PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Chromium in urothelial carcinoma of the bladder.

Abstract Many epidemiological and experimental studies report a strong role of chemical carcinogens in the etiology of bladder cancer. However, the involvement of heavy metals in tumourigenesis of urothelial carcinoma of the bladder has been poorly investigated. Therefore, the aim of this study was to examine the relationship between chromium (Cr) and bladder cancer.
PMID
Related Publications

Expression of androgen and oestrogen receptors and its prognostic significance in urothelial neoplasm of the urinary bladder.

Lead concentration in the bladder tissue and blood of patients with bladder cancer.

Quantitative Evaluation of Heavy Metals and Trace Elements in the Urinary Bladder: Comparison Between Cancerous, Adjacent Non-cancerous and Normal Cadaveric Tissue.

Copper, zinc, and Cu/Zn ratio in transitional cell carcinoma of the bladder.

Cadmium in urothelial carcinoma of the bladder.

Authors

Mayor MeshTerms
Keywords

bladder cancer

chromium

heavy metals

Journal Title annals of agricultural and environmental medicine : aaem
Publication Year Start




PMID- 29284232
OWN - NLM
STAT- MEDLINE
DCOM- 20180105
LR  - 20180105
IS  - 1898-2263 (Electronic)
IS  - 1232-1966 (Linking)
VI  - 24
IP  - 4
DP  - 2017 Dec 23
TI  - Chromium in urothelial carcinoma of the bladder.
PG  - 602-605
LID - 72576 [pii]
LID - 10.5604/12321966.1232760 [doi]
AB  - INTRODUCTION AND OBJECTIVES: Many epidemiological and experimental studies report
      a strong role of chemical carcinogens in the etiology of bladder cancer. However,
      the involvement of heavy metals in tumourigenesis of urothelial carcinoma of the 
      bladder has been poorly investigated. Therefore, the aim of this study was to
      examine the relationship between chromium (Cr) and bladder cancer. MATERIAL AND
      METHODS: Chromium concentration in two 36-sample series of bladder cancer tissue 
      and sera from patients with this neoplasm were matched with those of a control
      group. The amount of trace elements in every tissue sample was determined using
      atomic absorption spectrometry. This was correlated with tumour stage. RESULTS:
      While the median chromium concentration levels reached statistically higher
      values in the bladder cancer tissue, compared with the non-cancer tissue
      (99.632ng/g and 33.144ng/g, respectively; p<0.001), the median Cr levels in the
      sera of the patients with this carcinoma showed no statistical difference when
      compared to those of the control group (0.511mug/l and 0.710mug/l, respectively; 
      p=0.408). The median levels of Cr in the bladder tissue, depending on the stage
      of the tumour, compared with the tissue without the neoplasm, observed the same
      relationship for both non-muscle invasive and muscle-invasive tumours (p<0.001
      and p<0.01, respectively). CONCLUSIONS: This study shows that patients with
      urothelial carcinoma of the bladder had higher tissue Cr levels than people
      without tumour, while no difference was found in the Cr serum levels between the 
      two groups of patients under investigation.
FAU - Golabek, Tomasz
AU  - Golabek T
AD  - Department of Urology, Medical College, Jagiellonian University, Krakow, Poland. 
      [email protected]
FAU - Socha, Katarzyna
AU  - Socha K
AD  - Department of Bromatology, Medical University, Bialystok, Poland.
FAU - Kudelski, Jacek
AU  - Kudelski J
AD  - Department of Urology, Medical University, Bialystok, Poland.
FAU - Darewicz, Barbara
AU  - Darewicz B
AD  - Department of Urology, Medical University, Bialystok, Poland.
FAU - Markiewicz-Zukowska, Renata
AU  - Markiewicz-Zukowska R
AD  - Department of Bromatology, Medical University, Bialystok, Poland.
FAU - Chlosta, Piotr
AU  - Chlosta P
AD  - Department of Urology, Medical College, Jagiellonian University, Krakow, Poland.
FAU - Borawska, Maria
AU  - Borawska M
AD  - Department of Urology, Medical College, Jagiellonian University, Krakow, Poland.
LA  - eng
PT  - Journal Article
DEP - 20170511
PL  - Poland
TA  - Ann Agric Environ Med
JT  - Annals of agricultural and environmental medicine : AAEM
JID - 9500166
RN  - 0R0008Q3JB (Chromium)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Carcinoma/blood/*metabolism/pathology
MH  - Chromium/blood/*metabolism
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - Urinary Bladder/metabolism
MH  - Urinary Bladder Neoplasms/blood/*metabolism/pathology
OTO - NOTNLM
OT  - bladder cancer
OT  - chromium
OT  - heavy metals
EDAT- 2017/12/30 06:00
MHDA- 2018/01/06 06:00
CRDT- 2017/12/30 06:00
PHST- 2017/12/30 06:00 [entrez]
PHST- 2017/12/30 06:00 [pubmed]
PHST- 2018/01/06 06:00 [medline]
AID - 72576 [pii]
AID - 10.5604/12321966.1232760 [doi]
PST - ppublish
SO  - Ann Agric Environ Med. 2017 Dec 23;24(4):602-605. doi: 10.5604/12321966.1232760. 
      Epub 2017 May 11.