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Chondroblastic osteosarcoma of the distal tibia: a rare case report.

Abstract Chondroblastic osteosarcoma, representing about 25% of osteosarcoma, is a fatal primary malignancy of the skeleton if not diagnosed and treated appropriately. It most commonly occurs in the long bones of the extremities near the metaphyseal growth plates. In this report, we describe the occurrence of chondroblastic osteosarcoma involving the left distal tibia in a 14-year-old male. The diagnosis was confirmed by the histological examination of a surgical biopsy. The patient was treated by both surgery and neoadjuvant chemotherapy. No recurrence was noted at 3 years of follow-up. To our knowledge, only two cases describing chondroblastic osteosarcoma of the distal tibia had been reported through English medical literature. Therefore, the aim of our article is to make the clinician aware of this rare clinical presentation and also to provide a comprehensive review of the literature related to this uncommon malignant tumour.
PMID
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Authors

Mayor MeshTerms
Keywords

Osteosarcoma

chondroblastic

tibia

Journal Title the pan african medical journal
Publication Year Start




PMID- 28748013
OWN - NLM
STAT- MEDLINE
DA  - 20170727
DCOM- 20170804
LR  - 20170804
IS  - 1937-8688 (Electronic)
VI  - 27
DP  - 2017
TI  - Chondroblastic osteosarcoma of the distal tibia: a rare case report.
PG  - 11
LID - 10.11604/pamj.2017.27.11.12418 [doi]
AB  - Chondroblastic osteosarcoma, representing about 25% of osteosarcoma, is a fatal
      primary malignancy of the skeleton if not diagnosed and treated appropriately. It
      most commonly occurs in the long bones of the extremities near the metaphyseal
      growth plates. In this report, we describe the occurrence of chondroblastic
      osteosarcoma involving the left distal tibia in a 14-year-old male. The diagnosis
      was confirmed by the histological examination of a surgical biopsy. The patient
      was treated by both surgery and neoadjuvant chemotherapy. No recurrence was noted
      at 3 years of follow-up. To our knowledge, only two cases describing
      chondroblastic osteosarcoma of the distal tibia had been reported through English
      medical literature. Therefore, the aim of our article is to make the clinician
      aware of this rare clinical presentation and also to provide a comprehensive
      review of the literature related to this uncommon malignant tumour.
FAU - Fredj, Aymen Ben
AU  - Fredj AB
AD  - Department of Orthopaedic Surgery, University Hospital, Monastir, Tunisia.
FAU - Hassini, Lassaad
AU  - Hassini L
AD  - Department of Orthopaedic Surgery, University Hospital, Monastir, Tunisia.
FAU - Fekih, Aymen
AU  - Fekih A
AD  - Department of Orthopaedic Surgery, University Hospital, Monastir, Tunisia.
FAU - Allagui, Mohamed
AU  - Allagui M
AD  - Department of Orthopaedic Surgery, University Hospital, Monastir, Tunisia.
FAU - Aloui, Issam
AU  - Aloui I
AD  - Department of Orthopaedic Surgery, University Hospital, Monastir, Tunisia.
FAU - Abid, Abderrazek
AU  - Abid A
AD  - Department of Orthopaedic Surgery, University Hospital, Monastir, Tunisia.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20170505
PL  - Uganda
TA  - Pan Afr Med J
JT  - The Pan African medical journal
JID - 101517926
SB  - IM
MH  - Adolescent
MH  - Biopsy
MH  - Bone Neoplasms/diagnosis/*pathology/therapy
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Neoadjuvant Therapy/methods
MH  - Osteosarcoma/diagnosis/*pathology/therapy
MH  - Tibia/*pathology
PMC - PMC5511719
OTO - NOTNLM
OT  - Osteosarcoma
OT  - chondroblastic
OT  - tibia
EDAT- 2017/07/28 06:00
MHDA- 2017/08/05 06:00
CRDT- 2017/07/28 06:00
PHST- 2017/04/03 [received]
PHST- 2017/04/28 [accepted]
AID - 10.11604/pamj.2017.27.11.12418 [doi]
AID - PAMJ-27-11 [pii]
PST - epublish
SO  - Pan Afr Med J. 2017 May 5;27:11. doi: 10.11604/pamj.2017.27.11.12418. eCollection
      2017.