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Drugs and the Kidneys: Clinical Pharmacology Perspectives.

Abstract The focus of this edition of Clinical Pharmacolgoy & Therapeutics (CPT) is on drugs and renal function and will not include a detailed discussion of kidney disease and its treatment. It is well recognized that drugs affect the kidneys in different ways, while kidney disease impacts drug metabolism and response. It is impossible to underestimate the value of the kidneys to man in health and disease, from regulation of fluid and electrolyte balance to participating in drug metabolism and transport. Additionally, the kidneys serve as targets for drugs used to treat cardiovascular (CV) diseases including hypertension and heart failure, metabolic diseases such as diabetes mellitus and obesity, chronic kidney disease (CKD), as well as playing a role in the regulation of several hormones. Kidney damage may be distinguished from changes in kidney function using biomarkers, as discussed in some detail in this issue.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title clinical pharmacology and therapeutics
Publication Year Start




PMID- 28782823
OWN - NLM
STAT- In-Process
DA  - 20170807
LR  - 20170807
IS  - 1532-6535 (Electronic)
IS  - 0009-9236 (Linking)
VI  - 102
IP  - 3
DP  - 2017 Sep
TI  - Drugs and the Kidneys: Clinical Pharmacology Perspectives.
PG  - 368-372
LID - 10.1002/cpt.775 [doi]
AB  - The focus of this edition of Clinical Pharmacolgoy & Therapeutics (CPT) is on
      drugs and renal function and will not include a detailed discussion of kidney
      disease and its treatment. It is well recognized that drugs affect the kidneys in
      different ways, while kidney disease impacts drug metabolism and response. It is 
      impossible to underestimate the value of the kidneys to man in health and
      disease, from regulation of fluid and electrolyte balance to participating in
      drug metabolism and transport. Additionally, the kidneys serve as targets for
      drugs used to treat cardiovascular (CV) diseases including hypertension and heart
      failure, metabolic diseases such as diabetes mellitus and obesity, chronic kidney
      disease (CKD), as well as playing a role in the regulation of several hormones.
      Kidney damage may be distinguished from changes in kidney function using
      biomarkers, as discussed in some detail in this issue.
CI  - (c) 2017 ASCPT.
FAU - Vincent, John
AU  - Vincent J
AD  - Pfizer Inc., New York, New York, USA.
LA  - eng
PT  - Editorial
PL  - United States
TA  - Clin Pharmacol Ther
JT  - Clinical pharmacology and therapeutics
JID - 0372741
EDAT- 2017/08/08 06:00
MHDA- 2017/08/08 06:00
CRDT- 2017/08/08 06:00
PHST- 2017/06/19 [received]
PHST- 2017/06/19 [accepted]
AID - 10.1002/cpt.775 [doi]
PST - ppublish
SO  - Clin Pharmacol Ther. 2017 Sep;102(3):368-372. doi: 10.1002/cpt.775.