PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.




PMID- 29246122
OWN - NLM
STAT- MEDLINE
DCOM- 20180105
LR  - 20180105
IS  - 1471-2415 (Electronic)
IS  - 1471-2415 (Linking)
VI  - 17
IP  - 1
DP  - 2017 Dec 16
TI  - Structural changes of the macula and optic nerve head in the remaining eyes after
      enucleation for retinoblastoma: an optical coherence tomography study.
PG  - 251
LID - 10.1186/s12886-017-0650-9 [doi]
AB  - BACKGROUND: To describe objectively the possible structural changes of the macula
      and optic nerve head in the free eyes of unilateral cured retinoblastoma patients
      and, also after enucleation using spectral domain optical coherence tomography.
      METHODS: A cross sectional study involving 60 patients subdivided into three
      groups; 15 unilateral RB patients in whom enucleation was indicated as a sole
      treatment performed earlier in life [(study group (I)], 15 unilateral RB patients
      who had completely regressed disease with a preserved eye [(study group (II)] and
      30 age and sex matched healthy controls. The remaining and free eyes in study
      groups and right eyes of control group had full ophthalmological examination,
      static automated perimetry and optical coherence tomography of the macula and
      optic nerve head. RESULTS: In study group (II); a significant thinning of total
      macula, central fovea, ganglion cell layer (GCL), ganglion cell complex (GCC),
      and some sectors of outer nuclear layer (P- values </=0.05) was found with no
      significant difference in peripapillary nerve fiber layer (pRNFL) thickness and
      optic nerve head parameters compared to the control group and the study group
      (I). A significantly thickened total macula, GCL, GCC, and pRNFL in study group
      (I) compared to study group (II). Thickened pRNFL was significantly correlated to
      standard automated perimetry pattern deviations. No significant difference was
      found between study group (I) and control group. CONCLUSION: Retinoblastoma eyes 
      characterized by thinning of central fovea, GCL, GCC compared to the control
      group. After unilateral enucleation, increased GCC and pRNFL thicknesses were
      detected compared to retinoblastoma group.
FAU - Said, Azza Mohamed Ahmed
AU  - Said AMA
AD  - Ophthalmology Department, Faculty of Medicine, Ain Shams University,
      Corresponding author address: 10 th Fawzy Elmoteay street, Heliopolis, Cairo,
      Postal code: 11736, Egypt. [email protected]
FAU - Elbayomi, Ahmed Mohamed
AU  - Elbayomi AM
AD  - Ophthalmology Department, Faculty of Medicine, Ain Shams University,
      Corresponding author address: 10 th Fawzy Elmoteay street, Heliopolis, Cairo,
      Postal code: 11736, Egypt.
FAU - Shaat, Ashraf Abdelsalam Kandeel
AU  - Shaat AAK
AD  - Ophthalmology Department, Faculty of Medicine, Ain Shams University,
      Corresponding author address: 10 th Fawzy Elmoteay street, Heliopolis, Cairo,
      Postal code: 11736, Egypt.
LA  - eng
PT  - Journal Article
DEP - 20171216
PL  - England
TA  - BMC Ophthalmol
JT  - BMC ophthalmology
JID - 100967802
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Case-Control Studies
MH  - Child
MH  - Child, Preschool
MH  - Cross-Sectional Studies
MH  - *Eye Enucleation
MH  - Female
MH  - Humans
MH  - Macula Lutea/*pathology
MH  - Male
MH  - Nerve Fibers/pathology
MH  - Optic Disk/*pathology
MH  - Retinal Ganglion Cells/pathology
MH  - Retinal Neoplasms/*pathology/surgery
MH  - Retinoblastoma/*pathology/surgery
MH  - Tomography, Optical Coherence/methods
MH  - Young Adult
PMC - PMC5732405
OTO - NOTNLM
OT  - Enucleation
OT  - Ganglion cell complex
OT  - Peripapillary nerve fiber layer
OT  - Retinoblastoma
EDAT- 2017/12/17 06:00
MHDA- 2018/01/06 06:00
CRDT- 2017/12/17 06:00
PHST- 2017/08/25 00:00 [received]
PHST- 2017/12/05 00:00 [accepted]
PHST- 2017/12/17 06:00 [entrez]
PHST- 2017/12/17 06:00 [pubmed]
PHST- 2018/01/06 06:00 [medline]
AID - 10.1186/s12886-017-0650-9 [doi]
AID - 10.1186/s12886-017-0650-9 [pii]
PST - epublish
SO  - BMC Ophthalmol. 2017 Dec 16;17(1):251. doi: 10.1186/s12886-017-0650-9.