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Leukoencephalopathy with calcifications and cysts: A case report.

Abstract Leukoencephalopathy with calcifications and cysts (LCC) is an uncommon entity characterized by edematous leukoencephalopathy, cerebral calcifications, and parenchymal cysts. Due to its rarity, the clinical, radiological, and histopathological features have yet to be well elucidated.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 28723803
OWN - NLM
STAT- MEDLINE
DA  - 20170720
DCOM- 20170808
LR  - 20170808
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 29
DP  - 2017 Jul
TI  - Leukoencephalopathy with calcifications and cysts: A case report.
PG  - e7597
LID - 10.1097/MD.0000000000007597 [doi]
AB  - RATIONALE: Leukoencephalopathy with calcifications and cysts (LCC) is an uncommon
      entity characterized by edematous leukoencephalopathy, cerebral calcifications,
      and parenchymal cysts. Due to its rarity, the clinical, radiological, and
      histopathological features have yet to be well elucidated. PATIENT CONCERNS: The 
      first case is a 35-year-old female who was asymptomatic. A giant intracranial
      cyst was incidentally detected radiologically, and it was slowly growing in the
      recent 10 years. The second case is a 20-year-old female who presented with a
      1-month history of headache. Brain computed tomography showed multiple asymmetric
      calcifications in the bilateral basal ganglia and white matter. Magnetic
      resonance imaging revealed a cyst in the right parietal lobe. DIAGNOSES: They
      were diagnosed with LCC. INTERVENTIONS AND OUTCOMES: The first patient underwent 
      surgical resection of the intracranial cyst, and the second patient received a
      stereotactic biopsy. The patients performed well postoperatively. LESSONS: LCC
      can be found at any age. A young age seems to be associated with severer
      symptoms. The clinical manifestations can be variable and aggressive. The
      potential pathogenic basis still needs further research.
FAU - Ma, Yubao
AU  - Ma Y
AD  - aDepartment of Neurology, Chinese PLA General Hospital, Beijing bDepartment of
      Neurology, Tianjin Medical University General Hospital, Tianjin, People's
      Republic of China.
FAU - Zhang, Xingwen
AU  - Zhang X
FAU - Cheng, Chen
AU  - Cheng C
FAU - Xu, Quangang
AU  - Xu Q
FAU - Di, Hai
AU  - Di H
FAU - Zhao, Jiao
AU  - Zhao J
FAU - Huang, Dehui
AU  - Huang D
FAU - Yu, Shengyuan
AU  - Yu S
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - AIM
SB  - IM
MH  - Adult
MH  - Brain/diagnostic imaging/pathology/surgery
MH  - Calcinosis/*complications/*diagnostic imaging/pathology/surgery
MH  - Cysts/*complications/*diagnostic imaging/pathology/surgery
MH  - Diagnosis, Differential
MH  - Female
MH  - Humans
MH  - Leukoencephalopathies/*complications/*diagnostic imaging/pathology/surgery
MH  - Young Adult
PMC - PMC5521943
EDAT- 2017/07/21 06:00
MHDA- 2017/08/09 06:00
CRDT- 2017/07/21 06:00
AID - 10.1097/MD.0000000000007597 [doi]
AID - 00005792-201707210-00068 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Jul;96(29):e7597. doi: 10.1097/MD.0000000000007597.