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Update: Interim Guidance for Health Care Providers Caring for Pregnant Women with Possible Zika Virus Exposure - United States (Including U.S. Territories), July 2017.

Abstract CDC has updated the interim guidance for U.S. health care providers caring for pregnant women with possible Zika virus exposure in response to 1) declining prevalence of Zika virus disease in the World Health Organization's Region of the Americas (Americas) and 2) emerging evidence indicating prolonged detection of Zika virus immunoglobulin M (IgM) antibodies. Zika virus cases were first reported in the Americas during 2015-2016; however, the incidence of Zika virus disease has since declined. As the prevalence of Zika virus disease declines, the likelihood of false-positive test results increases. In addition, emerging epidemiologic and laboratory data indicate that, as is the case with other flaviviruses, Zika virus IgM antibodies can persist beyond 12 weeks after infection. Therefore, IgM test results cannot always reliably distinguish between an infection that occurred during the current pregnancy and one that occurred before the current pregnancy, particularly for women with possible Zika virus exposure before the current pregnancy. These limitations should be considered when counseling pregnant women about the risks and benefits of testing for Zika virus infection during pregnancy. This updated guidance emphasizes a shared decision-making model for testing and screening pregnant women, one in which patients and providers work together to make decisions about testing and care plans based on patient preferences and values, clinical judgment, and a balanced assessment of risks and expected outcomes.
PMID
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Update: Interim Guidance for Health Care Providers Caring for Pregnant Women with Possible Zika Virus Exposure - United States, July 2016.

Authors

Mayor MeshTerms

Health Personnel

Practice Guidelines as Topic

Keywords
Journal Title mmwr. morbidity and mortality weekly report
Publication Year Start




