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A rare case of iron-pill induced gastritis in a female teenager: A case report and a review of the literature.

Abstract The treatment of iron-deficiency anemia with oral iron supplements can present side-effects on the GI tract mucosa including necrosis, ulceration, or ischemia. The particular endoscopic findings and the histopathological exam will establish the diagnosis of erosive gastritis with iron deposits in the gastric mucosa.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 28746201
OWN - NLM
STAT- MEDLINE
DA  - 20170726
DCOM- 20170807
LR  - 20170807
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 30
DP  - 2017 Jul
TI  - A rare case of iron-pill induced gastritis in a female teenager: A case report
      and a review of the literature.
PG  - e7550
LID - 10.1097/MD.0000000000007550 [doi]
AB  - RATIONALE: The treatment of iron-deficiency anemia with oral iron supplements can
      present side-effects on the GI tract mucosa including necrosis, ulceration, or
      ischemia. The particular endoscopic findings and the histopathological exam will 
      establish the diagnosis of erosive gastritis with iron deposits in the gastric
      mucosa. PATIENT CONCERNS: We present the case of a 14-year-old female admitted in
      our clinic for upper digestive hemorrhage, nausea, melena, and abdominal pain.
      Her personal history revealed iron deficiency anemia receiving oral iron
      supplements for approximately 2 weeks. DIAGNOSIS: The laboratory tests at the
      moment of admission pointed out anemia, increased level of serum iron, increased 
      liver transaminases, a decreased level of ferritin, but with normal levels of
      both total iron-binding capacity and transferrin. INTERVENTIONS: The
      eso-gastro-duodenoscopy revealed multiple brown deposits on the surface of the
      gastric mucosa and multiple hemorrhagic lesions, under the aspect of erosions all
      over the gastric mucosa, but more severe in the antral part, and the
      histopathological exam confirmed the presence of iron deposits at this level.
      CONCLUSION: Iron-pill induced gastritis is a rare, under-diagnosed entity that
      can be present even at pediatric ages with potential severe clinical impact.
FAU - Melit, Lorena Elena
AU  - Melit LE
AD  - aDepartment of Pediatrics I, University of Medicine and Pharmacy bDepartment of
      Pathology, County Hospital, Tirgu Mures, Romania.
FAU - Marginean, Cristina Oana
AU  - Marginean CO
FAU - Mocanu, Simona
AU  - Mocanu S
FAU - Marginean, Maria Oana
AU  - Marginean MO
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - E1UOL152H7 (Iron)
SB  - AIM
SB  - IM
MH  - Adolescent
MH  - Anemia, Iron-Deficiency/blood/*diet therapy
MH  - Dietary Supplements/*adverse effects
MH  - Female
MH  - Gastritis/blood/diagnostic imaging/*etiology/therapy
MH  - Humans
MH  - Iron/*administration & dosage/*adverse effects
EDAT- 2017/07/27 06:00
MHDA- 2017/08/08 06:00
CRDT- 2017/07/27 06:00
AID - 10.1097/MD.0000000000007550 [doi]
AID - 00005792-201707280-00032 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Jul;96(30):e7550. doi: 10.1097/MD.0000000000007550.