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Perineal verrucous lesions.

Abstract Verrucous lichen planus (VLP), is a chronic inflammatory dermatosis mainly involving the lower limbs. It rarely affects the perineal area, where it occurs in association with other mucocutaneous lichen lesions. We here report the case of a 51-year old patient with isolated perineal verrucous lichen planus. The patient, who had no significant medical history, presented with painless, verrucous, slightly itchy lesions in the perineal area that had gradually increased in volume over the past 8 years. Clinical examination revealed the presence of multiple firm grayish budding lesions with a rough surface, measuring 1-4 cm in diameter, in the perianal and scrotal area (A). The remainder of the somatic examination was normal. Histology showed verrucous acanthotic epidermis associated with mainly lymphocytic inflammatory infiltrate penetrating the basement membrane and pigmentary incontinence with the formation of apoptotic bodies in the basal layer of epidermis, without signs of viral infection or malignant transformation (B). The diagnosis of verrucous lichen planus was retained. Hepatitis C serology, lipid assessment as well as abdominal ultrasound were normal. A very strong local corticosteroid therapy was prescribed. The patient had a favorable outcome without recidivism at 18-months' follow-up.
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Authors

Mayor MeshTerms
Keywords

Lichen planus

hypertrophic

perineal

verrucous

Journal Title the pan african medical journal
Publication Year Start




PMID- 29255568
OWN - NLM
STAT- MEDLINE
DCOM- 20171222
LR  - 20171222
IS  - 1937-8688 (Electronic)
VI  - 28
DP  - 2017
TI  - [Perineal verrucous lesions].
PG  - 98
LID - 10.11604/pamj.2017.28.98.13844 [doi]
AB  - Verrucous lichen planus (VLP), is a chronic inflammatory dermatosis mainly
      involving the lower limbs. It rarely affects the perineal area, where it occurs
      in association with other mucocutaneous lichen lesions. We here report the case
      of a 51-year old patient with isolated perineal verrucous lichen planus. The
      patient, who had no significant medical history, presented with painless,
      verrucous, slightly itchy lesions in the perineal area that had gradually
      increased in volume over the past 8 years. Clinical examination revealed the
      presence of multiple firm grayish budding lesions with a rough surface, measuring
      1-4 cm in diameter, in the perianal and scrotal area (A). The remainder of the
      somatic examination was normal. Histology showed verrucous acanthotic epidermis
      associated with mainly lymphocytic inflammatory infiltrate penetrating the
      basement membrane and pigmentary incontinence with the formation of apoptotic
      bodies in the basal layer of epidermis, without signs of viral infection or
      malignant transformation (B). The diagnosis of verrucous lichen planus was
      retained. Hepatitis C serology, lipid assessment as well as abdominal ultrasound 
      were normal. A very strong local corticosteroid therapy was prescribed. The
      patient had a favorable outcome without recidivism at 18-months' follow-up.
FAU - Naciri, Ilhame
AU  - Naciri I
AD  - Service de Dermatologie et Venerologie, Centre Hospitalier Universitaire Ibn
      Sina, Faculte de Medecine et de Pharmacie, Universite Mohammed V, Rabat, Maroc.
FAU - Hassam, Baderddine
AU  - Hassam B
AD  - Service de Dermatologie et Venerologie, Centre Hospitalier Universitaire Ibn
      Sina, Faculte de Medecine et de Pharmacie, Universite Mohammed V, Rabat, Maroc.
LA  - fre
PT  - Case Reports
PT  - Journal Article
TT  - Lesions verruqueuses perineales.
DEP - 20170929
PL  - Uganda
TA  - Pan Afr Med J
JT  - The Pan African medical journal
JID - 101517926
RN  - 0 (Adrenal Cortex Hormones)
SB  - IM
MH  - Adrenal Cortex Hormones/therapeutic use
MH  - Follow-Up Studies
MH  - Humans
MH  - Lichen Planus/*diagnosis/drug therapy/pathology
MH  - Male
MH  - Middle Aged
MH  - Perineum/*pathology
MH  - Scrotum/*pathology
PMC - PMC5724936
OTO - NOTNLM
OT  - Lichen planus
OT  - hypertrophic
OT  - perineal
OT  - verrucous
EDAT- 2017/12/20 06:00
MHDA- 2017/12/23 06:00
CRDT- 2017/12/20 06:00
PHST- 2017/09/10 00:00 [received]
PHST- 2017/09/23 00:00 [accepted]
PHST- 2017/12/20 06:00 [entrez]
PHST- 2017/12/20 06:00 [pubmed]
PHST- 2017/12/23 06:00 [medline]
AID - 10.11604/pamj.2017.28.98.13844 [doi]
AID - PAMJ-28-98 [pii]
PST - epublish
SO  - Pan Afr Med J. 2017 Sep 29;28:98. doi: 10.11604/pamj.2017.28.98.13844.
      eCollection 2017.