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PMID- 29245266
DCOM- 20171225
LR  - 20171225
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 49
DP  - 2017 Dec
TI  - Gastric Burkitt lymphoma: A case report and literature review.
PG  - e8954
LID - 10.1097/MD.0000000000008954 [doi]
AB  - RATIONALE: Burkitt lymphoma (BL) is an endemic tumor in Africa but rare sporadic 
      cases are diagnosed in Europe. PATIENT CONCERNS: A 60-year-old woman was
      hospitalized with fulminant hematemesis and a history of recurring melena.
      DIAGNOSES: The upper gastrointestinal endoscopy revealed a tumor of the antrum.
      INTERVENTIONS: Emergency gastrectomy was performed. OUTCOMES: Gross findings
      revealed an ulcerated tumor with elevated margins and several perigastric and
      extragastric lymph nodes. Histological examination showed proliferation of
      atypical lymphocytes with a Ki67 index of 100%; they were marked by CD20, CD79a, 
      bcl-6, and CD10 and were negative for CD3, CD5, CD23, TdT, bcl-2, and Cyclin D1. 
      The tumor cells crossed the serosa and presented invasion of the lymph nodes. The
      patient died 10 days after surgery due to bronchopneumonia and acute renal
      failure. LESSONS: In our department, only one gastric BL was diagnosed in a 61
      consecutive lymphomas of the gastrointestinal tract (1.64%). Less than 200
      reports about gastric-BL have been published to date. This case highlights the
      difficulty of diagnosis of rare variants of aggressive gastric lymphomas in
      medium-income countries without screening programmes.
FAU - Gurzu, Simona
AU  - Gurzu S
AD  - aDepartment of PathologybDepartment of Pathology, Clinical County Emergency
      HospitalcDepartment of Surgery, University of Medicine and Pharmacy, Tirgu-Mures,
FAU - Bara, Tivadar
AU  - Bara T
FAU - Bara, Tivadar Jr
AU  - Bara TJ
FAU - Turcu, Mihai
AU  - Turcu M
FAU - Mardare, Ciprian Valentin
AU  - Mardare CV
FAU - Jung, Ioan
AU  - Jung I
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Biomarkers, Tumor)
SB  - IM
MH  - Biomarkers, Tumor/analysis
MH  - Burkitt Lymphoma/*diagnosis/pathology/*surgery
MH  - Emergencies
MH  - Fatal Outcome
MH  - Female
MH  - Gastrectomy
MH  - Gastroscopy
MH  - Humans
MH  - Lymphatic Metastasis
MH  - Middle Aged
MH  - Stomach Neoplasms/*diagnosis/pathology/*surgery
PMC - PMC5728881
EDAT- 2017/12/17 06:00
MHDA- 2017/12/26 06:00
CRDT- 2017/12/17 06:00
PHST- 2017/12/17 06:00 [entrez]
PHST- 2017/12/17 06:00 [pubmed]
PHST- 2017/12/26 06:00 [medline]
AID - 10.1097/MD.0000000000008954 [doi]
AID - 00005792-201712080-00055 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Dec;96(49):e8954. doi: 10.1097/MD.0000000000008954.