PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Influence of protein deficient diet, vitamin Bsub2/sub supplementation and physical training on serum composition of polyunsaturated fatty acids (PUFAs) in rats.

Abstract [b]Introduction[/b]. Prolonged shortages of protein in the diet significantly alter the composition and content of polyunsaturated fatty acids (PUFA) in tissues and body fluids. One of nutritional factors which may reduce negative effects of protein malnutrition might be vitamin B[sub]2[/sub] due to its influence on lipids metabolism. [b]Objective. [/b]The aim of the study was to investigate the influence of low protein (LP) diet enriched with vitamin B[sub]2[/sub] on the content and composition of PUFA in the blood serum of rats treated with dosed physical exercise. [b]Materials and method. [/b]The experiment was carried out for 3 months on 72 growing male Wistar rats divided into 5 groups. Animals were fed ad libitum on a diet with an energy value of 350 kcal/100 g, in which 4.5% of the energy was provided by protein. In the control diet, 20% of the energy was provided by protein. Two groups were fed the diet enriched with vitamin B2. The two groups of tested animals were trained for 5 days a week. [b]Results.[/b] LP diet caused a decrease in α-linolenic acid (ALA) after 30 days, and a decrease in docosahexaenoic acid (DHA) after 60 days of experiment, compared with rats fed the control diet. After 60 and 90 days of the experiment, a significant decrease was noted in arachidonic acid (AA) in serum of trained rats, compared with sedentary rats fed the LP diet. Physical activity increased LA (mainly on day 30), EPA (on day 90) and reduced AA content (on day 90) in serum of rats fed the LP diet. B2 supplementation in the trained LP group did not change the EPA and AA dependence; however, there was a decrease in LA content in comparison to the non-supplemented trained group. [b]Conclusions. [/b] Results of this study suggest that all investigated factors (protein deficiency, physical exercise and supplementation of vitamin B2) have significant impact on PUFA composition of serum in rats.
PMID
Related Publications

Bio-availability and metabolism of n-3 fatty acid rich garden cress (Lepidium sativum) seed oil in albino rats.

Influence of folic acid, vitamin B2 and B6 supplementation on feed intake, body and organs weight, and liver fatty acids composition in rats subjected to severe protein deprivation.

Influence of vitamin B6 supplementation on polyunsaturated fatty acids concentration in serum and liver of rats fed a diet restricted in protein.

Content of polyunsaturated fatty acids (PUFAs) in serum and liver of rats fed restricted diets supplemented with vitamins B2, B6 and folic acid.

Polyunsaturated fatty acid (PUFA) changes in serum and liver of undernourished rats given dietary vitamin B6 supplementation.

Authors

Mayor MeshTerms
Keywords

Vitamin B2

protein malnutrition

pufa

training

Journal Title annals of agricultural and environmental medicine : aaem
Publication Year Start




PMID- 28664691
OWN - NLM
STAT- MEDLINE
DA  - 20170630
DCOM- 20170710
LR  - 20170713
IS  - 1898-2263 (Electronic)
IS  - 1232-1966 (Linking)
VI  - 24
IP  - 2
DP  - 2017 May 11
TI  - Influence of protein deficient diet, vitamin B[sub]2[/sub] supplementation and
      physical training on serum composition of polyunsaturated fatty acids (PUFAs) in 
      rats.
PG  - 185-189
LID - 72565 [pii]
LID - 10.5604/12321966.1228391 [doi]
AB  - [b]Introduction[/b]. Prolonged shortages of protein in the diet significantly
      alter the composition and content of polyunsaturated fatty acids (PUFA) in
      tissues and body fluids. One of nutritional factors which may reduce negative
      effects of protein malnutrition might be vitamin B[sub]2[/sub] due to its
      influence on lipids metabolism. [b]Objective. [/b]The aim of the study was to
      investigate the influence of low protein (LP) diet enriched with vitamin
      B[sub]2[/sub] on the content and composition of PUFA in the blood serum of rats
      treated with dosed physical exercise. [b]Materials and method. [/b]The experiment
      was carried out for 3 months on 72 growing male Wistar rats divided into 5
      groups. Animals were fed ad libitum on a diet with an energy value of 350
      kcal/100 g, in which 4.5% of the energy was provided by protein. In the control
      diet, 20% of the energy was provided by protein. Two groups were fed the diet
      enriched with vitamin B2. The two groups of tested animals were trained for 5
      days a week. [b]Results.[/b] LP diet caused a decrease in alpha-linolenic acid
      (ALA) after 30 days, and a decrease in docosahexaenoic acid (DHA) after 60 days
      of experiment, compared with rats fed the control diet. After 60 and 90 days of
      the experiment, a significant decrease was noted in arachidonic acid (AA) in
      serum of trained rats, compared with sedentary rats fed the LP diet. Physical
      activity increased LA (mainly on day 30), EPA (on day 90) and reduced AA content 
      (on day 90) in serum of rats fed the LP diet. B2 supplementation in the trained
      LP group did not change the EPA and AA dependence; however, there was a decrease 
      in LA content in comparison to the non-supplemented trained group.
      [b]Conclusions. [/b] Results of this study suggest that all investigated factors 
      (protein deficiency, physical exercise and supplementation of vitamin B2) have
      significant impact on PUFA composition of serum in rats.
FAU - Lewicka, Aneta
AU  - Lewicka A
AD  - Department of Hygiene and Physiology, Military Institute of Hygiene and
      Epidemiology, Warsaw, Poland.
FAU - Lewicki, Slawomir
AU  - Lewicki S
AD  - Department of Regenerative Medicine, Military Institute of Hygiene and
      Epidemiology, Warsaw, Poland.
FAU - Klos, Anna
AU  - Klos A
AD  - Department of Hygiene and Physiology, Military Institute of Hygiene and
      Epidemiology, Warsaw, Poland.
FAU - Debski, Bogdan
AU  - Debski B
AD  - Department of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw
      University of Life Sciences, Poland.
FAU - Kuryl, Tomasz
AU  - Kuryl T
AD  - Department of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw
      University of Life Sciences, Poland.
FAU - Bertrandt, Jerzy
AU  - Bertrandt J
AD  - Department of Hygiene and Physiology, Military Institute of Hygiene and
      Epidemiology, Warsaw, Poland.
LA  - eng
PT  - Journal Article
PL  - Poland
TA  - Ann Agric Environ Med
JT  - Annals of agricultural and environmental medicine : AAEM
JID - 9500166
RN  - 0 (Fatty Acids, Unsaturated)
RN  - TLM2976OFR (Riboflavin)
SB  - IM
MH  - Animals
MH  - Diet, Protein-Restricted/*adverse effects
MH  - Dietary Supplements/*analysis
MH  - Exercise
MH  - Fatty Acids, Unsaturated/*blood/chemistry
MH  - Humans
MH  - Male
MH  - Malnutrition/blood/*drug therapy/etiology/*physiopathology
MH  - Rats
MH  - Rats, Wistar
MH  - Riboflavin/*administration & dosage
OTO - NOTNLM
OT  - Vitamin B2
OT  - protein malnutrition
OT  - pufa
OT  - training
EDAT- 2017/07/01 06:00
MHDA- 2017/07/14 06:00
CRDT- 2017/07/01 06:00
AID - 72565 [pii]
AID - 10.5604/12321966.1228391 [doi]
PST - ppublish
SO  - Ann Agric Environ Med. 2017 May 11;24(2):185-189. doi: 10.5604/12321966.1228391.