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A cluster randomised control trial of a multi-component weight management programme for adults with intellectual disabilities and obesity.

Abstract There have been few published controlled studies of multi-component weight management programmes that include an energy deficit diet (EDD), for adults with intellectual disabilities and obesity. The objective of this study was to conduct a single-blind, cluster randomised controlled trial comparing a multi-component weight management programme to a health education programme. Participants were randomised to either TAKE 5, which included an EDD or Waist Winners Too (WWToo), based on health education principles. Outcomes measured at baseline, 6 months (after a weight loss phase) and 12 months (after a 6-month weight maintenance phase), by a researcher blinded to treatment allocation, included: weight; BMI; waist circumference; physical activity; sedentary behaviour and health-related quality of life. The recruitment strategy was effective with fifty participants successfully recruited. Both programmes were acceptable to adults with intellectual disabilities, evidenced by high retention rates (90 %). Exploratory efficacy analysis revealed that at 12 months there was a trend for more participants in TAKE 5 (50·0 %) to achieve a clinically important weight loss of 5-10 %, in comparison to WWToo (20·8 %) (OR 3·76; 95 % CI 0·92, 15·30; 0·064). This study found that a multi-component weight management programme that included an EDD, is feasible and an acceptable approach to weight loss when tailored to meet the needs of adults with intellectual disabilities and obesity.
PMID
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Authors

Mayor MeshTerms

Body Weight

Weight Reduction Programs

Keywords

EDD

EQ-5D

European Quality of Life-5 dimensions

IPAQ-S

International Physical Activity Questionnaire-Short

QOL

WWToo

Waist Winners Too

energy deficit diet

quality of life

Intellectual disabilities

Obesity

TAKE 5

Weight management

Journal Title the british journal of nutrition
Publication Year Start




PMID- 28831953
OWN - NLM
STAT- MEDLINE
DA  - 20170823
DCOM- 20170907
LR  - 20170907
IS  - 1475-2662 (Electronic)
IS  - 0007-1145 (Linking)
VI  - 118
IP  - 3
DP  - 2017 Aug
TI  - A cluster randomised control trial of a multi-component weight management
      programme for adults with intellectual disabilities and obesity.
PG  - 229-240
LID - 10.1017/S0007114517001933 [doi]
AB  - There have been few published controlled studies of multi-component weight
      management programmes that include an energy deficit diet (EDD), for adults with 
      intellectual disabilities and obesity. The objective of this study was to conduct
      a single-blind, cluster randomised controlled trial comparing a multi-component
      weight management programme to a health education programme. Participants were
      randomised to either TAKE 5, which included an EDD or Waist Winners Too (WWToo), 
      based on health education principles. Outcomes measured at baseline, 6 months
      (after a weight loss phase) and 12 months (after a 6-month weight maintenance
      phase), by a researcher blinded to treatment allocation, included: weight; BMI;
      waist circumference; physical activity; sedentary behaviour and health-related
      quality of life. The recruitment strategy was effective with fifty participants
      successfully recruited. Both programmes were acceptable to adults with
      intellectual disabilities, evidenced by high retention rates (90 %). Exploratory 
      efficacy analysis revealed that at 12 months there was a trend for more
      participants in TAKE 5 (50.0 %) to achieve a clinically important weight loss of 
      5-10 %, in comparison to WWToo (20.8 %) (OR 3.76; 95 % CI 0.92, 15.30; 0.064).
      This study found that a multi-component weight management programme that included
      an EDD, is feasible and an acceptable approach to weight loss when tailored to
      meet the needs of adults with intellectual disabilities and obesity.
FAU - Harris, Leanne
AU  - Harris L
AD  - 1College of Medical Veterinary and Life Sciences,Institute of Mental Health &
      Wellbeing,University of Glasgow,Glasgow G12 0XH,UK.
FAU - Hankey, Catherine
AU  - Hankey C
AD  - 2College of Medical Veterinary and Life Sciences,Institute of Health &
      Wellbeing,University of Glasgow,Glasgow G31 2ER,UK.
FAU - Jones, Nathalie
AU  - Jones N
AD  - 1College of Medical Veterinary and Life Sciences,Institute of Mental Health &
      Wellbeing,University of Glasgow,Glasgow G12 0XH,UK.
FAU - Pert, Carol
AU  - Pert C
AD  - 3Learning Disability Psychology, National Health Service (NHS) Greater Glasgow
      and Clyde,Glasgow G52 2HH,UK.
FAU - Murray, Heather
AU  - Murray H
AD  - 4Robertson Centre for Biostatistics,Institute of Health and Wellbeing,University 
      of Glasgow,Glasgow G12 8QQ,UK.
FAU - Tobin, Janet
AU  - Tobin J
AD  - 5Glasgow City Community Health Partnership (CHP) North East Sector,Eastbank
      Conference Training Centre,Glasgow G32 9AA,UK.
FAU - Boyle, Susan
AU  - Boyle S
AD  - 6Glasgow and Clyde Weight Management Service,Glasgow G3 8SJ,UK.
FAU - Melville, Craig
AU  - Melville C
AD  - 1College of Medical Veterinary and Life Sciences,Institute of Mental Health &
      Wellbeing,University of Glasgow,Glasgow G12 0XH,UK.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - England
TA  - Br J Nutr
JT  - The British journal of nutrition
JID - 0372547
SB  - IM
MH  - Adult
MH  - Body Mass Index
MH  - *Body Weight
MH  - Diet
MH  - Exercise
MH  - Feasibility Studies
MH  - Female
MH  - Health Behavior
MH  - Health Education
MH  - Humans
MH  - Intellectual Disability/*complications
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Obesity/*therapy
MH  - Pilot Projects
MH  - Quality of Life
MH  - Single-Blind Method
MH  - Treatment Outcome
MH  - Waist Circumference
MH  - *Weight Reduction Programs
OTO - NOTNLM
OT  - EDD
OT  - EQ-5D
OT  - European Quality of Life-5 dimensions
OT  - IPAQ-S
OT  - International Physical Activity Questionnaire-Short
OT  - QOL
OT  - WWToo
OT  - Waist Winners Too
OT  - energy deficit diet
OT  - quality of life
OT  - Intellectual disabilities
OT  - Obesity
OT  - TAKE 5
OT  - Weight management
EDAT- 2017/08/24 06:00
MHDA- 2017/09/08 06:00
CRDT- 2017/08/24 06:00
AID - S0007114517001933 [pii]
AID - 10.1017/S0007114517001933 [doi]
PST - ppublish
SO  - Br J Nutr. 2017 Aug;118(3):229-240. doi: 10.1017/S0007114517001933.