PubTransformer

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PMID- 28687852
OWN - NLM
STAT- MEDLINE
DA  - 20170708
DCOM- 20170714
LR  - 20170714
IS  - 1552-5783 (Electronic)
IS  - 0146-0404 (Linking)
VI  - 58
IP  - 9
DP  - 2017 Jul 01
TI  - Optical Coherence Tomographic Imaging of Posterior Episclera and Tenon's Capsule.
PG  - 3389-3394
LID - 10.1167/iovs.16-21394 [doi]
AB  - Purpose: To investigate structural features of the posterior episclera and
      Tenon's capsule in patients with high myopia. Methods: This hospital-based
      observational study included highly myopic eyes (myopic refractive error > -8
      diopters or axial length >/=26.5 mm) in which the posterior sclera in its full
      thickness could be visualized on swept-source optical coherence tomography (OCT) 
      images in all 12 radial scans centered on the fovea. We assessed the posterior
      episclera and Tenon's capsule. Results: The study included 278 eyes of 175
      patients (mean age, 60.9 +/- 11.4 years; range, 32-89 years; axial length, 30.7
      +/- 1.9 mm; range, 26.5-36.6 mm). The episclera was detected outside of the
      sclera in 164 eyes (59.0%) and appeared as a relatively uniform structure with a 
      reflectivity slightly lower than scleral reflectivity. In these eyes, mean
      scleral thickness was 197 +/- 73 mum in the foveal region and 164 +/- 64 mum and 
      146 +/- 59 mum at 1000 and 2500 mum temporal to the fovea, respectively. The
      posterior episclera was visualized in the region temporal to the fovea. Mean
      episcleral thickness detected in 77 eyes was 80 +/- 27 mum and 82 +/- 30 mum at
      1000 mum and 2500 mum temporal to the fovea, respectively. Tenon's capsule was
      detected in 11 of the 278 eyes (4.0%) as structurally, loosely connected tissue
      with a meshwork-like appearance. The measured thickness in four eyes was 60 +/-
      32 mum. In 25 eyes with extremely thin sclera (<100 mum at 1000 mum temporal to
      the foveola), the mean thickness of the sclera and episclera were 87 +/- 11 mum
      and 65 +/- 15 mum, respectively. Conclusions: Swept-source OCT applied to a
      subset of highly myopic eyes with significant thinning of the retina and choroid 
      allowed visualization of the posterior sclera and episclera, and in some cases,
      also Tenon's capsule.
FAU - Ohno-Matsui, Kyoko
AU  - Ohno-Matsui K
AD  - Department of Ophthalmology and Visual Science, Tokyo Medical and Dental
      University, Tokyo, Japan.
FAU - Fang, Yuxin
AU  - Fang Y
AD  - Department of Ophthalmology and Visual Science, Tokyo Medical and Dental
      University, Tokyo, Japan.
FAU - Morohoshi, Kei
AU  - Morohoshi K
AD  - Department of Ophthalmology and Visual Science, Tokyo Medical and Dental
      University, Tokyo, Japan.
FAU - Jonas, Jost B
AU  - Jonas JB
AD  - Department of Ophthalmology, Medical Faculty Mannheim of the
      Ruprecht-Karls-University of Heidelberg, Heidelberg, Germany.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PL  - United States
TA  - Invest Ophthalmol Vis Sci
JT  - Investigative ophthalmology & visual science
JID - 7703701
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Blood Vessels/diagnostic imaging
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myopia, Degenerative/diagnostic imaging/*pathology
MH  - Sclera/diagnostic imaging/*pathology
MH  - Tenon Capsule/diagnostic imaging/*pathology
MH  - Tomography, Optical Coherence/methods
EDAT- 2017/07/09 06:00
MHDA- 2017/07/15 06:00
CRDT- 2017/07/09 06:00
AID - 2643391 [pii]
AID - 10.1167/iovs.16-21394 [doi]
PST - ppublish
SO  - Invest Ophthalmol Vis Sci. 2017 Jul 1;58(9):3389-3394. doi:
      10.1167/iovs.16-21394.