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PMID- 28852728
OWN - NLM
STAT- MEDLINE
DA  - 20170830
DCOM- 20170908
LR  - 20170908
IS  - 2505-0044 (Electronic)
IS  - 2505-0044 (Linking)
VI  - 13
IP  - 4
DP  - 2016
TI  - MEDICINAL HERBS USED BY HIV-POSITIVE PEOPLE IN LESOTHO.
PG  - 123-131
LID - 10.21010/ajtcam.v13i4.17 [doi]
AB  - BACKGROUND: The use of medicinal herbs whose efficacy and toxicities are not
      known by HIV-positive people in Lesotho is a threat to the effectiveness of
      antiretroviral treatment. This study explored some medicinal herbs used by
      HIV-positive people in Lesotho and the reasons for their use. METHODS: This was a
      cross sectional study based on a questionnaire distributed to purposively-sampled
      HIV-positive people in Leribe and Maseru districts of Lesotho. The participants' 
      socio-demographic and clinical variables were summarized using frequency tables
      in Stata version 13 statistical software. Data variables for medicinal herbs
      used, frequency of use, uses by the participants and in the literature, parts of 
      plants used and the method of preparation were also explored. RESULTS: Out of 400
      questionnaires distributed to the participants, 389 were returned with data
      acceptable for analysis. Ages of the participants ranged from 18 to 75 years
      (Mean=43 + 11.6). Out of the 272 (69.9%) participants who conceded that they had 
      used medicinal herbs at least once, 30 (7.7%) participants used medicinal herbs
      frequently while 242 (62.2 %) rarely used the herbs. At least 20 plant species
      belonging to 16 families were reportedly used by the participants. Asteraceae was
      the most common plant family reportedly used by the participants. Allium sativum 
      and Dicoma anomala, reportedly used by 21.0% and 14.3% respectively, were the
      most commonly used medicinal herbs in this population. In addition, boosting the 
      immune system and treating gastrointestinal ailments, apparently cited by 32% and
      28% participants respectively, were the most commonly reported reasons for using 
      medicinal herbs. CONCLUSION: A considerable proportion (69.9%) of HIV-positive
      people use medicinal herbs in this population, and 7.7% use them frequently. At
      least 20 plant species belonging to 16 families were reportedly used by the
      participants. HIV counselling protocols in Lesotho should emphasize the dangers
      of using medicinal herbs whose safety and compatibility with antiretroviral drugs
      is not known. The efficacy and toxicity profiles of the medicinal plants
      identified in this study need to be investigated. Furthermore, the effects of
      these plants on antiretroviral treatment outcomes including herb-drug
      interactions need to be explored.
FAU - Mugomeri, Eltony
AU  - Mugomeri E
AD  - Eltony Mugomeri (MTech. Biomedical Technology) Department of Pharmacy, National
      University of Lesotho, Faculty of Health Sciences, Roma Campus, P.O. Roma 180,
      Maseru, Lesotho.
FAU - Chatanga, Peter
AU  - Chatanga P
AD  - Peter Chatanga (MSc. Tropical Resource Ecology) Department of Biology, National
      University of Lesotho, Faculty of Science and Technology, Roma Campus, P.O. Roma 
      180, Maseru, Lesotho.
FAU - Chakane, Ntema
AU  - Chakane N
AD  - Ntema Chakane (BSc. Nursing and Midwifery)Department of Nursing, National
      University of Lesotho, Faculty of Health Sciences, Roma Campus, P.O. Roma 180,
      Maseru, Lesotho.
LA  - eng
PT  - Journal Article
DEP - 20160703
PL  - Nigeria
TA  - Afr J Tradit Complement Altern Med
JT  - African journal of traditional, complementary, and alternative medicines : AJTCAM
JID - 101232990
RN  - 0 (Plant Extracts)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Cross-Sectional Studies
MH  - Ethnobotany
MH  - Female
MH  - HIV Infections/*drug therapy
MH  - Humans
MH  - Lesotho
MH  - Male
MH  - Middle Aged
MH  - Plant Extracts/*administration & dosage
MH  - Plants, Medicinal/*chemistry
MH  - Young Adult
PMC - PMC5566135
OTO - NOTNLM
OT  - Allium sativum
OT  - Anti-retroviral treatment
OT  - Dicoma anomala
OT  - HIV
OT  - Herb-drug interaction
OT  - Medicinal herb
EDAT- 2017/08/31 06:00
MHDA- 2017/09/09 06:00
CRDT- 2017/08/31 06:00
AID - 10.21010/ajtcam.v13i4.17 [doi]
AID - AJTCAM-13-123 [pii]
PST - epublish
SO  - Afr J Tradit Complement Altern Med. 2016 Jul 3;13(4):123-131. doi:
      10.21010/ajtcam.v13i4.17. eCollection 2016.