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Diabetic Retinopathy and Macular Edema Quality-of-Life Item Banks: Development and Initial Evaluation Using Computerized Adaptive Testing.

Abstract The purpose of this study was to assess the psychometric properties of diabetic retinopathy (DR) and diabetic macular edema (DME) quality-of-life (QoL) item banks and determine the utility of the final calibrated item banks by simulating a computerized adaptive testing (CAT) application.
PMID
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Authors

Mayor MeshTerms

Quality of Life

Surveys and Questionnaires

Keywords
Journal Title investigative ophthalmology & visual science
Publication Year Start




PMID- 29260195
OWN - NLM
STAT- MEDLINE
DCOM- 20171227
LR  - 20171227
IS  - 1552-5783 (Electronic)
IS  - 0146-0404 (Linking)
VI  - 58
IP  - 14
DP  - 2017 Dec 1
TI  - Diabetic Retinopathy and Macular Edema Quality-of-Life Item Banks: Development
      and Initial Evaluation Using Computerized Adaptive Testing.
PG  - 6379-6387
LID - 10.1167/iovs.16-20950 [doi]
AB  - Purpose: The purpose of this study was to assess the psychometric properties of
      diabetic retinopathy (DR) and diabetic macular edema (DME) quality-of-life (QoL) 
      item banks and determine the utility of the final calibrated item banks by
      simulating a computerized adaptive testing (CAT) application. Methods: In this
      clinical, cross-sectional study, 514 participants with DR/DME (mean age +/- SD,
      60.4 +/- 12.6 years; 64% male) answered 314 items grouped under nine QoL item
      pools: Visual Symptoms (SY); Ocular Comfort Symptoms (OS); Activity Limitation
      (AL); Mobility (MB); Emotional (EM); Health Concerns (HC); Social (SC);
      Convenience (CV); and Economic (EC). The psychometric properties of the item
      pools were assessed using Rasch analysis, and CAT simulations determined the
      average number of items administered at high and moderate precision levels.
      Results: The SY, MB, EM, and HC item pools required minor amendments, mainly
      involving removal of six poorly worded, highly misfitting items. AL and CV
      required substantial modification to resolve multidimensionality, which resulted 
      in two new item banks: Driving (DV) and Lighting (LT). Due to unresolvable
      psychometric issues, the OS, SC, and EC item pools were not pursued further. This
      iterative process resulted in eight operational item banks that underwent CAT
      simulations. Correlations between CAT and the full item banks were high (range,
      0.88-0.99). On average, only 3.6 and 7.2 items were required to gain measurement 
      at moderate and high precision, respectively. Conclusions: Our eight
      psychometrically robust and efficient DR/DME item banks will enable researchers
      and clinicians to accurately assess the impact and effectiveness of treatment
      therapies for DR/DME in all areas of QoL.
FAU - Fenwick, Eva K
AU  - Fenwick EK
AD  - Centre for Eye Research Australia, The Royal Victorian Eye and Ear Hospital,
      University of Melbourne, Melbourne, Australia.
AD  - Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
AD  - Duke-NUS, Singapore, National University of Singapore, Singapore.
FAU - Khadka, Jyoti
AU  - Khadka J
AD  - Discipline of Optometry and Vision Science, Flinders University of South
      Australia, South Australia, Australia.
FAU - Pesudovs, Konrad
AU  - Pesudovs K
AD  - Discipline of Optometry and Vision Science, Flinders University of South
      Australia, South Australia, Australia.
FAU - Rees, Gwyn
AU  - Rees G
AD  - Centre for Eye Research Australia, The Royal Victorian Eye and Ear Hospital,
      University of Melbourne, Melbourne, Australia.
FAU - Wong, Tien Y
AU  - Wong TY
AD  - Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
AD  - Duke-NUS, Singapore, National University of Singapore, Singapore.
FAU - Lamoureux, Ecosse L
AU  - Lamoureux EL
AD  - Centre for Eye Research Australia, The Royal Victorian Eye and Ear Hospital,
      University of Melbourne, Melbourne, Australia.
AD  - Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
AD  - Duke-NUS, Singapore, National University of Singapore, Singapore.
LA  - eng
PT  - Clinical Study
PT  - Journal Article
PL  - United States
TA  - Invest Ophthalmol Vis Sci
JT  - Investigative ophthalmology & visual science
JID - 7703701
SB  - IM
MH  - Aged
MH  - Cross-Sectional Studies
MH  - Diabetic Retinopathy/*psychology
MH  - Female
MH  - Humans
MH  - Macular Edema/*psychology
MH  - Male
MH  - Middle Aged
MH  - Psychometrics/*methods
MH  - *Quality of Life
MH  - *Surveys and Questionnaires
EDAT- 2017/12/21 06:00
MHDA- 2017/12/28 06:00
CRDT- 2017/12/21 06:00
PHST- 2017/12/21 06:00 [entrez]
PHST- 2017/12/21 06:00 [pubmed]
PHST- 2017/12/28 06:00 [medline]
AID - 2667134 [pii]
AID - 10.1167/iovs.16-20950 [doi]
PST - ppublish
SO  - Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6379-6387. doi:
      10.1167/iovs.16-20950.