PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.




PMID- 28739768
OWN - NLM
STAT- MEDLINE
DA  - 20170725
DCOM- 20170803
LR  - 20170803
IS  - 1791-7530 (Electronic)
IS  - 0250-7005 (Linking)
VI  - 37
IP  - 8
DP  - 2017 Aug
TI  - Preoperative High Neutrophil-to-Lymphocyte Ratio Is Associated with High-grade
      Bladder Cancer.
PG  - 4659-4663
AB  - AIM: To evaluate the correlation between the neutrophil-to-lymphocyte ratio (NLR)
      and histopathological characteristics of bladder cancer. MATERIALS AND METHODS: A
      retrospective analysis was performed on a cohort of patients (n=302) who were
      diagnosed with bladder cancer and underwent transurethral resection of bladder
      tumor or cystectomy between 2009 and 2016. The pathological outcomes were
      compared between patients with low NLR and those with high NLR with a cut-off
      value of 2.5, and a logistic regression analysis was performed to find potential 
      predictors of pathological tumor outcomes. RESULTS: Patients with high-grade
      disease had significantly higher NLRs compared to those with low-grade disease
      (median NLR=4.42 vs. 3.42, p<0.001). Univariate analysis suggested that age,
      neutrophil count and NLR, as a continuous or binary variable, were significantly 
      associated with high-grade disease. Multivariate analysis suggested that age and 
      NLR, as a continuous variable, were predictors of pathologically high-grade
      disease. CONCLUSION: Preoperative NLR was found to be associated with
      pathological tumor grading, but was not associated with pathological tumor
      staging in patients with bladder cancer.
CI  - Copyright(c) 2017, International Institute of Anticancer Research (Dr. George J. 
      Delinasios), All rights reserved.
FAU - Tang, Xingxing
AU  - Tang X
AD  - Key Laboratory of Carcinogenesis and Translational Research (Ministry of
      Education), Department of Urology, Peking University Cancer Hospital & Institute,
      Beijing, P.R. China.
FAU - Wang, Shuo
AU  - Wang S
AD  - Key Laboratory of Carcinogenesis and Translational Research (Ministry of
      Education), Department of Urology, Peking University Cancer Hospital & Institute,
      Beijing, P.R. China.
FAU - An, Chao
AU  - An C
AD  - Key Laboratory of Carcinogenesis and Translational Research (Ministry of
      Education), Department of Urology, Peking University Cancer Hospital & Institute,
      Beijing, P.R. China.
FAU - DU, Peng
AU  - DU P
AD  - Key Laboratory of Carcinogenesis and Translational Research (Ministry of
      Education), Department of Urology, Peking University Cancer Hospital & Institute,
      Beijing, P.R. China [email protected]
FAU - Yang, Yong
AU  - Yang Y
AD  - Key Laboratory of Carcinogenesis and Translational Research (Ministry of
      Education), Department of Urology, Peking University Cancer Hospital & Institute,
      Beijing, P.R. China.
LA  - eng
PT  - Journal Article
PL  - Greece
TA  - Anticancer Res
JT  - Anticancer research
JID - 8102988
SB  - IM
MH  - Aged
MH  - Female
MH  - Humans
MH  - *Leukocyte Count
MH  - *Lymphocytes
MH  - Male
MH  - Middle Aged
MH  - Neoplasm Grading
MH  - Neoplasm Metastasis
MH  - Neoplasm Staging
MH  - *Neutrophils
MH  - Preoperative Period
MH  - Retrospective Studies
MH  - Urinary Bladder Neoplasms/*blood/*pathology/surgery
OTO - NOTNLM
OT  - Neutrophil to lymphocyte ratio
OT  - bladder cancer
OT  - pathological outcome
EDAT- 2017/07/26 06:00
MHDA- 2017/08/05 06:00
CRDT- 2017/07/26 06:00
PHST- 2017/05/02 [received]
PHST- 2017/06/07 [revised]
PHST- 2017/06/13 [accepted]
AID - 37/8/4659 [pii]
PST - ppublish
SO  - Anticancer Res. 2017 Aug;37(8):4659-4663.