Bone marrow necrosis secondary to metastatic adenocarcinoma revealed by 18F-FDG PET/CT: A clinical case report.
|Abstract||Bone marrow necrosis (BMN) is a rare malignancy-associated hematologic disorder characterized by necrosis of myeloid and stromal marrow elements with preservation of cortical bone.|
Bone metastasis versus bone marrow metastasis? Integration of diagnosis by (18)F-fluorodeoxyglucose positron emission/computed tomography in advanced malignancy with super bone scan: two case reports and literature review.
|Publication Year Start||2018-01-01|
PMID- 29245317 OWN - NLM STAT- MEDLINE DCOM- 20180108 LR - 20180108 IS - 1536-5964 (Electronic) IS - 0025-7974 (Linking) VI - 96 IP - 49 DP - 2017 Dec TI - Bone marrow necrosis secondary to metastatic adenocarcinoma revealed by 18F-FDG PET/CT: A clinical case report. PG - e9067 LID - 10.1097/MD.0000000000009067 [doi] AB - RATIONALE: Bone marrow necrosis (BMN) is a rare malignancy-associated hematologic disorder characterized by necrosis of myeloid and stromal marrow elements with preservation of cortical bone. PATIENT CONCERNS: A 43-year-old female complaining of dizziness and vaginal bleeding for more than 2 months was presented to our department. DIAGNOSIS: Due to the laboratory test results, radiographic findings, especially F-fluoro-2-deoxy-D-glucose (F-FDG) positron emission tomography/computed tomography (PET/CT) which revealed that bone marrow was characterized by diffuse F-FDG uptake with extensive central photopenia, and pathologic results, she was diagnosed with metastatic adenocarcinoma accompanied with BMN. And the cancer most likely originated from reproductive system or breast. INTERVENTIONS: There was no effective interventions for her before knowing the accurate origin of adenocarcinoma. OUTCOMES: Two weeks later, unfortunately, she died. LESSONS: F-FDG PET/CT is a useful diagnostic modality in patients with BMN. Malignant tumor should always be considered in patients with extensive BMN, even in young people. FAU - Dong, Ping AU - Dong P AD - Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, P.R. China. FAU - Tian, Rong AU - Tian R FAU - Li, Lin AU - Li L FAU - Su, Minggang AU - Su M LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Medicine (Baltimore) JT - Medicine JID - 2985248R RN - 0 (Radiopharmaceuticals) RN - 0Z5B2CJX4D (Fluorodeoxyglucose F18) SB - AIM SB - IM MH - Adenocarcinoma/*diagnostic imaging/*pathology MH - Adult MH - Bone Marrow Neoplasms/*diagnostic imaging/*pathology MH - Fatal Outcome MH - Female MH - Fluorodeoxyglucose F18 MH - Humans MH - Necrosis MH - Neoplasms, Unknown Primary/*diagnostic imaging/*pathology MH - *Positron Emission Tomography Computed Tomography MH - Radiopharmaceuticals PMC - PMC5728932 EDAT- 2017/12/17 06:00 MHDA- 2018/01/09 06:00 CRDT- 2017/12/17 06:00 PHST- 2017/12/17 06:00 [entrez] PHST- 2017/12/17 06:00 [pubmed] PHST- 2018/01/09 06:00 [medline] AID - 10.1097/MD.0000000000009067 [doi] AID - 00005792-201712080-00106 [pii] PST - ppublish SO - Medicine (Baltimore). 2017 Dec;96(49):e9067. doi: 10.1097/MD.0000000000009067.