PubTransformer

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PMID- 29260196
OWN - NLM
STAT- MEDLINE
DCOM- 20171227
LR  - 20171227
IS  - 1552-5783 (Electronic)
IS  - 0146-0404 (Linking)
VI  - 58
IP  - 14
DP  - 2017 Dec 1
TI  - Development and Validation of a Risk Score for Age-Related Macular Degeneration: 
      The STARS Questionnaire.
PG  - 6399-6407
LID - 10.1167/iovs.17-21819 [doi]
AB  - Purpose: To develop and validate a risk score for AMD based on a simple
      self-administered questionnaire. Methods: Risk factors having shown the most
      consistent associations with AMD were included in the STARS (Simplified Thea AMD 
      Risk-Assessment Scale) questionnaire. Two studies were conducted, one in Italy
      (127 participating ophthalmologists) and one in France (80 participating
      ophthalmologists). During 1 week, participating ophthalmologists invited all
      their patients aged 55 years or older to fill in the STARS questionnaire. Based
      on fundus examination, early AMD was defined by the presence of soft drusen
      and/or pigmentary abnormalities and late AMD by the presence of geographic
      atrophy and/or neovascular AMD. Results: The Italian and French samples consisted
      of 12,639 and 6897 patients, respectively. All 13 risk factors included in the
      STARS questionnaire showed significant associations with AMD in the Italian
      sample. The area under the receiving operating characteristic curve for the STARS
      risk score, derived from the multivariate logistic regression in the Italian
      sample, was 0.78 in the Italian sample and 0.72 in the French sample. In both
      samples, less than 10% of patients without AMD were classified at high risk, and 
      less than 13% of late AMD cases were classified as low risk, with a more
      intermediate situation in early AMD cases. Conclusions: STARS is a new, simple
      self-assessed questionnaire showing good discrimination of risk for AMD in two
      large European samples. It might be used by ophthalmologists in routine clinical 
      practice or as a self-assessment for risk of AMD in the general population.
FAU - Delcourt, Cecile
AU  - Delcourt C
AD  - University of Bordeaux, Inserm, Bordeaux Population Health Research Center, Team 
      LEHA, UMR 1219, Bordeaux, France.
FAU - Souied, Eric
AU  - Souied E
AD  - University Paris-Est, Hopital Inter-Communal de Creteil, Creteil, France.
FAU - Sanchez, Alice
AU  - Sanchez A
AD  - Biostatem, Castries, France.
FAU - Bandello, Francesco
AU  - Bandello F
AD  - Department of Ophthalmology, University Vita-Salute, Scientific Institute San
      Raffaele, Milan, Italy.
CN  - STARS Survey Group
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Validation Studies
PL  - United States
TA  - Invest Ophthalmol Vis Sci
JT  - Investigative ophthalmology & visual science
JID - 7703701
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Algorithms
MH  - Female
MH  - Humans
MH  - Logistic Models
MH  - Macular Degeneration/*diagnosis
MH  - Male
MH  - Middle Aged
MH  - Risk Assessment/methods
MH  - Risk Factors
MH  - Sensitivity and Specificity
MH  - Surveys and Questionnaires/*standards
EDAT- 2017/12/21 06:00
MHDA- 2017/12/28 06:00
CRDT- 2017/12/21 06:00
PHST- 2017/12/21 06:00 [entrez]
PHST- 2017/12/21 06:00 [pubmed]
PHST- 2017/12/28 06:00 [medline]
AID - 2667135 [pii]
AID - 10.1167/iovs.17-21819 [doi]
PST - ppublish
SO  - Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6399-6407. doi:
      10.1167/iovs.17-21819.