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Vital Signs: Changes in Opioid Prescribing in the United States, 2006-2015.

Abstract Prescription opioid-related overdose deaths increased sharply during 1999-2010 in the United States in parallel with increased opioid prescribing. CDC assessed changes in national-level and county-level opioid prescribing during 2006-2015.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title mmwr. morbidity and mortality weekly report
Publication Year Start




PMID- 28683056
OWN - NLM
STAT- MEDLINE
DA  - 20170706
DCOM- 20170710
LR  - 20170713
IS  - 1545-861X (Electronic)
IS  - 0149-2195 (Linking)
VI  - 66
IP  - 26
DP  - 2017 Jul 07
TI  - Vital Signs: Changes in Opioid Prescribing in the United States, 2006-2015.
PG  - 697-704
LID - 10.15585/mmwr.mm6626a4 [doi]
AB  - BACKGROUND: Prescription opioid-related overdose deaths increased sharply during 
      1999-2010 in the United States in parallel with increased opioid prescribing. CDC
      assessed changes in national-level and county-level opioid prescribing during
      2006-2015. METHODS: CDC analyzed retail prescription data from QuintilesIMS to
      assess opioid prescribing in the United States from 2006 to 2015, including
      rates, amounts, dosages, and durations prescribed. CDC examined county-level
      prescribing patterns in 2010 and 2015. RESULTS: The amount of opioids prescribed 
      in the United States peaked at 782 morphine milligram equivalents (MME) per
      capita in 2010 and then decreased to 640 MME per capita in 2015. Despite
      significant decreases, the amount of opioids prescribed in 2015 remained
      approximately three times as high as in 1999 and varied substantially across the 
      country. County-level factors associated with higher amounts of prescribed
      opioids include a larger percentage of non-Hispanic whites; a higher prevalence
      of diabetes and arthritis; micropolitan status (i.e., town/city; nonmetro); and
      higher unemployment and Medicaid enrollment. CONCLUSIONS AND IMPLICATIONS FOR
      PUBLIC HEALTH PRACTICE: Despite reductions in opioid prescribing in some parts of
      the country, the amount of opioids prescribed remains high relative to 1999
      levels and varies substantially at the county-level. Given associations between
      opioid prescribing, opioid use disorder, and overdose rates, health care
      providers should carefully weigh the benefits and risks when prescribing opioids 
      outside of end-of-life care, follow evidence-based guidelines, such as CDC's
      Guideline for Prescribing Opioids for Chronic Pain, and consider nonopioid
      therapy for chronic pain treatment. State and local jurisdictions can use these
      findings combined with Prescription Drug Monitoring Program data to identify
      areas with prescribing patterns that place patients at risk for opioid use
      disorder and overdose and to target interventions with prescribers based on
      opioid prescribing guidelines.
FAU - Guy, Gery P Jr
AU  - Guy GP Jr
FAU - Zhang, Kun
AU  - Zhang K
FAU - Bohm, Michele K
AU  - Bohm MK
FAU - Losby, Jan
AU  - Losby J
FAU - Lewis, Brian
AU  - Lewis B
FAU - Young, Randall
AU  - Young R
FAU - Murphy, Louise B
AU  - Murphy LB
FAU - Dowell, Deborah
AU  - Dowell D
LA  - eng
PT  - Journal Article
DEP - 20170707
PL  - United States
TA  - MMWR Morb Mortal Wkly Rep
JT  - MMWR. Morbidity and mortality weekly report
JID - 7802429
RN  - 0 (Analgesics, Opioid)
SB  - IM
MH  - Analgesics, Opioid/poisoning/*therapeutic use
MH  - Centers for Disease Control and Prevention (U.S.)
MH  - Chronic Pain/*drug therapy
MH  - Drug Overdose/epidemiology/mortality
MH  - Drug Prescriptions/*statistics & numerical data
MH  - Humans
MH  - Opioid-Related Disorders/epidemiology
MH  - Practice Guidelines as Topic
MH  - Practice Patterns, Physicians'/standards/*statistics & numerical data
MH  - Risk
MH  - United States/epidemiology
EDAT- 2017/07/07 06:00
MHDA- 2017/07/14 06:00
CRDT- 2017/07/07 06:00
AID - 10.15585/mmwr.mm6626a4 [doi]
PST - epublish
SO  - MMWR Morb Mortal Wkly Rep. 2017 Jul 7;66(26):697-704. doi:
      10.15585/mmwr.mm6626a4.