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Primary Sjögren syndrome that initially presented with repeated hypergammaglobulinemic purpura after prolonged sitting: A case report.

Abstract Purpura is a common dermatologic manifestation in Sjögren syndrome (SS). When a patient presents with sicca symptoms, the diagnosis of SS is not difficult.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 29390329
OWN - NLM
STAT- MEDLINE
DCOM- 20180213
LR  - 20180213
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 50
DP  - 2017 Dec
TI  - Primary Sjogren syndrome that initially presented with repeated
      hypergammaglobulinemic purpura after prolonged sitting: A case report.
PG  - e9187
LID - 10.1097/MD.0000000000009187 [doi]
AB  - RATIONALE: Purpura is a common dermatologic manifestation in Sjogren syndrome
      (SS). When a patient presents with sicca symptoms, the diagnosis of SS is not
      difficult. PATIENT CONCERNS: Here, we reported a case of a 52-year-old Chinese
      woman who initially presented with nonpalpable purpura on both lower extremities,
      and these lesions had developed soon after prolonged sitting. In the past 2
      years, she had repeated cutaneous nonpalpable purpura 4 times. She had no sicca
      symptoms, dry eyes, or dry mouth. DIAGNOSES: Combining the laboratory findings,
      Schirmer test, and labial gland biopsy, primary SS was confirmed. INTERVENTIONS: 
      The patient was placed on a trial of hydroxychloroquine (200 mg once daily).
      OUTCOMES: The purpura on both lower extremities had faded at the sixth day after 
      onset and at the third day after hydroxychloroquine treatment. LESSONS: These
      case was not easy to diagnosis primary SS because she had no sicca symptoms. A
      patient with primary SS who initially presented with recurrent purpura associated
      with prolonged sitting. Prolonged sitting had been a possible aggravating factor 
      for the cutaneous purpura of this patient with primary SS.
CI  - Copyright (c) 2017 The Authors. Published by Wolters Kluwer Health, Inc. All
      rights reserved.
FAU - Zhou, Zhihua
AU  - Zhou Z
FAU - Jiang, Weiqiang
AU  - Jiang W
FAU - Wang, Ming
AU  - Wang M
FAU - Liu, Yongyuan
AU  - Liu Y
FAU - Zhang, Wei
AU  - Zhang W
FAU - Huang, Manping
AU  - Huang M
FAU - Liang, Donghui
AU  - Liang D
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Antirheumatic Agents)
RN  - 4QWG6N8QKH (Hydroxychloroquine)
SB  - AIM
SB  - IM
MH  - Antirheumatic Agents/*therapeutic use
MH  - Female
MH  - Humans
MH  - Hydroxychloroquine/*therapeutic use
MH  - Hypergammaglobulinemia/*diagnosis/*drug therapy
MH  - Lower Extremity
MH  - Middle Aged
MH  - Posture
MH  - Purpura/*diagnosis/*drug therapy
MH  - Sjogren's Syndrome/*diagnosis/*drug therapy
EDAT- 2018/02/03 06:00
MHDA- 2018/02/14 06:00
CRDT- 2018/02/03 06:00
PHST- 2018/02/03 06:00 [entrez]
PHST- 2018/02/03 06:00 [pubmed]
PHST- 2018/02/14 06:00 [medline]
AID - 10.1097/MD.0000000000009187 [doi]
AID - 00005792-201712150-00079 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Dec;96(50):e9187. doi: 10.1097/MD.0000000000009187.