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Pain management of pancreatic cancer patients with high-intensity focused ultrasound therapy.

Abstract This study was performed to evaluate cancer pain control of high-Intensity focused ultrasound ablation (HIFU) and to manage the HIFU treatment pain in advanced pancreatic cancer patients with analgesics. We collected 71 locally advanced pancreatic cancer patients treated with HIFU from 2013 March to 2014 January in our hospital. The cancer pain (pre-HIFU and two weeks after HIFU) and HIFU treatment pain were evaluated respectively. The numeric rating scale (NRS) was used as the tool of pain evaluation. The related factors with pains were analyzed. The 70.42% cancer painless rate before HIFU was improved to 92.96% (P<0.05) 2 weeks after HIFU in 71 advanced pancreatic cancer patents without analgesics adjustment. The HIFU treatment pain occurred in 42 of 71 treated patients (59.15 %). The average duration was 3.93 days and pain score was 3.22. HIFU can improve cancer pain relief further in the advanced pancreatic cancer patients with third ladder analgesics, meanwhile HIFU treatment pain can be managed easy because of its short duration and low pain score.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title pakistan journal of pharmaceutical sciences
Publication Year Start




PMID- 28625958
OWN - NLM
STAT- MEDLINE
DA  - 20170619
DCOM- 20170710
LR  - 20170713
IS  - 1011-601X (Print)
IS  - 1011-601X (Linking)
VI  - 30
IP  - 1 Suppl
DP  - 2017 Jan
TI  - Pain management of pancreatic cancer patients with high-intensity focused
      ultrasound therapy.
PG  - 303-307
AB  - This study was performed to evaluate cancer pain control of high-Intensity
      focused ultrasound ablation (HIFU) and to manage the HIFU treatment pain in
      advanced pancreatic cancer patients with analgesics. We collected 71 locally
      advanced pancreatic cancer patients treated with HIFU from 2013 March to 2014
      January in our hospital. The cancer pain (pre-HIFU and two weeks after HIFU) and 
      HIFU treatment pain were evaluated respectively. The numeric rating scale (NRS)
      was used as the tool of pain evaluation. The related factors with pains were
      analyzed. The 70.42% cancer painless rate before HIFU was improved to 92.96%
      (P&lt;0.05) 2 weeks after HIFU in 71 advanced pancreatic cancer patents without
      analgesics adjustment. The HIFU treatment pain occurred in 42 of 71 treated
      patients (59.15 %). The average duration was 3.93 days and pain score was 3.22.
      HIFU can improve cancer pain relief further in the advanced pancreatic cancer
      patients with third ladder analgesics, meanwhile HIFU treatment pain can be
      managed easy because of its short duration and low pain score.
FAU - Shi, Yulan
AU  - Shi Y
AD  - Department of Surgical Oncology, the Second Affiliated Hospital, Zhejiang
      University School of Medicine, China.
FAU - Ying, Xiao
AU  - Ying X
AD  - Department of Surgical Oncology, the Second Affiliated Hospital, Zhejiang
      University School of Medicine, China.
FAU - Hu, Xiaoye
AU  - Hu X
AD  - Department of Surgical Oncology, the Second Affiliated Hospital, Zhejiang
      University School of Medicine, China.
FAU - Shen, Hong
AU  - Shen H
AD  - Department of medical Oncology, the Second Affiliated Hospital, Zhejiang
      University School of Medicine, China.
LA  - eng
PT  - Journal Article
PL  - Pakistan
TA  - Pak J Pharm Sci
JT  - Pakistan journal of pharmaceutical sciences
JID - 9426356
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cancer Pain/*therapy
MH  - Female
MH  - High-Intensity Focused Ultrasound Ablation/methods
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pain Management/*methods
MH  - Pain Measurement/methods
MH  - Pancreatic Neoplasms/*complications
MH  - Treatment Outcome
EDAT- 2017/06/20 06:00
MHDA- 2017/07/14 06:00
CRDT- 2017/06/20 06:00
PST - ppublish
SO  - Pak J Pharm Sci. 2017 Jan;30(1 Suppl):303-307.