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Clinical and pathology analysis of 1 case of adult pleural pulmonary blastoma: A case report.

Abstract Pulmonary blastoma is a rare primary lung cancer that can be categorized into adult type and child type. The clinical symptoms and imaging features of pulmonary blastoma are nonspecific, making it difficult to diagnose preoperatively. Postoperative pathology with immunohistochemical staining can help diagnosis.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 29390280
OWN - NLM
STAT- In-Process
LR  - 20180202
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 50
DP  - 2017 Dec
TI  - Clinical and pathology analysis of 1 case of adult pleural pulmonary blastoma: A 
      case report.
PG  - e8918
LID - 10.1097/MD.0000000000008918 [doi]
AB  - RATIONALE: Pulmonary blastoma is a rare primary lung cancer that can be
      categorized into adult type and child type. The clinical symptoms and imaging
      features of pulmonary blastoma are nonspecific, making it difficult to diagnose
      preoperatively. Postoperative pathology with immunohistochemical staining can
      help diagnosis. PATIENT CONCERNS: A 53-year-old male had chest tightness and
      shortness of breath. DIAGNOSES: The patient was diagnosed as pleural pulmonary
      blastoma based on computed tomography (CT) scan, pathology, immunohistochemistry,
      and molecular pathology. CT examination showed solid mass on the upper lobe of
      the left lung Intraoperative observation found that tumor tissue was gray with
      tough texture. The surrounding lung tissue showed AE1/AE3 (+), Vimentin (+), and 
      CD34 (+) staining. No epidermal growth factor receptor gene mutation was
      detected. INTERVENTIONS: The left lobe resection plus mediastinal lymph node
      dissection were performed. After the operation, patient received paclitaxel
      combined with nedaplatin chemotherapy for 4 times. OUTCOMES: Four months later,
      left pleural metastasis, and mediastinal lymph node metastasis was found. The
      patient died 15 months later. LESSONS: Pleural pulmonary blastoma is a malignant 
      tumor with rare pathological features that is easy to relapse and metastasis with
      poor prognosis. Surgical treatment preferably, lobectomy plus mediastinal lymph
      node dissection, is the first treatment option. The overall prognosis is poor.
CI  - Copyright (c) 2017 The Authors. Published by Wolters Kluwer Health, Inc. All
      rights reserved.
FAU - Liu, Yi
AU  - Liu Y
AD  - Department of Thoracic Surgery, Xinjiang Medical University Affiliated Tumor
      Hospital, Urumqi, Xinjiang.
FAU - Luo, Dongbo
AU  - Luo D
FAU - Du, Tongxin
AU  - Du T
FAU - Wang, Hongjiang
AU  - Wang H
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
EDAT- 2018/02/03 06:00
MHDA- 2018/02/03 06:00
CRDT- 2018/02/03 06:00
PHST- 2018/02/03 06:00 [entrez]
PHST- 2018/02/03 06:00 [pubmed]
PHST- 2018/02/03 06:00 [medline]
AID - 10.1097/MD.0000000000008918 [doi]
AID - 00005792-201712150-00030 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Dec;96(50):e8918. doi: 10.1097/MD.0000000000008918.