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PMID- 29245317
DCOM- 20180108
LR  - 20180108
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 49
DP  - 2017 Dec
TI  - Bone marrow necrosis secondary to metastatic adenocarcinoma revealed by 18F-FDG
      PET/CT: A clinical case report.
PG  - e9067
LID - 10.1097/MD.0000000000009067 [doi]
AB  - RATIONALE: Bone marrow necrosis (BMN) is a rare malignancy-associated hematologic
      disorder characterized by necrosis of myeloid and stromal marrow elements with
      preservation of cortical bone. PATIENT CONCERNS: A 43-year-old female complaining
      of dizziness and vaginal bleeding for more than 2 months was presented to our
      department. DIAGNOSIS: Due to the laboratory test results, radiographic findings,
      especially F-fluoro-2-deoxy-D-glucose (F-FDG) positron emission
      tomography/computed tomography (PET/CT) which revealed that bone marrow was
      characterized by diffuse F-FDG uptake with extensive central photopenia, and
      pathologic results, she was diagnosed with metastatic adenocarcinoma accompanied 
      with BMN. And the cancer most likely originated from reproductive system or
      breast. INTERVENTIONS: There was no effective interventions for her before
      knowing the accurate origin of adenocarcinoma. OUTCOMES: Two weeks later,
      unfortunately, she died. LESSONS: F-FDG PET/CT is a useful diagnostic modality in
      patients with BMN. Malignant tumor should always be considered in patients with
      extensive BMN, even in young people.
FAU - Dong, Ping
AU  - Dong P
AD  - Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu,
      P.R. China.
FAU - Tian, Rong
AU  - Tian R
FAU - Li, Lin
AU  - Li L
FAU - Su, Minggang
AU  - Su M
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Radiopharmaceuticals)
RN  - 0Z5B2CJX4D (Fluorodeoxyglucose F18)
SB  - IM
MH  - Adenocarcinoma/*diagnostic imaging/*pathology
MH  - Adult
MH  - Bone Marrow Neoplasms/*diagnostic imaging/*pathology
MH  - Fatal Outcome
MH  - Female
MH  - Fluorodeoxyglucose F18
MH  - Humans
MH  - Necrosis
MH  - Neoplasms, Unknown Primary/*diagnostic imaging/*pathology
MH  - *Positron Emission Tomography Computed Tomography
MH  - Radiopharmaceuticals
PMC - PMC5728932
EDAT- 2017/12/17 06:00
MHDA- 2018/01/09 06:00
CRDT- 2017/12/17 06:00
PHST- 2017/12/17 06:00 [entrez]
PHST- 2017/12/17 06:00 [pubmed]
PHST- 2018/01/09 06:00 [medline]
AID - 10.1097/MD.0000000000009067 [doi]
AID - 00005792-201712080-00106 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Dec;96(49):e9067. doi: 10.1097/MD.0000000000009067.