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Malignant melanoma misdiagnosed as diabetic foot ulcer: A case report.

Abstract Acral lentiginous melanoma (AML) does not exhibit the classic signs of malignant melanoma. ALM is frequently misdiagnosed because of its unusual sites and atypical clinical morphologies, which lead to poor prognosis.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 28723771
OWN - NLM
STAT- MEDLINE
DA  - 20170720
DCOM- 20170728
LR  - 20170728
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 29
DP  - 2017 Jul
TI  - Malignant melanoma misdiagnosed as diabetic foot ulcer: A case report.
PG  - e7541
LID - 10.1097/MD.0000000000007541 [doi]
AB  - RATIONALE: Acral lentiginous melanoma (AML) does not exhibit the classic signs of
      malignant melanoma. ALM is frequently misdiagnosed because of its unusual sites
      and atypical clinical morphologies, which lead to poor prognosis. PATIENT
      CONCERNS: A female patient aged 78 years was presented to our center with two
      ulcers on her right foot. Diabetic foot ulcer was considered as the primary
      diagnosis. The ulcers failed to improve after 2 weeks' therapy. DIAGNOSES: An
      incisional biopsy of the lesion revealed malignant melanoma. INTERVENTIONS: The
      patient received wide excision, skin grafting as well as biotherapy. OUTCOMES:
      The lesion was healed and no other metastasis has been founded until now.
      LESSONS: Clinicians must maintain a high level of suspicion in distinguishing
      malignant melanoma from other more benign skin lesions of the foot. The need for 
      early biopsy of ulcer, even when clinical suspicion is low, can not be
      overemphasized. Only in this way can we reduce misdiagnosis rate and improve
      survival rate in patients with foot ulcer.
FAU - Gao, Wei
AU  - Gao W
AD  - aDepartment of Endocrinology and Metabolism bHealth Management Center cDiabetic
      Foot Care Center, West China Hospital, Sichuan University, Chengdu, Sichuan,
      China.
FAU - Chen, Dawei
AU  - Chen D
FAU - Ran, Xingwu
AU  - Ran X
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - Melanoma, Cutaneous Malignant
SB  - AIM
SB  - IM
MH  - Aged
MH  - Diabetes Mellitus, Type 2/complications
MH  - Diabetic Foot/*diagnosis/drug therapy/pathology
MH  - Diagnostic Errors
MH  - Female
MH  - Foot/pathology/surgery
MH  - Humans
MH  - Melanoma/*diagnosis/pathology/therapy
MH  - Skin Neoplasms/*diagnosis/pathology/therapy
EDAT- 2017/07/21 06:00
MHDA- 2017/07/29 06:00
CRDT- 2017/07/21 06:00
AID - 10.1097/MD.0000000000007541 [doi]
AID - 00005792-201707210-00036 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Jul;96(29):e7541. doi: 10.1097/MD.0000000000007541.