PMID- 28749921
OWN - NLM
STAT- MEDLINE
DA  - 20170727
DCOM- 20170731
LR  - 20170731
IS  - 1545-861X (Electronic)
IS  - 0149-2195 (Linking)
VI  - 66
IP  - 29
DP  - 2017 Jul 28
TI  - Update: Interim Guidance for Health Care Providers Caring for Pregnant Women with
      Possible Zika Virus Exposure - United States (Including U.S. Territories), July
      2017.
PG  - 781-793
LID - 10.15585/mmwr.mm6629e1 [doi]
AB  - CDC has updated the interim guidance for U.S. health care providers caring for
      pregnant women with possible Zika virus exposure in response to 1) declining
      prevalence of Zika virus disease in the World Health Organization's Region of the
      Americas (Americas) and 2) emerging evidence indicating prolonged detection of
      Zika virus immunoglobulin M (IgM) antibodies. Zika virus cases were first
      reported in the Americas during 2015-2016; however, the incidence of Zika virus
      disease has since declined. As the prevalence of Zika virus disease declines, the
      likelihood of false-positive test results increases. In addition, emerging
      epidemiologic and laboratory data indicate that, as is the case with other
      flaviviruses, Zika virus IgM antibodies can persist beyond 12 weeks after
      infection. Therefore, IgM test results cannot always reliably distinguish between
      an infection that occurred during the current pregnancy and one that occurred
      before the current pregnancy, particularly for women with possible Zika virus
      exposure before the current pregnancy. These limitations should be considered
      when counseling pregnant women about the risks and benefits of testing for Zika
      virus infection during pregnancy. This updated guidance emphasizes a shared
      decision-making model for testing and screening pregnant women, one in which
      patients and providers work together to make decisions about testing and care
      plans based on patient preferences and values, clinical judgment, and a balanced 
      assessment of risks and expected outcomes.
FAU - Oduyebo, Titilope
AU  - Oduyebo T
AD  - Zika Virus Response Team, CDC.
FAU - Polen, Kara D
AU  - Polen KD
AD  - Zika Virus Response Team, CDC.
FAU - Walke, Henry T
AU  - Walke HT
AD  - Zika Virus Response Team, CDC.
FAU - Reagan-Steiner, Sarah
AU  - Reagan-Steiner S
AD  - Zika Virus Response Team, CDC.
FAU - Lathrop, Eva
AU  - Lathrop E
AD  - Zika Virus Response Team, CDC.
FAU - Rabe, Ingrid B
AU  - Rabe IB
AD  - Zika Virus Response Team, CDC.
FAU - Kuhnert-Tallman, Wendi L
AU  - Kuhnert-Tallman WL
AD  - Zika Virus Response Team, CDC.
FAU - Martin, Stacey W
AU  - Martin SW
AD  - Zika Virus Response Team, CDC.
FAU - Walker, Allison T
AU  - Walker AT
AD  - Zika Virus Response Team, CDC.
FAU - Gregory, Christopher J
AU  - Gregory CJ
AD  - Zika Virus Response Team, CDC.
FAU - Ades, Edwin W
AU  - Ades EW
AD  - Zika Virus Response Team, CDC.
FAU - Carroll, Darin S
AU  - Carroll DS
AD  - Zika Virus Response Team, CDC.
FAU - Rivera, Maria
AU  - Rivera M
AD  - Zika Virus Response Team, CDC.
FAU - Perez-Padilla, Janice
AU  - Perez-Padilla J
AD  - Zika Virus Response Team, CDC.
FAU - Gould, Carolyn
AU  - Gould C
AD  - Zika Virus Response Team, CDC.
FAU - Nemhauser, Jeffrey B
AU  - Nemhauser JB
AD  - Zika Virus Response Team, CDC.
FAU - Ben Beard, C
AU  - Ben Beard C
AD  - Zika Virus Response Team, CDC.
FAU - Harcourt, Jennifer L
AU  - Harcourt JL
AD  - Zika Virus Response Team, CDC.
FAU - Viens, Laura
AU  - Viens L
AD  - Zika Virus Response Team, CDC.
FAU - Johansson, Michael
AU  - Johansson M
AD  - Zika Virus Response Team, CDC.
FAU - Ellington, Sascha R
AU  - Ellington SR
AD  - Zika Virus Response Team, CDC.
FAU - Petersen, Emily
AU  - Petersen E
AD  - Zika Virus Response Team, CDC.
FAU - Smith, Laura A
AU  - Smith LA
AD  - Zika Virus Response Team, CDC.
FAU - Reichard, Jessica
AU  - Reichard J
AD  - Zika Virus Response Team, CDC.
FAU - Munoz-Jordan, Jorge
AU  - Munoz-Jordan J
AD  - Zika Virus Response Team, CDC.
FAU - Beach, Michael J
AU  - Beach MJ
AD  - Zika Virus Response Team, CDC.
FAU - Rose, Dale A
AU  - Rose DA
AD  - Zika Virus Response Team, CDC.
FAU - Barzilay, Ezra
AU  - Barzilay E
AD  - Zika Virus Response Team, CDC.
FAU - Noonan-Smith, Michelle
AU  - Noonan-Smith M
AD  - Zika Virus Response Team, CDC.
FAU - Jamieson, Denise J
AU  - Jamieson DJ
AD  - Zika Virus Response Team, CDC.
FAU - Zaki, Sherif R
AU  - Zaki SR
AD  - Zika Virus Response Team, CDC.
FAU - Petersen, Lyle R
AU  - Petersen LR
AD  - Zika Virus Response Team, CDC.
FAU - Honein, Margaret A
AU  - Honein MA
AD  - Zika Virus Response Team, CDC.
FAU - Meaney-Delman, Dana
AU  - Meaney-Delman D
AD  - Zika Virus Response Team, CDC.
LA  - eng
PT  - Journal Article
DEP - 20170728
PL  - United States
TA  - MMWR Morb Mortal Wkly Rep
JT  - MMWR. Morbidity and mortality weekly report
JID - 7802429
SB  - IM
MH  - Centers for Disease Control and Prevention (U.S.)
MH  - Female
MH  - *Health Personnel
MH  - Humans
MH  - *Practice Guidelines as Topic
MH  - Pregnancy
MH  - Pregnancy Complications, Infectious/*prevention & control
MH  - United States
MH  - Zika Virus Infection/*prevention & control
EDAT- 2017/07/28 06:00
MHDA- 2017/08/02 06:00
CRDT- 2017/07/28 06:00
AID - 10.15585/mmwr.mm6629e1 [doi]
PST - epublish
SO  - MMWR Morb Mortal Wkly Rep. 2017 Jul 28;66(29):781-793. doi:
      10.15585/mmwr.mm6629e1.