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Endobronchial melanoma metastasis 40 years after the excision of the primary cutaneous tumor: A case report.

Abstract Endobronchial melanoma metastases are rare, comprising 4.5% of all endobronchial metastases. They are diagnosed at a median time of 48 months from primary tumor presentation, and survival of these patients is poorer when accompanied by other metastatic sites or malignant pleural effusion. We present a case of endobronchial melanoma metastasis happening 40 years after the initial diagnosis. The need of adjuvant techniques in the diagnosis of this tumor is highlighted and a short review on this rare phenomenon is provided.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 28834918
OWN - NLM
STAT- In-Process
DA  - 20170823
LR  - 20170907
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 34
DP  - 2017 Aug
TI  - Endobronchial melanoma metastasis 40 years after the excision of the primary
      cutaneous tumor: A case report.
PG  - e7931
LID - 10.1097/MD.0000000000007931 [doi]
AB  - RATIONALE: Endobronchial melanoma metastases are rare, comprising 4.5% of all
      endobronchial metastases. They are diagnosed at a median time of 48 months from
      primary tumor presentation, and survival of these patients is poorer when
      accompanied by other metastatic sites or malignant pleural effusion. We present a
      case of endobronchial melanoma metastasis happening 40 years after the initial
      diagnosis. The need of adjuvant techniques in the diagnosis of this tumor is
      highlighted and a short review on this rare phenomenon is provided. PATIENTS
      CONCERNS: An 83-year old nonsmoking woman, presented with dyspnea. DIAGNOSES:
      Left lung atelectasis was found. INTERVENTIONS: Endobronchial resection of a
      tumor of the left main stem bronchus was achieved by rigid bronchoscopy under
      general anesthesia with complete reventilation of the left lung. OUTCOMES:
      Histopathological, immunohistochemical and molecular diagnostics of the resected 
      tumor led to a diagnosis of an endobronchial melanoma metastasis. LESSONS:
      Melanoma is a type of tumor that cannot be regarded as cured even after long
      disease-free periods, and thus, any new symptomatology in these patients warrants
      stringent work up.
FAU - Karpathiou, Georgia
AU  - Karpathiou G
AD  - aDepartment of Pathology bDepartment of Chest Disease and Thoracic Oncology,
      North Hospital, University Hospital of St-Etienne, France.
FAU - Froudarakis, Marios
AU  - Froudarakis M
FAU - Da Cruz, Vanessa
AU  - Da Cruz V
FAU - Forest, Fabien
AU  - Forest F
FAU - Sauvage, Maxime
AU  - Sauvage M
FAU - Vergnon, Jean Michel
AU  - Vergnon JM
FAU - Peoc'h, Michel
AU  - Peoc'h M
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
PMC - PMC5572040
EDAT- 2017/08/24 06:00
MHDA- 2017/08/24 06:00
CRDT- 2017/08/24 06:00
AID - 10.1097/MD.0000000000007931 [doi]
AID - 00005792-201708250-00055 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Aug;96(34):e7931. doi: 10.1097/MD.0000000000007931.