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Mycoplasma genitalium From Basic Science to Public Health: Summary of the Results From a National Institute of Allergy and Infectious Disesases Technical Consultation and Consensus Recommendations for Future Research Priorities.

Abstract This article lays out the research priorities for Mycoplasma genitalium research agreed upon by the participants in a 2016 National Institutes of Allergy and Infectious Diseases-funded Technical Consultation focused on this organism. The state of current knowledge concerning the microbiology, epidemiology, clinical manifestations of infection, treatment, and public health significance of M. genitalium reviewed at the meeting is described in detail in the individual articles included in this supplemental edition of the Journal of Infectious Diseases. Here we summarize the points made in these articles most relevant to the formulation of the research priorities listed in this article. The most important recommendation resulting from this Technical Consultation is the initiation of clinical trials designed to determine definitively whether screening for and treatment of M. genitalium infections in women and their sexual partners improve reproductive health in women and/or prevent human immunodeficiency virus transmission.
PMID
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Authors

Mayor MeshTerms

Mycoplasma genitalium

Keywords

HIV infection

Mycoplasma genitalium

antibiotic resistance

clinical trials

diagnosis

Journal Title the journal of infectious diseases
Publication Year Start




PMID- 28838075
OWN - NLM
STAT- MEDLINE
DA  - 20170825
DCOM- 20170905
LR  - 20170906
IS  - 1537-6613 (Electronic)
IS  - 0022-1899 (Linking)
VI  - 216
IP  - suppl_2
DP  - 2017 Jul 15
TI  - Mycoplasma genitalium From Basic Science to Public Health: Summary of the Results
      From a National Institute of Allergy and Infectious Disesases Technical
      Consultation and Consensus Recommendations for Future Research Priorities.
PG  - S427-S430
LID - 10.1093/infdis/jix147 [doi]
AB  - This article lays out the research priorities for Mycoplasma genitalium research 
      agreed upon by the participants in a 2016 National Institutes of Allergy and
      Infectious Diseases-funded Technical Consultation focused on this organism. The
      state of current knowledge concerning the microbiology, epidemiology, clinical
      manifestations of infection, treatment, and public health significance of M.
      genitalium reviewed at the meeting is described in detail in the individual
      articles included in this supplemental edition of the Journal of Infectious
      Diseases. Here we summarize the points made in these articles most relevant to
      the formulation of the research priorities listed in this article. The most
      important recommendation resulting from this Technical Consultation is the
      initiation of clinical trials designed to determine definitively whether
      screening for and treatment of M. genitalium infections in women and their sexual
      partners improve reproductive health in women and/or prevent human
      immunodeficiency virus transmission.
CI  - (c) The Author 2017. Published by Oxford University Press for the Infectious
      Diseases Society of America. All rights reserved. For permissions, e-mail:
      [email protected]
FAU - Martin, David H
AU  - Martin DH
AD  - Department of Epidemiology, Tulane University School of Public Health.
AD  - Department of Internal Medicine, Section of Infectious Diseases, Louisiana State 
      University Health Sciences Center, New Orleans.
FAU - Manhart, Lisa E
AU  - Manhart LE
AD  - Departments of Epidemiology.
AD  - Global Health, Center for AIDS and STD, University of Washington, Seattle.
FAU - Workowski, Kimberly A
AU  - Workowski KA
AD  - Department of Medicine, Division of Infectious Diseases, Emory University,
      Atlanta, Georgia.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - J Infect Dis
JT  - The Journal of infectious diseases
JID - 0413675
RN  - 0 (Anti-Bacterial Agents)
SB  - AIM
SB  - IM
MH  - Adult
MH  - Anti-Bacterial Agents/therapeutic use
MH  - Clinical Trials as Topic
MH  - Consensus
MH  - Drug Resistance, Microbial
MH  - Female
MH  - HIV Infections/prevention & control/transmission
MH  - Humans
MH  - Mycoplasma Infections/*diagnosis/drug therapy/*epidemiology
MH  - *Mycoplasma genitalium
MH  - National Institutes of Health (U.S.)
MH  - Practice Guidelines as Topic
MH  - Public Health/*trends
MH  - Research/*trends
MH  - United States
OTO - NOTNLM
OT  - HIV infection
OT  - Mycoplasma genitalium
OT  - antibiotic resistance
OT  - clinical trials
OT  - diagnosis
EDAT- 2017/08/26 06:00
MHDA- 2017/09/07 06:00
CRDT- 2017/08/26 06:00
AID - 4040969 [pii]
AID - 10.1093/infdis/jix147 [doi]
PST - ppublish
SO  - J Infect Dis. 2017 Jul 15;216(suppl_2):S427-S430. doi: 10.1093/infdis/jix147.