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Measles Outbreak - Minnesota April-May 2017.

Abstract On April 10, 2017, the Minnesota Department of Health (MDH) was notified about a suspected measles case. The patient was a hospitalized child aged 25 months who was evaluated for fever and rash, with onset on April 8. The child had no history of receipt of measles-mumps-rubella (MMR) vaccine and no travel history or known exposure to measles. On April 11, MDH received a report of a second hospitalized, unvaccinated child, aged 34 months, with an acute febrile rash illness with onset on April 10. The second patient's sibling, aged 19 months, who had also not received MMR vaccine, had similar symptoms, with rash onset on March 30. Real-time reverse transcription-polymerase chain reaction (rRT-PCR) testing of nasopharyngeal swab or throat specimens performed at MDH confirmed measles in the first two patients on April 11, and in the third patient on April 13; subsequent genotyping identified genotype B3 virus in all three patients, who attended the same child care center. MDH instituted outbreak investigation and response activities in collaboration with local health departments, health care facilities, child care facilities, and schools in affected settings. Because the outbreak occurred in a community with low MMR vaccination coverage, measles spread rapidly, resulting in thousands of exposures in child care centers, schools, and health care facilities. By May 31, 2017, a total of 65 confirmed measles cases had been reported to MDH (Figure 1); transmission is ongoing.
PMID
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Authors

Mayor MeshTerms

Disease Outbreaks

Keywords
Journal Title mmwr. morbidity and mortality weekly report
Publication Year Start




PMID- 28704350
OWN - NLM
STAT- MEDLINE
DA  - 20170713
DCOM- 20170714
LR  - 20170714
IS  - 1545-861X (Electronic)
IS  - 0149-2195 (Linking)
VI  - 66
IP  - 27
DP  - 2017 Jul 14
TI  - Measles Outbreak - Minnesota April-May 2017.
PG  - 713-717
LID - 10.15585/mmwr.mm6627a1 [doi]
AB  - On April 10, 2017, the Minnesota Department of Health (MDH) was notified about a 
      suspected measles case. The patient was a hospitalized child aged 25 months who
      was evaluated for fever and rash, with onset on April 8. The child had no history
      of receipt of measles-mumps-rubella (MMR) vaccine and no travel history or known 
      exposure to measles. On April 11, MDH received a report of a second hospitalized,
      unvaccinated child, aged 34 months, with an acute febrile rash illness with onset
      on April 10. The second patient's sibling, aged 19 months, who had also not
      received MMR vaccine, had similar symptoms, with rash onset on March 30.
      Real-time reverse transcription-polymerase chain reaction (rRT-PCR) testing of
      nasopharyngeal swab or throat specimens performed at MDH confirmed measles in the
      first two patients on April 11, and in the third patient on April 13; subsequent 
      genotyping identified genotype B3 virus in all three patients, who attended the
      same child care center. MDH instituted outbreak investigation and response
      activities in collaboration with local health departments, health care
      facilities, child care facilities, and schools in affected settings. Because the 
      outbreak occurred in a community with low MMR vaccination coverage, measles
      spread rapidly, resulting in thousands of exposures in child care centers,
      schools, and health care facilities. By May 31, 2017, a total of 65 confirmed
      measles cases had been reported to MDH (Figure 1); transmission is ongoing.
FAU - Hall, Victoria
AU  - Hall V
FAU - Banerjee, Emily
AU  - Banerjee E
FAU - Kenyon, Cynthia
AU  - Kenyon C
FAU - Strain, Anna
AU  - Strain A
FAU - Griffith, Jayne
AU  - Griffith J
FAU - Como-Sabetti, Kathryn
AU  - Como-Sabetti K
FAU - Heath, Jennifer
AU  - Heath J
FAU - Bahta, Lynn
AU  - Bahta L
FAU - Martin, Karen
AU  - Martin K
FAU - McMahon, Melissa
AU  - McMahon M
FAU - Johnson, Dave
AU  - Johnson D
FAU - Roddy, Margaret
AU  - Roddy M
FAU - Dunn, Denise
AU  - Dunn D
FAU - Ehresmann, Kristen
AU  - Ehresmann K
LA  - eng
PT  - Journal Article
DEP - 20170714
PL  - United States
TA  - MMWR Morb Mortal Wkly Rep
JT  - MMWR. Morbidity and mortality weekly report
JID - 7802429
RN  - 0 (Measles-Mumps-Rubella Vaccine)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Child
MH  - Child, Preschool
MH  - *Disease Outbreaks
MH  - Humans
MH  - Infant
MH  - Measles/*epidemiology/prevention & control
MH  - Measles virus/genetics/isolation & purification
MH  - Measles-Mumps-Rubella Vaccine/administration & dosage
MH  - Middle Aged
MH  - Minnesota/epidemiology
MH  - Vaccination/statistics & numerical data
MH  - Young Adult
EDAT- 2017/07/14 06:00
MHDA- 2017/07/15 06:00
CRDT- 2017/07/14 06:00
AID - 10.15585/mmwr.mm6627a1 [doi]
PST - epublish
SO  - MMWR Morb Mortal Wkly Rep. 2017 Jul 14;66(27):713-717. doi:
      10.15585/mmwr.mm6627a1.