Contrast-enhanced ultrasound diagnosis of hepatic metastasis of concurrent medullary-papillary thyroid carcinoma: A case report.
|Abstract||Co-occurrence of medullary thyroid carcinoma (MTC) and papillary thyroid carcinoma (PTC) in the same thyroid gland with liver metastasis is a rare condition. To our knowledge, the utility of contrast-enhanced ultrasound (CEUS) to diagnose it is much less.|
Robot-assisted Sistrunk's operation, total thyroidectomy, and neck dissection via a transaxillary and retroauricular (TARA) approach in papillary carcinoma arising in thyroglossal duct cyst and thyroid gland.
|Publication Year Start||2018-01-01|
PMID- 29390301 OWN - NLM STAT- MEDLINE DCOM- 20180212 LR - 20180212 IS - 1536-5964 (Electronic) IS - 0025-7974 (Linking) VI - 96 IP - 50 DP - 2017 Dec TI - Contrast-enhanced ultrasound diagnosis of hepatic metastasis of concurrent medullary-papillary thyroid carcinoma: A case report. PG - e9065 LID - 10.1097/MD.0000000000009065 [doi] AB - RATIONALE: Co-occurrence of medullary thyroid carcinoma (MTC) and papillary thyroid carcinoma (PTC) in the same thyroid gland with liver metastasis is a rare condition. To our knowledge, the utility of contrast-enhanced ultrasound (CEUS) to diagnose it is much less. PATIENT CONCERNS: A 33-year-old female was referred to our hospital due to the increase in plasma calcitonin concentration and carcino-embryonic antigen 12 months after her total thyroidectomy. To find metastasis, she received laboratory tests, gray-scale US, and CEUS. In our paper, ethical approval was not necessary, as this article is a case report, which is based on the clinical information of the patient. Because our case does not refer to the patient's privacy, informed consent is not necessary. DIAGNOSES: Gray-scale abdominal ultrasound image demonstrated a mildly hyperechoic nodule in the liver. In CEUS, the nodules were hyperenhanced in the arterial phase. In the late arterial phase, the enhancement was washed out quickly. The nodules presented hypoenhancement in the portal and parenchymal phase, which conformed to the hepatic metastasis. INTERVENTIONS: The patient received thyroid and liver surgery. OUTCOMES: She was free of disease for 10 months at the time of this report. LESSONS: In this case, liver metastases from MTC can be detected and characterized reliably as hypoenhancing lesions during the portal venous and late phases of CEUS, washing out starts early, and is marked. We suspect MTC is a kind of tumor that tends to have rich blood supply and consider contrast-enhanced ultrasound as a suitable method for the follow-up of patients with MTC. CI - Copyright (c) 2017 The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved. FAU - Zhou, Jie AU - Zhou J AD - Department of Ultrasound. FAU - Luo, Yan AU - Luo Y AD - Department of Ultrasound. FAU - Ma, Bu Yun AU - Ma BY AD - Department of Ultrasound. FAU - Ling, Wen Wu AU - Ling WW AD - Department of Ultrasound. FAU - Zhu, Xiang Lan AU - Zhu XL AD - Department of Pathology, The West China Hospital of Sichuan University, Chengdu, China. LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Medicine (Baltimore) JT - Medicine JID - 2985248R RN - 0 (Contrast Media) RN - 0 (Phospholipids) RN - 0 (contrast agent BR1) RN - WS7LR3I1D6 (Sulfur Hexafluoride) RN - Thyroid cancer, medullary RN - Thyroid cancer, papillary SB - AIM SB - IM MH - Adult MH - Carcinoma, Neuroendocrine/*pathology/surgery MH - Carcinoma, Papillary/*pathology/surgery MH - Contrast Media MH - Diagnosis, Differential MH - Female MH - Humans MH - Liver Neoplasms/*diagnostic imaging/*secondary/surgery MH - Phospholipids MH - Sulfur Hexafluoride MH - Thyroid Neoplasms/*pathology/surgery MH - Thyroidectomy MH - Ultrasonography/*methods EDAT- 2018/02/03 06:00 MHDA- 2018/02/13 06:00 CRDT- 2018/02/03 06:00 PHST- 2018/02/03 06:00 [entrez] PHST- 2018/02/03 06:00 [pubmed] PHST- 2018/02/13 06:00 [medline] AID - 10.1097/MD.0000000000009065 [doi] AID - 00005792-201712150-00051 [pii] PST - ppublish SO - Medicine (Baltimore). 2017 Dec;96(50):e9065. doi: 10.1097/MD.0000000000009065.