PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.




PMID- 28852735
OWN - NLM
STAT- MEDLINE
DA  - 20170830
DCOM- 20170908
LR  - 20170908
IS  - 2505-0044 (Electronic)
IS  - 2505-0044 (Linking)
VI  - 13
IP  - 4
DP  - 2016
TI  - INHIBITORY EFFECT OF LYCOPENE AGAINST THE GROWTH OF HUMAN GASTRIC CANCER CELLS.
PG  - 184-190
LID - 10.21010/ajtcam.v13i4.24 [doi]
AB  - BACKGROUND: The aim of this study was to investigate the anti-proliferative
      effect of Lycopene on HGC-27 cells. MATERIALS AND METHODS: HGC-27 cells were
      treated with varying concentration lycopene for 24, 48, 72 h. The cell growth
      inhibition was analyzed by MTT. Western blotting was used to indicate changes in 
      the levels of LC3-I, LC3-II, ERK (extracellular signal-regulated protein kinase) 
      and phosphorylation-ERK (p-ERK). RESULTS: Lycopene displayed antiproliferative
      activity in HGC-27 cell lines. Western blotting showed that Lycopene
      significantly enhanced LC3-I, p-ERK proteins expression. In gastric cancer nude
      mice model, lycopene treatment significantly decreased tumour weight. These
      findings indicated that lycopene treatment induces the anti-proliferation of
      HGC-27 cells. CONCLUSION: Lycopene treatment inhibited HGC-27 cells growth by
      activating ERK.
FAU - Zhou, ShenKang
AU  - Zhou S
AD  - Department of Gastrointestinal surgery, Taizhou hospital, TaiZhou city, Zhejiang,
      china.
FAU - Zhang, RuiLi
AU  - Zhang R
AD  - Department of Gastrointestinal surgery, Taizhou hospital, TaiZhou city, Zhejiang,
      china.
FAU - Bi, TieNan
AU  - Bi T
AD  - Department of Gastrointestinal surgery, Taizhou hospital, TaiZhou city, Zhejiang,
      china.
FAU - Lu, Yong
AU  - Lu Y
AD  - Department of Gastrointestinal surgery, Taizhou hospital, TaiZhou city, Zhejiang,
      china.
FAU - Jiang, LiangXian
AU  - Jiang L
AD  - Department of Gastrointestinal surgery, Taizhou hospital, TaiZhou city, Zhejiang,
      china.
LA  - eng
PT  - Journal Article
DEP - 20160703
PL  - Nigeria
TA  - Afr J Tradit Complement Altern Med
JT  - African journal of traditional, complementary, and alternative medicines : AJTCAM
JID - 101232990
RN  - 0 (MAP1LC3 protein, mouse)
RN  - 0 (Microtubule-Associated Proteins)
RN  - 36-88-4 (Carotenoids)
RN  - EC 2.7.11.24 (Extracellular Signal-Regulated MAP Kinases)
RN  - SB0N2N0WV6 (lycopene)
SB  - IM
MH  - Animals
MH  - Apoptosis/drug effects
MH  - Carotenoids/*administration & dosage
MH  - Cell Cycle/drug effects
MH  - Cell Line, Tumor
MH  - Cell Proliferation/drug effects
MH  - Extracellular Signal-Regulated MAP Kinases/genetics/metabolism
MH  - Humans
MH  - Male
MH  - Mice
MH  - Mice, Inbred BALB C
MH  - Mice, Nude
MH  - Microtubule-Associated Proteins/genetics/metabolism
MH  - Stomach Neoplasms/*drug therapy/genetics/metabolism/physiopathology
PMC - PMC5566143
OTO - NOTNLM
OT  - Apoptosis
OT  - HGC-27
OT  - gastric cancer
OT  - p-ERK
EDAT- 2017/08/31 06:00
MHDA- 2017/09/09 06:00
CRDT- 2017/08/31 06:00
AID - 10.21010/ajtcam.v13i4.24 [doi]
AID - AJTCAM-13-184 [pii]
PST - epublish
SO  - Afr J Tradit Complement Altern Med. 2016 Jul 3;13(4):184-190. doi:
      10.21010/ajtcam.v13i4.24. eCollection 2016.