PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Short and long-term prognostic value of hyponatremia in heart failure with preserved ejection fraction versus reduced ejection fraction: An analysis of the Korean Acute Heart Failure registry.

Abstract Hyponatremia is a well-known risk factor for worse outcomes in heart failure (HF) patients. The impact of hyponatremia according to the ejection fraction (EF) is unclear. We evaluated the prognostic value of hyponatremia according to HF type.
PMID
Related Publications

Relation of serum sodium level to long-term outcome after a first hospitalization for heart failure with preserved ejection fraction.

Atrial Fibrillation in Heart Failure With Preserved, Mid-Range, and Reduced Ejection Fraction.

Comparison of 5-Year Outcomes After Coronary Artery Bypass Grafting in Heart Failure Patients With Versus Without Preserved Left Ventricular Ejection Fraction (from the CREDO-Kyoto CABG Registry Cohort-2).

In-hospital and 1-year outcomes of acute heart failure patients according to presentation (de novo vs. worsening) and ejection fraction. Results from IN-HF Outcome Registry.

Prognostic significance of hyponatremia among ambulatory patients with heart failure and preserved and reduced ejection fractions.

Authors

Mayor MeshTerms
Keywords

Heart failure with preserved ejection fraction

Heart failure with reduced ejection fraction

Hyponatremia

Prognosis

Journal Title international journal of cardiology
Publication Year Start




PMID- 28821416
OWN - NLM
STAT- Publisher
DA  - 20170819
LR  - 20170819
IS  - 1874-1754 (Electronic)
IS  - 0167-5273 (Linking)
DP  - 2017 Aug 05
TI  - Short and long-term prognostic value of hyponatremia in heart failure with
      preserved ejection fraction versus reduced ejection fraction: An analysis of the 
      Korean Acute Heart Failure registry.
LID - S0167-5273(17)33597-0 [pii]
LID - 10.1016/j.ijcard.2017.08.004 [doi]
AB  - BACKGROUND: Hyponatremia is a well-known risk factor for worse outcomes in heart 
      failure (HF) patients. The impact of hyponatremia according to the ejection
      fraction (EF) is unclear. We evaluated the prognostic value of hyponatremia
      according to HF type. METHODS AND RESULTS: The Korea Acute Heart Failure (KorAHF)
      registry consecutively enrolled 5625 patients. Hyponatremia was defined as serum 
      sodium level<135mmol/L at hospital admission. HF with preserved and reduced
      ejection fraction were defined as an LVEF >/=50% and LVEF </=40%, respectively.
      Among 5103 patients with available EF, 2088 (60%) had HFrEF, and 1284 (25%) had
      HFpEF. There was no difference in serum sodium level between the groups (HFrEF:
      137.4+/-4.7mmol/L vs. HFpEF: 137.5+/-5.0mmol/L, P=0.710). Hyponatremic patients
      had higher in-hospital mortality or urgent heart transplantation in all (11.3%
      vs. 4.5%, P<0.001), in HFrEF (13.1% vs. 4.9%, P<0.001), and in HFpEF (6.0% vs.
      1.9%, P<0.001). After adjustment for significant covariates, hyponatremia was
      associated with 1.5 fold increased risk for 1-year post-discharge death in the
      HFrEF group (HR, 1.52; 95% CI, 1.24-1.86), but not in the HFpEF group (HR, 1.16; 
      95% CI, 0.84-1.61). During admission, the sodium status changed in 22% of the
      patients and the discharge sodium status had greater prognostic value.
      CONCLUSIONS: Hyponatremia is independent of HF type. Hyponatremia is a
      significant risk factor for adverse in-hospital outcomes; however its long-term
      prognostic value is only limited to patients with HFrEF, but not for those with
      HFpEF.
CI  - Copyright (c) 2017 Elsevier Ireland Ltd. All rights reserved.
FAU - Park, Jin Joo
AU  - Park JJ
AD  - Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
FAU - Cho, Young-Jin
AU  - Cho YJ
AD  - Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
FAU - Oh, Il-Young
AU  - Oh IY
AD  - Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
FAU - Park, Hyun-Ah
AU  - Park HA
AD  - Department of Family Medicine, Inje University Seoul Paik Hospital, Seoul,
      Republic of Korea.
FAU - Lee, Hae-Young
AU  - Lee HY
AD  - Department of Internal Medicine, Seoul National University Hospital, Seoul,
      Republic of Korea.
FAU - Kim, Kye Hun
AU  - Kim KH
AD  - Heart Research Center of Chonnam National University, Gwangju, Republic of Korea.
FAU - Yoo, Byung-Su
AU  - Yoo BS
AD  - Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
FAU - Kang, Seok-Min
AU  - Kang SM
AD  - Yonsei University College of Medicine, Seoul, Republic of Korea.
FAU - Baek, Sang Hong
AU  - Baek SH
AD  - The Catholic University of Korea, Seoul, Republic of Korea.
FAU - Jeon, Eun-Seok
AU  - Jeon ES
AD  - Sungkyunkwan University College of Medicine, Seoul, Republic of Korea.
FAU - Kim, Jae-Joong
AU  - Kim JJ
AD  - University of Ulsan College of Medicine, Seoul, Republic of Korea.
FAU - Cho, Myeong-Chan
AU  - Cho MC
AD  - Chungbuk National University College of Medicine, Cheongju, Republic of Korea.
FAU - Chae, Shung Chull
AU  - Chae SC
AD  - Kyungpook National University College of Medicine, Daegu, Republic of Korea.
FAU - Oh, Byung-Hee
AU  - Oh BH
AD  - Department of Internal Medicine, Seoul National University Hospital, Seoul,
      Republic of Korea.
FAU - Choi, Dong-Ju
AU  - Choi DJ
AD  - Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
      Electronic address: [email protected]
LA  - eng
PT  - Journal Article
DEP - 20170805
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
OTO - NOTNLM
OT  - Heart failure with preserved ejection fraction
OT  - Heart failure with reduced ejection fraction
OT  - Hyponatremia
OT  - Prognosis
EDAT- 2017/08/20 06:00
MHDA- 2017/08/20 06:00
CRDT- 2017/08/20 06:00
PHST- 2017/06/17 [received]
PHST- 2017/07/20 [revised]
PHST- 2017/08/03 [accepted]
AID - S0167-5273(17)33597-0 [pii]
AID - 10.1016/j.ijcard.2017.08.004 [doi]
PST - aheadofprint
SO  - Int J Cardiol. 2017 Aug 5. pii: S0167-5273(17)33597-0. doi:
      10.1016/j.ijcard.2017.08.004.