PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Presence of histopathological premalignant lesions and infection caused by high-risk genotypes of human papillomavirus in patients with suspicious cytological and colposcopy results: A prospective study.

Abstract In patients with premalignant cervical lesions, human papillomavirus (HPV) infection, at any moment, may be spontaneously eliminated, or may persist or transform cervical epithelium from a lower to a higher degree. Due to that, it is necessary to wisely select the patients who are at high risk of cancer development. The aim of the study was to establish the interdependence between a suspicious Papanicolaou (Pap) test and colposcopy with the infection caused by high-risk genotypes of human papillomavirus and the presence of premalignant cervical lesions.
PMID
Related Publications

Correlation between atypical colposcopy findings and detection of human papillomavirus (HPV) infection of the uterine cervix.

Is human papillomavirus testing an effective triage method for detection of high-grade (grade 2 or 3) cervical intraepithelial neoplasia?

Reflex Human Papillomavirus Test Results as an Option for the Management of Korean Women With Atypical Squamous Cells Cannot Exclude High-Grade Squamous Intraepithelial Lesion.

Human papillomavirus and Papanicolaou tests to screen for cervical cancer.

Human papillomavirus testing as triage for atypical squamous cells of undetermined significance and low-grade squamous intraepithelial lesions: sensitivity, specificity, and cost-effectiveness.

Authors

Mayor MeshTerms
Keywords
Journal Title vojnosanitetski pregled
Publication Year Start




PMID- 29350503
OWN - NLM
STAT- In-Process
LR  - 20180130
IS  - 0042-8450 (Print)
IS  - 0042-8450 (Linking)
VI  - 74
IP  - 1
DP  - 2017 Jan
TI  - Presence of histopathological premalignant lesions and infection caused by
      high-risk genotypes of human papillomavirus in patients with suspicious
      cytological and colposcopy results: A prospective study.
PG  - 24-30
LID - 10.2298/VSP150205143G [doi]
AB  - Background/Aim: In patients with premalignant cervical lesions, human
      papillomavirus (HPV) infection, at any moment, may be spontaneously eliminated,
      or may persist or transform cervical epithelium from a lower to a higher degree. 
      Due to that, it is necessary to wisely select the patients who are at high risk
      of cancer development. The aim of the study was to establish the interdependence 
      between a suspicious Papanicolaou (Pap) test and colposcopy with the infection
      caused by high-risk genotypes of human papillomavirus and the presence of
      premalignant cervical lesions. Methods: This prospective study used cytological, 
      colposcopy, real-time polymerase chain reaction (PCR) of high-risk genotypes of
      human papillomavirus and histopathological analysis of cervical biopsy specimen. 
      Out of 2,578 female patients sent to cytological analyses in Clinical Center of
      Montenegro, during 2012, 2013 and 2014, the study included 80 women who had to
      submit their biopsy specimens due to a suspicious Pap test and atypical
      colposcopy results. Results: In the group of 80 (3.1%; n = 80/2,578) of the
      selected female patients with suspicious Pap test and colposcopy, 2/3 or 56 (70%)
      of them had cervicitis, and 1/3 or 24 (30%) had cervical intraepithelial
      neoplasia. The most common type in cervical intraepithelial neoplasia was HPV16
      in 8 female patients, ie 61.53% out of the number of infected, or 33.33% out of
      the total number of premalignant lesions Conclusion: Patients with suspicious
      Papanicolaou test, colposcopy results and infection which is caused by high-risk 
      HPV infection (HPV 16 in particular) often have premalignant cervical lesions. In
      these cases, histopathological confirmation of lesions is mandatory, since it
      serves as a definitive diagnostic procedure.
FAU - Golubovic, Mileta
AU  - Golubovic M
FAU - Lopicic, Milena
AU  - Lopicic M
FAU - Terzic, Natasa
AU  - Terzic N
FAU - Durovic, Marija
AU  - Durovic M
FAU - Mugosa, Boban
AU  - Mugosa B
FAU - Mijovic, Gordana
AU  - Mijovic G
LA  - eng
PT  - Journal Article
PL  - Serbia
TA  - Vojnosanit Pregl
JT  - Vojnosanitetski pregled
JID - 21530700R
EDAT- 2018/01/20 06:00
MHDA- 2018/01/20 06:00
CRDT- 2018/01/20 06:00
PHST- 2018/01/20 06:00 [pubmed]
PHST- 2018/01/20 06:00 [medline]
PHST- 2018/01/20 06:00 [entrez]
PST - ppublish
SO  - Vojnosanit Pregl. 2017 Jan;74(1):24-30.