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Case report: multiple systemic disseminated tuberculosis mimicking lymphoma on 18F-FDG PET/CT.

Abstract F-fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) has an important role in the diagnosis of various malignancies. However, F-18 FDG can also exhibit intense accumulation in tissues in inflammatory conditions such as active tuberculosis (TB) and sarcoidosis.
PMID
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Authors

Mayor MeshTerms

Fluorodeoxyglucose F18

Positron Emission Tomography Computed Tomography

Radiopharmaceuticals

Keywords
Journal Title medicine
Publication Year Start




PMID- 28723740
OWN - NLM
STAT- MEDLINE
DA  - 20170720
DCOM- 20170728
LR  - 20170728
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 29
DP  - 2017 Jul
TI  - Case report: multiple systemic disseminated tuberculosis mimicking lymphoma on
      18F-FDG PET/CT.
PG  - e7248
LID - 10.1097/MD.0000000000007248 [doi]
AB  - RATIONALE: F-fluorodeoxyglucose positron emission tomography/computed tomography 
      (F-18 FDG PET/CT) has an important role in the diagnosis of various malignancies.
      However, F-18 FDG can also exhibit intense accumulation in tissues in
      inflammatory conditions such as active tuberculosis (TB) and sarcoidosis. PATIENT
      CONCERNS: We report a case of a 52-year-old female with irritable cough. CT
      showed a lung mass with multiple bilateral lung nodules, and sarcoidosis was
      suspected. F-18 FDG PET/CT was undertaken for the diagnosis and showed intense
      uptake of FDG in the mass in the lower lobe of the right lung, multiple lymph
      nodes, liver, and spleen. The maximum standardized uptake value of F-18 FDG was
      43.58. This pattern of involvement most likely represents lymphomatous
      involvement. DIAGNOSES: Histopathology suggested tubercular involvement.
      INTERVENTION AND OUTCOMES: The patient received anti-TB treatment and recovered. 
      LESSONS: Abovementioned extent and distribution of F-18 FDG in tubercular lesion 
      is relatively rare, thus, one must be observant and aware with regards to TB
      being a strong mimic of lymphoma in endemic regions.
FAU - Hou, Shasha
AU  - Hou S
AD  - aDepartment of Nuclear Medicine, Tianjin Medical University General Hospital,
      Heping District bDepartment of Nuclear Medicine, Tianjin First Central Hospital, 
      TianJin China.
FAU - Shen, Jie
AU  - Shen J
FAU - Tan, Jian
AU  - Tan J
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Antitubercular Agents)
RN  - 0 (Radiopharmaceuticals)
RN  - 0Z5B2CJX4D (Fluorodeoxyglucose F18)
SB  - AIM
SB  - IM
MH  - Antitubercular Agents/therapeutic use
MH  - Diagnosis, Differential
MH  - Female
MH  - *Fluorodeoxyglucose F18
MH  - Humans
MH  - Lymphoma/*diagnostic imaging
MH  - Middle Aged
MH  - *Positron Emission Tomography Computed Tomography
MH  - *Radiopharmaceuticals
MH  - Tuberculosis/*diagnostic imaging/drug therapy/pathology
MH  - Whole Body Imaging
EDAT- 2017/07/21 06:00
MHDA- 2017/07/29 06:00
CRDT- 2017/07/21 06:00
AID - 10.1097/MD.0000000000007248 [doi]
AID - 00005792-201707210-00005 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Jul;96(29):e7248. doi: 10.1097/MD.0000000000007248.