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Intrahepatic splenosis mimics hepatocellular carcinoma in a patient with chronic hepatitis B: A case report and literature review.

Abstract Splenosis is a benign and relatively uncommon condition caused by trauma or splenectomy or other procedures involving splenic tissue. It is usually asymptomatic, and often diagnosed accidentally, especially misdiagnosed as malignant tumor.
PMID
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Authors

Mayor MeshTerms

Liver

Splenosis

Keywords
Journal Title medicine
Publication Year Start




PMID- 29381947
OWN - NLM
STAT- MEDLINE
DCOM- 20180208
LR  - 20180208
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 47
DP  - 2017 Nov
TI  - Intrahepatic splenosis mimics hepatocellular carcinoma in a patient with chronic 
      hepatitis B: A case report and literature review.
PG  - e8680
LID - 10.1097/MD.0000000000008680 [doi]
AB  - BACKGROUND: Splenosis is a benign and relatively uncommon condition caused by
      trauma or splenectomy or other procedures involving splenic tissue. It is usually
      asymptomatic, and often diagnosed accidentally, especially misdiagnosed as
      malignant tumor. METHODS: A 54-year-old man with prior history of chronic
      hepatitis B virus infection and underwent splenectomy for traumatic splenic
      rupture following a traffic accident 23 years previously was admitted to our
      hospital and found a hepatic mass in the right upper quadrant during an imaging
      examination. The diagnosis of his was not clear and finally he agreed to receive 
      a surgical treatment. RESULTS: During the operation, we found a mass in the right
      posterior lobe of the liver and a hard nodule on the right side of the diaphragm,
      both were completely resected, and postoperative histopathologic examination
      revealed that all excised tissues were proved to have histological structure
      typical for the spleen. CONCLUSIONS: The occurrence of intrahepatic splenosis is 
      rare with only few cases previously reported in the literature. It is a benign
      disease and sometimes difficult to distinguish from diseases of the liver. The
      need for positive surgical resection of splenosis is still controversial.
CI  - Copyright (c) 2017 The Authors. Published by Wolters Kluwer Health, Inc. All
      rights reserved.
FAU - Wang, Wen-Chao
AU  - Wang WC
AD  - Department of Hepatic Surgery IV, The Eastern Hepatobiliary Surgery Hospital,
      Second Military Medical University.
AD  - Yangpu Hospital, Tongji University School of Medicine, Shanghai, China.
FAU - Li, Xi-Feng
AU  - Li XF
AD  - Department of Hepatic Surgery IV, The Eastern Hepatobiliary Surgery Hospital,
      Second Military Medical University.
FAU - Yan, Zhen-Lin
AU  - Yan ZL
AD  - Department of Hepatic Surgery IV, The Eastern Hepatobiliary Surgery Hospital,
      Second Military Medical University.
FAU - Wang, Yu
AU  - Wang Y
AD  - Department of Hepatic Surgery IV, The Eastern Hepatobiliary Surgery Hospital,
      Second Military Medical University.
FAU - Ma, Jun-Yong
AU  - Ma JY
AD  - Department of Hepatic Surgery IV, The Eastern Hepatobiliary Surgery Hospital,
      Second Military Medical University.
FAU - Shi, Le-Hua
AU  - Shi LH
AD  - Department of Hepatic Surgery IV, The Eastern Hepatobiliary Surgery Hospital,
      Second Military Medical University.
FAU - Zhang, Xiao-Feng
AU  - Zhang XF
AD  - Department of Hepatic Surgery IV, The Eastern Hepatobiliary Surgery Hospital,
      Second Military Medical University.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - AIM
SB  - IM
MH  - Accidents, Traffic
MH  - Carcinoma, Hepatocellular/*diagnosis
MH  - Hepatectomy/methods
MH  - Humans
MH  - Incidental Findings
MH  - *Liver/diagnostic imaging/pathology/surgery
MH  - Liver Neoplasms/*diagnosis
MH  - Male
MH  - Middle Aged
MH  - Splenectomy/*adverse effects/methods
MH  - Splenic Rupture/*surgery
MH  - *Splenosis/diagnosis/etiology/physiopathology/surgery
PMC - PMC5708946
EDAT- 2018/02/01 06:00
MHDA- 2018/02/09 06:00
CRDT- 2018/02/01 06:00
PHST- 2018/02/01 06:00 [entrez]
PHST- 2018/02/01 06:00 [pubmed]
PHST- 2018/02/09 06:00 [medline]
AID - 10.1097/MD.0000000000008680 [doi]
AID - 00005792-201711270-00038 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Nov;96(47):e8680. doi: 10.1097/MD.0000000000008680.