PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Prognostic value of neutrophil-to-lymphocyte ratio for nasopharyngeal carcinoma: A meta-analysis.

Abstract The prognostic value of the neutrophil-to-lymphocyte ratio (NLR) for nasopharyngeal carcinoma (NPC) remains controversial. This study was designed to provide a more accurate assessment of the prognostic value, based on a meta-analysis.
PMID
Related Publications

Prognostic significance of neutrophil-to-lymphocyte ratio in non-small cell lung cancer: a meta-analysis.

Prognostic significance of neutrophil-to-lymphocyte ratio in diffuse large B-cell lymphoma: A meta-analysis.

Prognostic role of neutrophil-lymphocyte ratio in nasopharyngeal carcinoma: A meta-analysis.

Prognostic role of neutrophil to lymphocyte ratio in lung cancers: a meta-analysis including 7,054 patients.

Pretreatment hematologic markers as prognostic factors in patients with nasopharyngeal carcinoma: A systematic review and meta-analysis.

Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 28723793
OWN - NLM
STAT- In-Process
DA  - 20170720
LR  - 20170720
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 29
DP  - 2017 Jul
TI  - Prognostic value of neutrophil-to-lymphocyte ratio for nasopharyngeal carcinoma: 
      A meta-analysis.
PG  - e7577
LID - 10.1097/MD.0000000000007577 [doi]
AB  - BACKGROUND: The prognostic value of the neutrophil-to-lymphocyte ratio (NLR) for 
      nasopharyngeal carcinoma (NPC) remains controversial. This study was designed to 
      provide a more accurate assessment of the prognostic value, based on a
      meta-analysis. METHODS: A comprehensive search for relevant studies published
      before June 2016 was performed using the PubMed, Cochrane Library, and Web of
      Science databases. The correlations of NLR with overall survival (OS) and
      progression-free survival (PFS) were evaluated for NPC. Hazard ratios (HRs) and
      associated 95% confidence intervals (CIs) were calculated to estimate the
      effects. RESULTS: Six studies with a total of 4359 NPC patients were included in 
      this meta-analysis. The pooled results showed that, among patients with NPC,
      elevated pretreatment NLR was associated with poorer OS (HR = 1.74, 95% CI =
      1.45-2.10) and PFS (HR = 1.48, 95% CI = 1.30-1.69). Subgroup analyses indicated
      that the use of different cut-off values for NLR (<3 or >/=3) did not affect the 
      consistent prognostic value of NLR for OS or PFS. No significant heterogeneity or
      publication bias was observed among the included studies for OS or PFS (P > .05).
      CONCLUSIONS: This meta-analysis indicates that elevated pretreatment NLR might be
      a valuable predicative biomarker of poor prognosis for patients with NPC.
FAU - Yin, Jun
AU  - Yin J
AD  - Department of Radiation Oncology, Sichuan Cancer Hospital & Institute, Sichuan
      Cancer Center, School of Medicine, University of Electronic Science and
      Technology of China, Chengdu, Sichuan, China.
FAU - Qin, Yuan
AU  - Qin Y
FAU - Luo, Yu-Kun
AU  - Luo YK
FAU - Feng, Mei
AU  - Feng M
FAU - Lang, Jin-Yi
AU  - Lang JY
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
EDAT- 2017/07/21 06:00
MHDA- 2017/07/21 06:00
CRDT- 2017/07/21 06:00
AID - 10.1097/MD.0000000000007577 [doi]
AID - 00005792-201707210-00058 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Jul;96(29):e7577. doi: 10.1097/MD.0000000000007577.