PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.




PMID- 28864371
OWN - NLM
STAT- In-Process
DA  - 20170902
LR  - 20170902
IS  - 1538-2990 (Electronic)
IS  - 0002-9629 (Linking)
VI  - 354
IP  - 2
DP  - 2017 Aug
TI  - Left Ventricular Noncompaction in Older Patients.
PG  - 140-144
LID - S0002-9629(17)30222-7 [pii]
LID - 10.1016/j.amjms.2017.04.012 [doi]
AB  - BACKGROUND: Information on left ventricular noncompaction (LVNC) in older people 
      is sparse. This study aimed to investigate the clinical profile of LVNC in an
      older cohort. MATERIALS AND METHODS: Between August 2007 and September 2015,
      older patients (age >/= 60 years) who were diagnosed with LVNC using
      cardiovascular magnetic resonance were prospectively enrolled at our hospital.
      RESULTS: A total of 35 patients (male, 80%; mean age, 65 +/- 5 years) were
      prospectively included in this study. LVNC was not detected in 18 patients (51%) 
      at the initial echocardiographic evaluation. Of the 21 patients who received
      coronary imaging, 8 patients (38%) had coronary artery disease. Left ventricular 
      (LV) dysfunction and dilation were detected in 31 patients (89%) and 30 patients 
      (86%), respectively. Nine patients (26%) died during a follow-up period of 2.9
      +/- 2.3 years. Cox analysis showed that patients with syncope (hazard ratio [HR] 
      = 20.51; 95% CI: 1.70-246.60; P = 0.02), increased LV end-diastolic diameter (HR 
      = 1.12; 95% CI: 1.01-1.24; P = 0.03), decreased LV ejection fraction (HR = 0.87; 
      95% CI: 0.77-0.98; P = 0.02) and the presence of late gadolinium enhancement on
      cardiovascular magnetic resonance (HR = 8.9; 95% CI: 1.07-74.08; P = 0.04) had a 
      higher risk for death. CONCLUSIONS: The diagnosis of LVNC is easily missed at
      echocardiographic assessment in older patients. Coronary artery disease is a
      common concomitant disorder in these patients. Older patients with LVNC have a
      high risk for mortality. Syncope, LV dilation, systolic dysfunction and late
      gadolinium enhancement are related to adverse outcomes in older patients.
CI  - Copyright (c) 2017 Southern Society for Clinical Investigation. Published by
      Elsevier Inc. All rights reserved.
FAU - Tian, Tao
AU  - Tian T
AD  - Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular
      Disease, Chinese Academy of Medical Sciences and Peking Union Medical College,
      Beijing, China.
FAU - Yang, Kun-Qi
AU  - Yang KQ
AD  - Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular
      Disease, Chinese Academy of Medical Sciences and Peking Union Medical College,
      Beijing, China.
FAU - Mao, Yi
AU  - Mao Y
AD  - Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular
      Disease, Chinese Academy of Medical Sciences and Peking Union Medical College,
      Beijing, China.
FAU - Zhou, Lan-Lan
AU  - Zhou LL
AD  - Department of Hematology and Oncology, The Second People's Hospital of Hefei,
      Hefei, China.
FAU - Wang, Lin-Ping
AU  - Wang LP
AD  - Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular
      Disease, Chinese Academy of Medical Sciences and Peking Union Medical College,
      Beijing, China.
FAU - Xiao, Yan
AU  - Xiao Y
AD  - Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular
      Disease, Chinese Academy of Medical Sciences and Peking Union Medical College,
      Beijing, China.
FAU - Yang, Yan-Kun
AU  - Yang YK
AD  - Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular
      Disease, Chinese Academy of Medical Sciences and Peking Union Medical College,
      Beijing, China.
FAU - Zhang, Yin
AU  - Zhang Y
AD  - Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular
      Disease, Chinese Academy of Medical Sciences and Peking Union Medical College,
      Beijing, China.
FAU - Meng, Xu
AU  - Meng X
AD  - Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular
      Disease, Chinese Academy of Medical Sciences and Peking Union Medical College,
      Beijing, China.
FAU - Zhou, Xian-Liang
AU  - Zhou XL
AD  - Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular
      Disease, Chinese Academy of Medical Sciences and Peking Union Medical College,
      Beijing, China. Electronic address: [email protected]
LA  - eng
PT  - Journal Article
DEP - 20170421
PL  - United States
TA  - Am J Med Sci
JT  - The American journal of the medical sciences
JID - 0370506
OTO - NOTNLM
OT  - Clinical presentation
OT  - Left ventricular noncompaction
OT  - Older patients
OT  - Prognosis
EDAT- 2017/09/03 06:00
MHDA- 2017/09/03 06:00
CRDT- 2017/09/03 06:00
PHST- 2016/12/11 [received]
PHST- 2017/02/09 [revised]
PHST- 2017/04/17 [accepted]
AID - S0002-9629(17)30222-7 [pii]
AID - 10.1016/j.amjms.2017.04.012 [doi]
PST - ppublish
SO  - Am J Med Sci. 2017 Aug;354(2):140-144. doi: 10.1016/j.amjms.2017.04.012. Epub
      2017 Apr 21.