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BMI is a key risk factor for early periprosthetic joint infection following total hip and knee arthroplasty.

Abstract To identify patient and surgical risk factors that are associated with periprosthetic joint infection (PJI), especially whether obesity is a risk factor following total hip arthroplasty (THA) and total knee arthroplasty (TKA).
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title the new zealand medical journal
Publication Year Start




PMID- 28859063
OWN - NLM
STAT- In-Process
DA  - 20170831
LR  - 20170831
IS  - 1175-8716 (Electronic)
IS  - 0028-8446 (Linking)
VI  - 130
IP  - 1461
DP  - 2017 Sep 01
TI  - BMI is a key risk factor for early periprosthetic joint infection following total
      hip and knee arthroplasty.
PG  - 24-34
AB  - AIM: To identify patient and surgical risk factors that are associated with
      periprosthetic joint infection (PJI), especially whether obesity is a risk factor
      following total hip arthroplasty (THA) and total knee arthroplasty (TKA).
      METHODS: New Zealand Surgical Site Infection Improvement Programme data was
      analysed using deep infection within 90 days of the index procedure as the
      outcome. This was tested against surgical and patient factors for statistical
      associations in a multivariate model. RESULTS: A total of 10,690 primary THAs and
      9,481 primary TKAs were recorded by the NZSSIIP between 2013 and 2015.
      Multivariate analysis showed statistically significant associations with deep
      infections for BMI (BMI >40kg/m2 OR 5.62, 95% CI 2.25-14.0), male gender (OR 1.7,
      95% CI 1.05-2.74) and age greater than 75 for THAs (age <55 years OR 0.35, 95% CI
      0.14-0.87). For TKAs, multivariate analysis showed statistically significant
      associations with deep infection for BMI (BMI >40kg/m2 OR 1.94, 95% CI:
      0.63-5.70) and male gender (OR 2.96, 95% CI 1.51-5.80). CONCLUSIONS: These
      findings show that obesity is one of the most important modifiable patient
      factors in predicting PJI following THA and TKA.
FAU - Jung, Patrick
AU  - Jung P
AD  - Medical Student, School of Medicine, University of Auckland, Auckland.
FAU - Morris, Arthur J
AU  - Morris AJ
AD  - Clinical Microbiologist, Auckland City Hospital, Clinical Lead for the Health
      Quality and Safety Commission's NZ SSIIP.
FAU - Zhu, Mark
AU  - Zhu M
AD  - Fellow in Surgery, School of Medicine, University of Auckland, Auckland.
FAU - Roberts, Sally A
AU  - Roberts SA
AD  - Clinical Microbiologist, Auckland City Hospital, Clinical Lead for the Health
      Quality and Safety Commission's Infection Prevention and Control Programmes.
FAU - Frampton, Chris
AU  - Frampton C
AD  - Statistician, Dept of Orthopaedic Surgery & Musculoskeletal Medicine, University 
      of Otago.
FAU - Young, Simon W
AU  - Young SW
AD  - Consultant Orthopaedic Surgeon, Department of Orthopaedics, North Shore Hospital.
LA  - eng
PT  - Journal Article
DEP - 20170901
PL  - New Zealand
TA  - N Z Med J
JT  - The New Zealand medical journal
JID - 0401067
COI - Dr Morris is the Clinical Lead for the NZ Surgical Site Infection Improvement
      Programme.
EDAT- 2017/09/01 06:00
MHDA- 2017/09/01 06:00
CRDT- 2017/09/01 06:00
PST - epublish
SO  - N Z Med J. 2017 Sep 1;130(1461):24-34.