PubTransformer

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PMID- 29381943
OWN - NLM
STAT- MEDLINE
DCOM- 20180208
LR  - 20180208
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 47
DP  - 2017 Nov
TI  - Acute myeloid leukemia presenting as erythema nodosum: A case report.
PG  - e8666
LID - 10.1097/MD.0000000000008666 [doi]
AB  - RATIONALE: Erythema nodosum (EN), a type of septal panniculitis, could be a rare 
      nonspecific cutaneous presentation of acute myeloid leukemia (AML). PATIENT
      CONCERNS: A 58-year-old Chinese female was admitted for a 4-week history of
      painful cutaneous lesions, accompanied by a sternal pain and fever. The lesions
      once resolved spontaneously but then recurred. Physical examination revealed
      warm, tender, indurated, rounded, erythematous to violaceous nodules in bilateral
      lower extremities, ranging in diameter from 1 to 6 cm. Blood marrow examination
      was compatible with AML-M2. DIAGNOSES: AML-M2 presenting as EN. INTERVENTIONS:
      Daunorubicin and cytarabine were used in induction chemotherapy. The patient
      achieved complete remission and her skin lesions disappeared simultaneously. Six 
      courses of consolidation chemotherapy were conducted in the following 6 months.
      OUTCOMES: The patient died due to AML relapse. LESSONS: The case strengthens the 
      awareness of cutaneous involvement of AML and raises oncological vigilance in
      patients with EN.
CI  - Copyright (c) 2017 The Authors. Published by Wolters Kluwer Health, Inc. All
      rights reserved.
FAU - Xu, Xiaohan
AU  - Xu X
AD  - Department of Anesthesiology.
FAU - Liang, Guangyu
AU  - Liang G
AD  - Department of Hematology, Peking Union Medical College Hospital, Chinese Academy 
      of Medical Sciences & Peking Union Medical College, Beijing, China.
FAU - Duan, Minghui
AU  - Duan M
AD  - Department of Hematology, Peking Union Medical College Hospital, Chinese Academy 
      of Medical Sciences & Peking Union Medical College, Beijing, China.
FAU - Zhang, Lu
AU  - Zhang L
AD  - Department of Hematology, Peking Union Medical College Hospital, Chinese Academy 
      of Medical Sciences & Peking Union Medical College, Beijing, China.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Antineoplastic Agents)
RN  - 04079A1RDZ (Cytarabine)
RN  - ZS7284E0ZP (Daunorubicin)
SB  - AIM
SB  - IM
MH  - Antineoplastic Agents/administration & dosage
MH  - Bone Marrow Examination/methods
MH  - Cytarabine/*administration & dosage
MH  - Daunorubicin/*administration & dosage
MH  - *Erythema Nodosum/diagnosis/etiology
MH  - Fatal Outcome
MH  - Female
MH  - Humans
MH  - Induction Chemotherapy/methods
MH  - *Leukemia, Myeloid, Acute/complications/diagnosis/physiopathology
MH  - Middle Aged
MH  - Recurrence
MH  - Remission Induction/methods
PMC - PMC5708942
EDAT- 2018/02/01 06:00
MHDA- 2018/02/09 06:00
CRDT- 2018/02/01 06:00
PHST- 2018/02/01 06:00 [entrez]
PHST- 2018/02/01 06:00 [pubmed]
PHST- 2018/02/09 06:00 [medline]
AID - 10.1097/MD.0000000000008666 [doi]
AID - 00005792-201711270-00034 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Nov;96(47):e8666. doi: 10.1097/MD.0000000000008666.