PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.




PMID- 29277826
OWN - NLM
STAT- In-Process
LR  - 20171226
IS  - 1791-7530 (Electronic)
IS  - 0250-7005 (Linking)
VI  - 38
IP  - 1
DP  - 2018 Jan
TI  - Prognostic Significance of Mitochondrial Transcription Factor A Expression in
      Patients with Right- or Left-sided Colorectal Cancer.
PG  - 569-575
AB  - BACKGROUND/AIM: Mitochondrial transcription factor A (mtTFA) is necessary for
      both the transcription and maintenance of mitochondrial DNA (mtDNA). The present 
      study investigated the clinical significance of mtTFA in patients with right- and
      left-sided colorectal cancer (CRC). PATIENTS AND METHODS: Surgical specimens from
      237 CRC patients were immunohistochemically stained with polyclonal anti-mtTFA
      antibody. The relationships among the mtTFA expression, clinicopathological
      factors and prognosis were evaluated. RESULTS: Thirty-five (60.3%) of 58
      right-sided CRC patients and 82 (45.8%) of 179 left-sided CRC patients showed
      high mtTFA expression. The mtTFA expression significantly correlated with lymph
      node metastasis, distant metastasis, the TNM stage and lymphatic invasion in
      left-sided CRC patients and did not correlate with any factors in right-sided CRC
      patients. Univariate and multivariate analyses revealed the mtTFA expression to
      be a significant prognostic factor in left-sided CRC patients but not in
      right-sided CRC patients. CONCLUSION: These results suggest that a high mtTFA
      expression is a useful marker for tumor progression and a poor prognosis in
      left-sided CRC patients.
CI  - Copyright(c) 2018, International Institute of Anticancer Research (Dr. George J. 
      Delinasios), All rights reserved.
FAU - Katsuki, Takefumi
AU  - Katsuki T
AD  - Department of Surgery 1, School of Medicine, University of Occupational and
      Environmental Health, Kitakyushu, Japan.
FAU - Nakayama, Yoshifumi
AU  - Nakayama Y
AD  - Department of Surgery 1, School of Medicine, University of Occupational and
      Environmental Health, Kitakyushu, Japan [email protected]
AD  - Department of Gastroenterological and General Surgery, Wakamatsu Hospital of
      University of Occupational and Environmental Health, Kitakyushu, Japan.
FAU - Akiyama, Masaki
AU  - Akiyama M
AD  - Department of Surgery 1, School of Medicine, University of Occupational and
      Environmental Health, Kitakyushu, Japan.
AD  - Department of Gastroenterological and General Surgery, Wakamatsu Hospital of
      University of Occupational and Environmental Health, Kitakyushu, Japan.
FAU - Sawatsubashi, Yusuke
AU  - Sawatsubashi Y
AD  - Department of Surgery 1, School of Medicine, University of Occupational and
      Environmental Health, Kitakyushu, Japan.
AD  - Department of Gastroenterological and General Surgery, Wakamatsu Hospital of
      University of Occupational and Environmental Health, Kitakyushu, Japan.
FAU - Nagata, Jun
AU  - Nagata J
AD  - Department of Surgery 1, School of Medicine, University of Occupational and
      Environmental Health, Kitakyushu, Japan.
AD  - Department of Gastroenterological and General Surgery, Wakamatsu Hospital of
      University of Occupational and Environmental Health, Kitakyushu, Japan.
FAU - Minagawa, Noritaka
AU  - Minagawa N
AD  - Department of Surgery 1, School of Medicine, University of Occupational and
      Environmental Health, Kitakyushu, Japan.
FAU - Torigoe, Takayuki
AU  - Torigoe T
AD  - Department of Surgery 1, School of Medicine, University of Occupational and
      Environmental Health, Kitakyushu, Japan.
FAU - Izumi, Hiroto
AU  - Izumi H
AD  - Department of Occupational Pneumology, Institute of Industrial Ecological
      Science, University of Occupational and Environmental Health, Kitakyushu, Japan.
FAU - Kohono, Kimitoshi
AU  - Kohono K
AD  - Asahi Matsumoto Hospital, Kitakyushu, Japan.
FAU - Hirata, Keiji
AU  - Hirata K
AD  - Department of Surgery 1, School of Medicine, University of Occupational and
      Environmental Health, Kitakyushu, Japan.
LA  - eng
PT  - Journal Article
PL  - Greece
TA  - Anticancer Res
JT  - Anticancer research
JID - 8102988
OTO - NOTNLM
OT  - Mitochondrial transcription factor A
OT  - colorectal cancer
OT  - mitochondrial DNA
EDAT- 2017/12/27 06:00
MHDA- 2017/12/27 06:00
CRDT- 2017/12/27 06:00
PHST- 2017/09/29 00:00 [received]
PHST- 2017/10/17 00:00 [revised]
PHST- 2017/10/18 00:00 [accepted]
PHST- 2017/12/27 06:00 [entrez]
PHST- 2017/12/27 06:00 [pubmed]
PHST- 2017/12/27 06:00 [medline]
AID - 38/1/569 [pii]
PST - ppublish
SO  - Anticancer Res. 2018 Jan;38(1):569-575.