PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Acute appendicitis complicated with necrotizing fasciitis in a patient with adult-onset Still's disease: A case report.

Abstract Adult-onset Still disease (AOSD) is a rare systemic inflammatory disease of unknown etiology characterized by evanescent salmon-pink rash, spiking fever, arthralgia/ arthritis, and lymphadenopathy. AOSD sometimes was fatal when it is complicated by macrophage activation syndrome (MAS) or hemophagocytic lymphohistiocytosis (HLH). Nonetheless, the literature provides no recommendations for treatment of AOSD patients with severe sepsis.
PMID
Related Publications

Macrophage activation syndrome complicating adult onset Still's disease: A single center case series and comparison with literature.

Necrotizing fasciitis caused by perforated appendicitis: a case report.

Clinical characteristics and follow-up analysis of adult-onset Still's disease complicated by hemophagocytic lymphohistiocytosis.

A case of adult onset Still's disease with systemic inflammatory response syndrome complicated by fatal status epilepticus.

Tocilizumab for uncontrollable systemic inflammatory response syndrome complicating adult-onset Still disease: Case report and review of literature.

Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 29384877
OWN - NLM
STAT- MEDLINE
DCOM- 20180209
LR  - 20180209
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 5
DP  - 2018 Feb
TI  - Acute appendicitis complicated with necrotizing fasciitis in a patient with
      adult-onset Still's disease: A case report.
PG  - e9794
LID - 10.1097/MD.0000000000009794 [doi]
AB  - RATIONALE: Adult-onset Still disease (AOSD) is a rare systemic inflammatory
      disease of unknown etiology characterized by evanescent salmon-pink rash, spiking
      fever, arthralgia/ arthritis, and lymphadenopathy. AOSD sometimes was fatal when 
      it is complicated by macrophage activation syndrome (MAS) or hemophagocytic
      lymphohistiocytosis (HLH). Nonetheless, the literature provides no
      recommendations for treatment of AOSD patients with severe sepsis. PATIENT
      CONCERNS: A previously healthy 65-year-old man with history of AOSD was referred 
      to our hospital for persistent right lower quadrant abdominal pain for 2 days.
      One week later, an abdominal wall abscess and hematoma developed by extravasation
      from the inferior epigastric vessels, complicated by necrotizing fasciitis of the
      right thigh and groin region. To our best knowledge, this case was the first
      reported case of a perforated appendix complicated with necrotizing fasciitis in 
      a patient with AOSD. DIAGNOSES: The patient was diagnosed as acute appendicitis
      complicated with necrotizing fasciitis and abdominal wall abscess. INTERVENTIONS:
      This case received intravenous tigecycline injection and daily 10 mg prednisolone
      initially, and shifted to daily intravenous hydrocortisone 200 mg for suspected
      MAS or HLH. This patient underwent surgical intervention and debridement for
      necrotizing fasciitis. OUTCOMES: The patient's symptoms progressed worse rapidly.
      He died from cytomegalovirus viremia and bacterial necrotizing fasciitis
      complicated by septic shock. LESSONS: (1) The steroid dose was difficult to
      titrate when AOSD complicated by sepsis. The differential diagnosis from MAS/HLH 
      with bacterial/viral infection related severe sepsis was difficult but critical
      for decision making from clinicians and rheumatologists. (2) The conservative
      treatment with antibiotics for perforated appendix is safe but has a higher
      failure rate in immunocomprised patients such as systemic lupus erythematosus and
      AOSD. Early surgical intervention might contribute to better outcome. (3) The
      abdominal wall abscess can be spread from intra-abdominal lesion through the
      inferior epigastric vessels which were as weak points of abdominal wall. Imaging 
      examinations contribute to acute diagnosis and help surgeons perform surgical
      interventions to prevent morbidity and mortality.
FAU - Huang, Zheng-Hao
AU  - Huang ZH
AD  - Division of Rheumatology/Immunology and Allergy, Department of Internal Medicine,
      Tri-Service General Hospital.
AD  - Division of Rheumatology/Immunology and Allergy, Department of Medicine,
      Kaohsiung Armed Forces General Hospital, Kaohsiung.
FAU - Chiu, Yu-Chen
AU  - Chiu YC
AD  - Division of General Surgery, Department of Surgery.
FAU - Ho, Li-Lu
AU  - Ho LL
AD  - Department of Internal Medicine, Tri-Service General Hospital, National Defense
      Medical Center, Taipei, Taiwan.
FAU - Fan, Hsiu-Lung
AU  - Fan HL
AD  - Division of General Surgery, Department of Surgery.
FAU - Lu, Chun-Chi
AU  - Lu CC
AD  - Division of Rheumatology/Immunology and Allergy, Department of Internal Medicine,
      Tri-Service General Hospital.
AD  - Department of Pathology, University of Washington, Seattle, WA, USA.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - AIM
SB  - IM
MH  - Aged
MH  - Appendicitis/*etiology
MH  - Fasciitis, Necrotizing/*etiology
MH  - Fatal Outcome
MH  - Humans
MH  - Male
MH  - Shock, Septic/*etiology
MH  - Still's Disease, Adult-Onset/*complications/therapy
EDAT- 2018/02/01 06:00
MHDA- 2018/02/10 06:00
CRDT- 2018/02/01 06:00
PHST- 2018/02/01 06:00 [entrez]
PHST- 2018/02/01 06:00 [pubmed]
PHST- 2018/02/10 06:00 [medline]
AID - 10.1097/MD.0000000000009794 [doi]
AID - 00005792-201802020-00039 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2018 Feb;97(5):e9794. doi: 10.1097/MD.0000000000009794.