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Multiple Chemical Sensitivity (MCS): History, Epidemiology and Mechanism.

Abstract Multiple chemical sensitivity (MCS), also known as idiopathic environmental intolerance, has been described as a chronic acquired disorder characterized by nonspecific symptoms in multiple organ systems and is associated with exposure to low-level chemicals. The name was established by Cullen, in 1987, although the name and diagnostic criteria are still under debate even now. A number of hypotheses concering the etiology and pathogenesis of MCS have been proposed, including impairmens of neurological, immunological and psychological systems. However, research on the possible mechanisms underlying MCS is far from complete. The name and diagnostic criteria of its history as well as theoretical and experimental mechanisms underlying MCS are reviewed here.
PMID
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Authors

Mayor MeshTerms
Keywords

criteria

epidemiology

history

mechanism

multple chemical sensitivity

Journal Title nihon eiseigaku zasshi. japanese journal of hygiene
Publication Year Start




PMID- 29386440
OWN - NLM
STAT- MEDLINE
DCOM- 20180228
LR  - 20180228
IS  - 1882-6482 (Electronic)
IS  - 0021-5082 (Linking)
VI  - 73
IP  - 1
DP  - 2018
TI  - [Multiple Chemical Sensitivity (MCS): History, Epidemiology and Mechanism].
PG  - 1-8
LID - 10.1265/jjh.73.1 [doi]
AB  - Multiple chemical sensitivity (MCS), also known as idiopathic environmental
      intolerance, has been described as a chronic acquired disorder characterized by
      nonspecific symptoms in multiple organ systems and is associated with exposure to
      low-level chemicals. The name was established by Cullen, in 1987, although the
      name and diagnostic criteria are still under debate even now. A number of
      hypotheses concering the etiology and pathogenesis of MCS have been proposed,
      including impairmens of neurological, immunological and psychological systems.
      However, research on the possible mechanisms underlying MCS is far from complete.
      The name and diagnostic criteria of its history as well as theoretical and
      experimental mechanisms underlying MCS are reviewed here.
FAU - Katoh, Takahiko
AU  - Katoh T
AD  - Department of Public Health, Faculty of Life Sciences, Kumamoto University.
LA  - jpn
PT  - Historical Article
PT  - Journal Article
PT  - Review
PL  - Japan
TA  - Nihon Eiseigaku Zasshi
JT  - Nihon eiseigaku zasshi. Japanese journal of hygiene
JID - 0417457
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Environmental Exposure/*adverse effects
MH  - Environmental Pollution/*adverse effects
MH  - Female
MH  - History, 20th Century
MH  - History, 21st Century
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multiple Chemical Sensitivity/diagnosis/epidemiology/*etiology/history
MH  - Young Adult
OTO - NOTNLM
OT  - criteria
OT  - epidemiology
OT  - history
OT  - mechanism
OT  - multple chemical sensitivity
EDAT- 2018/02/02 06:00
MHDA- 2018/03/01 06:00
CRDT- 2018/02/02 06:00
PHST- 2018/02/02 06:00 [entrez]
PHST- 2018/02/02 06:00 [pubmed]
PHST- 2018/03/01 06:00 [medline]
AID - 10.1265/jjh.73.1 [doi]
PST - ppublish
SO  - Nihon Eiseigaku Zasshi. 2018;73(1):1-8. doi: 10.1265/jjh.73.1.