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Effects of acupoint-stimulation for the treatment of primary dysmenorrhoea compared with NSAIDs: a systematic review and meta-analysis of 19 RCTs.

Abstract Primary dysmenorrhoea (PD), defined as painful menses in women with normal pelvic anatomy, is one of the most common gynaecological syndromes. Acupoint-stimulation could potentially be an effective intervention for PD. Our aim was to determine the effectiveness of acupoint-stimulation compared with Non-Steroidal Anti-Inflammatory Drugs (NASIDs) in the treatment of PD.
PMID
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Authors

Mayor MeshTerms

Acupuncture Therapy

Keywords

Acupoint-stimulation

Meta-analysis

Non-steroidal anti-inflammatory drugs

Primary dysmenorrhoea

Systematic review

Journal Title bmc complementary and alternative medicine
Publication Year Start




PMID- 28859645
OWN - NLM
STAT- MEDLINE
DA  - 20170901
DCOM- 20170908
LR  - 20170908
IS  - 1472-6882 (Electronic)
IS  - 1472-6882 (Linking)
VI  - 17
IP  - 1
DP  - 2017 Aug 31
TI  - Effects of acupoint-stimulation for the treatment of primary dysmenorrhoea
      compared with NSAIDs: a systematic review and meta-analysis of 19 RCTs.
PG  - 436
LID - 10.1186/s12906-017-1924-8 [doi]
AB  - BACKGROUND: Primary dysmenorrhoea (PD), defined as painful menses in women with
      normal pelvic anatomy, is one of the most common gynaecological syndromes.
      Acupoint-stimulation could potentially be an effective intervention for PD. Our
      aim was to determine the effectiveness of acupoint-stimulation compared with
      Non-Steroidal Anti-Inflammatory Drugs (NASIDs) in the treatment of PD. METHODS:
      Six databases were searched to December 2014. Sixteen studies involving 1679 PD
      patients were included. We included randomized controlled trials that compared
      acupoint-stimulation with NASIDs for the treatment of PD. The main outcomes
      assessed were clinical effectiveness rate, symptom score, visual analogue score, 
      variation in peripheral blood prostaglandin F2alpha (PGF2alpha) and side effects.
      All analyses were performed using Comprehensive Meta-Analysis statistical
      software. RESULTS: (1) The total efficacy was better than control group: odds
      ratio = 5.57; 95% confidence interval (95% CI) = 3.96, 7.83; P < 0.00001; (2) The
      effect of intervention was positive in relieving the severity of PD symptoms:
      mean difference (MD) = 2.99; 95%CI = 2.49, 3.49; P < 0.00001; (3) No statistical 
      difference existed between two groups in terms of a reduction in the VAS: MD =
      1.24; 95%CI = -3.37, 5.85; P = 0.60; (4) The effect of intervention on the
      variation in peripheral blood PGF2alpha between two groups was positive: MD =
      7.55; 95%CI = 4.29,10.82; P < 0.00001; (5) The side effects of control groups was
      more than the acupoint-stimulation group: OR = 0.03; 95%CI =0.00,0.22; P =
      0.0005. CONCLUSIONS: According to this article, acupoint-stimulation can relieve 
      pain effectively in the treatment of PD and offers advantages in increasing the
      overall effectiveness.
FAU - Xu, Yang
AU  - Xu Y
AD  - Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin,
      300193, China.
AD  - Department of Gynecology and Obstetrics, Nankai Hospital, Tianjin Academy of
      Integrative Medicine, Tianjin, 300100, China.
FAU - Zhao, Wenli
AU  - Zhao W
AD  - Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin,
      300193, China.
AD  - Department of Neurology, Nankai Hospital, Tianjin Academy of Integrative
      Medicine, Tianjin, 300100, China.
FAU - Li, Te
AU  - Li T
AD  - Department of Chinese Medicine, Tianjin Hearing Impairment Specialist Hospital,
      Tianjin, 300150, China.
FAU - Bu, Huaien
AU  - Bu H
AD  - Department of Public Health, School of Chinese Medicine, Tianjin University of
      Traditional Chinese Medicine, Tianjin, 300193, China.
FAU - Zhao, Zhimei
AU  - Zhao Z
AD  - Department of Gynecology and Obstetrics of Chinese Medicine, First Teaching
      Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, 
      China.
FAU - Zhao, Ye
AU  - Zhao Y
AD  - Department of Chemical Engineering, University of Florida, 1006 Center Drive,
      Gainesville, FL, 32611, USA. [email protected]
AD  - Institute for Cell & Tissue Science and Engineering, University of Florida,
      Gainesville, FL, 32611, USA. [email protected]
FAU - Song, Shilin
AU  - Song S
AD  - Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of
      Traditional Chinese Medicine, No. 88 Yu Quan Road, Nankai District, Tianjin,
      300193, China. [email protected]
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
DEP - 20170831
PL  - England
TA  - BMC Complement Altern Med
JT  - BMC complementary and alternative medicine
JID - 101088661
RN  - 0 (Anti-Inflammatory Agents, Non-Steroidal)
SB  - IM
MH  - Acupuncture Points
MH  - *Acupuncture Therapy
MH  - Anti-Inflammatory Agents, Non-Steroidal/*administration & dosage
MH  - Dysmenorrhea/drug therapy/*therapy
MH  - Female
MH  - Humans
MH  - Male
MH  - Randomized Controlled Trials as Topic
PMC - PMC5580316
OTO - NOTNLM
OT  - Acupoint-stimulation
OT  - Meta-analysis
OT  - Non-steroidal anti-inflammatory drugs
OT  - Primary dysmenorrhoea
OT  - Systematic review
EDAT- 2017/09/02 06:00
MHDA- 2017/09/09 06:00
CRDT- 2017/09/02 06:00
PHST- 2016/11/07 [received]
PHST- 2017/08/11 [accepted]
AID - 10.1186/s12906-017-1924-8 [doi]
AID - 10.1186/s12906-017-1924-8 [pii]
PST - epublish
SO  - BMC Complement Altern Med. 2017 Aug 31;17(1):436. doi: 10.1186/s12906-017-1924-8.