
AU  - Lu B
FAU - Kuang, Ming-Jie
AU  - Kuang MJ
FAU - Wang, Ying
AU  - Wang Y
FAU - Zhao, Yun-Long
AU  - Zhao YL
FAU - Zhao, Jie
AU  - Zhao J
FAU - Sun, Lei
AU  - Sun L
FAU - Wang, Yan
AU  - Wang Y
FAU - Ma, Jian-Xiong
AU  - Ma JX
FAU - Ma, Xin-Long
AU  - Ma XL
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - *Foot Orthoses
MH  - Humans
MH  - Osteoarthritis, Knee/*physiopathology/*therapy
EDAT- 2017/06/15 06:00
MHDA- 2017/07/07 06:00
CRDT- 2017/06/15 06:00
AID - 10.1097/MD.0000000000007168 [doi]
AID - 00005792-201706160-00039 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Jun;96(24):e7168. doi: 10.1097/MD.0000000000007168.