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Debulking Surgery for Pelvic Recurrence After Surgically-treated Tubal Gestational Choriocarcinoma - A Case Report and Literature Review.

Abstract Gestational choriocarcinomas are very rare malignancies, with only few cases being reported so far. Moreover, the presence of pelvic recurrences after surgically-treated gestational choriocarcinomas is even scarcer situations. We present the case of a 19-year-old patient who was initially submitted to surgery with preoperative diagnosis of ectopic pregnancy. At that moment a left salpingectomy was performed, and the histopathological studies revealed the presence of a left tubal gestational choriocarcinoma. The patient was submitted to adjuvant chemotherapy with methotrexate and dactinomycin. However, six months later she was diagnosed with a pelvic recurrence so she was resubmitted to surgery, debulking to no residual disease being successfully performed. The histopathological studies confirmed the presence of a recurrent tumor with gestational choriocarcinoma structure.
PMID
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Authors

Mayor MeshTerms
Keywords

Ectopic pregnancy

debulking surgery

gestational choriocarcinoma

Journal Title anticancer research
Publication Year Start




PMID- 29277804
OWN - NLM
STAT- In-Process
LR  - 20171226
IS  - 1791-7530 (Electronic)
IS  - 0250-7005 (Linking)
VI  - 38
IP  - 1
DP  - 2018 Jan
TI  - Debulking Surgery for Pelvic Recurrence After Surgically-treated Tubal
      Gestational Choriocarcinoma - A Case Report and Literature Review.
PG  - 423-426
AB  - Gestational choriocarcinomas are very rare malignancies, with only few cases
      being reported so far. Moreover, the presence of pelvic recurrences after
      surgically-treated gestational choriocarcinomas is even scarcer situations. We
      present the case of a 19-year-old patient who was initially submitted to surgery 
      with preoperative diagnosis of ectopic pregnancy. At that moment a left
      salpingectomy was performed, and the histopathological studies revealed the
      presence of a left tubal gestational choriocarcinoma. The patient was submitted
      to adjuvant chemotherapy with methotrexate and dactinomycin. However, six months 
      later she was diagnosed with a pelvic recurrence so she was resubmitted to
      surgery, debulking to no residual disease being successfully performed. The
      histopathological studies confirmed the presence of a recurrent tumor with
      gestational choriocarcinoma structure.
CI  - Copyright(c) 2018, International Institute of Anticancer Research (Dr. George J. 
      Delinasios), All rights reserved.
FAU - Bacalbasa, Nicolae
AU  - Bacalbasa N
AD  - "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
FAU - Balescu, Irina
AU  - Balescu I
AD  - "Ponderas Academic Hospital", Bucharest, Romania [email protected]
FAU - Brasoveanu, Vladislav
AU  - Brasoveanu V
AD  - "Dan Setlacec" Center of General Surgery and Liver Transplantation, Fundeni
      Clnical Institute, Bucharest, Romania.
FAU - Anca, Alexandru Florin
AU  - Anca AF
AD  - "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
AD  - University Emergency Hospital, Bucharest, Romania.
LA  - eng
PT  - Journal Article
PL  - Greece
TA  - Anticancer Res
JT  - Anticancer research
JID - 8102988
OTO - NOTNLM
OT  - Ectopic pregnancy
OT  - debulking surgery
OT  - gestational choriocarcinoma
EDAT- 2017/12/27 06:00
MHDA- 2017/12/27 06:00
CRDT- 2017/12/27 06:00
PHST- 2017/10/05 00:00 [received]
PHST- 2017/11/05 00:00 [revised]
PHST- 2017/11/05 00:00 [accepted]
PHST- 2017/12/27 06:00 [entrez]
PHST- 2017/12/27 06:00 [pubmed]
PHST- 2017/12/27 06:00 [medline]
AID - 38/1/423 [pii]
PST - ppublish
SO  - Anticancer Res. 2018 Jan;38(1):423-426.