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PMID- 29255549
OWN - NLM
STAT- MEDLINE
DCOM- 20171222
LR  - 20171222
IS  - 1937-8688 (Electronic)
VI  - 28
DP  - 2017
TI  - Left ventricular hypertrophy among chronic kidney disease patients in Ghana.
PG  - 79
LID - 10.11604/pamj.2017.28.79.9183 [doi]
AB  - Introduction: The presence of left ventricular hypertrophy (LVH) in patients with
      Chronic Kidney Disease (CKD) is associated with worsening cardiovascular
      outcomes. There is a dearth of data on LVH in Ghanaian CKD patients. Methods:
      This was a cross sectional study carried out at the Komfo Anokye Teaching
      Hospital (KATH) in Kumasi, Ghana. A questionnaire was used to obtain information 
      on clinical features of CKD. The MDRD-4 equation was used to calculate eGFR.
      Information on the prevalence and factors associated with electrocardiographic
      left ventricular hypertrophy were obtained during the initial assessment.
      Results: About 64.5% of the 203 participants were male and the mean age was 43.9 
      +/- 17.8 years. Most subjects (79.8%) had stage 5 disease. The mean systolic and 
      diastolic blood pressures were 167.86 +/- 39.87 and 101.8 +/- 24.4 respectively. 
      Approximately 43% of respondents had LVH. eGFR correlated negatively with LVH.
      High systolic pressure (OR 4.9, CI 2.4 - 10.4; p < 0.05), high diastolic pressure
      (OR 8.1, CI 4.0 - 16.1; p < 0.05) increased pulse pressure (OR 3.4 CI 2.6-9.3, p 
      < 0.05), increased body mass index (OR 3.6 CI 1.7-11.2, p < 0.001) as well as
      male gender (OR 4.7, 95% CI 2.4 - 9.1; p <0.05) were associated with the presence
      of LVH. Conclusion: LVH is common in our cohort. High pulse pressure, high DBP,
      increased BMI and male gender are significant associated factors. Adequate
      treatment of high blood pressure as well as early detection of LVH and
      interventions aimed at prevention and/or regression of LVH are to be encouraged.
FAU - Amoako, Yaw Ampem
AU  - Amoako YA
AD  - Renal Medicine and Dialysis Unit, Department of Medicine, Komfo Anokye Teaching
      Hospital, Kumasi, Ghana.
FAU - Laryea, Dennis Odai
AU  - Laryea DO
AD  - Disease Control Department, Ghana Health Service, Accra, Ghana.
FAU - Bedu-Addo, George
AU  - Bedu-Addo G
AD  - Renal Medicine and Dialysis Unit, Department of Medicine, Komfo Anokye Teaching
      Hospital, Kumasi, Ghana.
AD  - School of Medical Sciences, Kwame Nkrumah University of Science and Technology,
      Kumasi, Ghana.
FAU - Nkum, Bernard Cudjoe
AU  - Nkum BC
AD  - Renal Medicine and Dialysis Unit, Department of Medicine, Komfo Anokye Teaching
      Hospital, Kumasi, Ghana.
AD  - School of Medical Sciences, Kwame Nkrumah University of Science and Technology,
      Kumasi, Ghana.
FAU - Plange-Rhule, Jacob
AU  - Plange-Rhule J
AD  - Renal Medicine and Dialysis Unit, Department of Medicine, Komfo Anokye Teaching
      Hospital, Kumasi, Ghana.
AD  - School of Medical Sciences, Kwame Nkrumah University of Science and Technology,
      Kumasi, Ghana.
LA  - eng
PT  - Journal Article
DEP - 20170927
PL  - Uganda
TA  - Pan Afr Med J
JT  - The Pan African medical journal
JID - 101517926
SB  - IM
MH  - Adult
MH  - *Blood Pressure
MH  - Body Mass Index
MH  - Cross-Sectional Studies
MH  - Electrocardiography
MH  - Female
MH  - Ghana
MH  - Glomerular Filtration Rate
MH  - Hospitals, Teaching
MH  - Humans
MH  - Hypertension/*epidemiology
MH  - Hypertrophy, Left Ventricular/*epidemiology
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Renal Insufficiency, Chronic/*complications
MH  - Risk Factors
MH  - Sex Factors
MH  - Surveys and Questionnaires
PMC - PMC5724957
OTO - NOTNLM
OT  - Ghana
OT  - Left ventricular hypertrophy
OT  - chronic kidney disease
OT  - prevalence
OT  - sokolow-lyon criteria
EDAT- 2017/12/20 06:00
MHDA- 2017/12/23 06:00
CRDT- 2017/12/20 06:00
PHST- 2016/02/24 00:00 [received]
PHST- 2017/09/13 00:00 [accepted]
PHST- 2017/12/20 06:00 [entrez]
PHST- 2017/12/20 06:00 [pubmed]
PHST- 2017/12/23 06:00 [medline]
AID - 10.11604/pamj.2017.28.79.9183 [doi]
AID - PAMJ-28-79 [pii]
PST - epublish
SO  - Pan Afr Med J. 2017 Sep 27;28:79. doi: 10.11604/pamj.2017.28.79.9183. eCollection
      2017.