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Variations and Trends in Health Burden of Visual Impairment Due to Cataract: A Global Analysis.

Abstract To evaluate the global trends in health burden of people visually impaired from cataract in terms of disability-adjusted life years (DALY) and its correlations with national levels of socioeconomic development.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title investigative ophthalmology & visual science
Publication Year Start




PMID- 28846778
OWN - NLM
STAT- MEDLINE
DA  - 20170828
DCOM- 20170904
LR  - 20170904
IS  - 1552-5783 (Electronic)
IS  - 0146-0404 (Linking)
VI  - 58
IP  - 10
DP  - 2017 Aug 01
TI  - Variations and Trends in Health Burden of Visual Impairment Due to Cataract: A
      Global Analysis.
PG  - 4299-4306
LID - 10.1167/iovs.17-21459 [doi]
AB  - Purpose: To evaluate the global trends in health burden of people visually
      impaired from cataract in terms of disability-adjusted life years (DALY) and its 
      correlations with national levels of socioeconomic development. Methods: Global, 
      regional, and national DALY numbers, crude rate, and age-standardized rate of
      cataract vision loss by age and sex were obtained from the database of the Global
      Burden of Disease Study 2015. The human development index, per capita gross
      domestic product, and other country-level data were derived from international
      open databases. Regression analysis was used to assess the correlations between
      age-standardized DALY rate and socioeconomic variables. Results: The global DALY 
      numbers of cataract vision loss increased by 89.42%, from 2048.18 (95%CI
      [confidence interval]: 1457.60-2761.80) thousands in 1990 to 3879.74 (95% CI:
      2766.07-5232.43) thousands in 2015 (P < 0.001). Females had higher DALY number
      315.83 (95%CI: 237.17-394.4) and crude rate 38.29 (95%CI: 35.35-41.23) after
      adjusting for age and country (all P < 0.001). The age-standardized DALY rate was
      higher in countries with low human development index (HDI), with 91.03 (95%CI:
      73.04-108.75) for low HDI, 81.67 (95%CI: 53.24-108.82) for medium HDI, 55.89
      (95%CI: 36.87-69.63) for high HDI, and 17.10 (95%CI: 13.91-26.84) for very high
      HDI countries (P < 0.01), respectively. The national age-standardized DALY rates 
      in 2015 were negatively associated with both HDI (R2 = 0.489, P < 0.001) and per 
      capita gross domestic product (R2 = 0.331, P < 0.001). Stepwise multiple
      regression showed that HDI was significantly correlated with national
      age-standardized DALY rates in 2015 after adjusting for other confounding factors
      (P < 0.001). Conclusions: The global health burden of vision loss due to cataract
      increased between 1990 and 2015 despite considerable efforts from the World
      Health Organization and VISION 2020 initiatives.
FAU - He, Miao
AU  - He M
AD  - Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen
      University, Guangzhou, People's Republic of China.
FAU - Wang, Wei
AU  - Wang W
AD  - Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen
      University, Guangzhou, People's Republic of China.
FAU - Huang, Wenyong
AU  - Huang W
AD  - Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen
      University, Guangzhou, People's Republic of China.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Invest Ophthalmol Vis Sci
JT  - Investigative ophthalmology & visual science
JID - 7703701
SB  - IM
MH  - Adult
MH  - Age Distribution
MH  - Aged
MH  - Aged, 80 and over
MH  - Cataract/*epidemiology
MH  - Female
MH  - Global Health/*trends
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Quality-Adjusted Life Years
MH  - Sex Distribution
MH  - Socioeconomic Factors
MH  - Vision Disorders/*epidemiology
MH  - Visually Impaired Persons/*statistics & numerical data
MH  - World Health Organization
MH  - Young Adult
EDAT- 2017/08/29 06:00
MHDA- 2017/09/05 06:00
CRDT- 2017/08/29 06:00
AID - 2652822 [pii]
AID - 10.1167/iovs.17-21459 [doi]
PST - ppublish
SO  - Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):4299-4306. doi:
      10.1167/iovs.17-21459.