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Chinese herbal medicine for patients with atrial fibrillation: protocol for a systematic review and meta-analysis.

Abstract Atrial fibrillation (AF) is the most clinically common cardiac arrhythmia. Chinese herbal medicine (CHM) has been widely applied in the treatment of AF, However, to our knowledge, there has been no systematic review and meta-analysis of randomized controlled trails (RCTs) regarding the effectiveness of this treatment. Therefore, we provide a protocol to evaluate the effectiveness and safety of CHM for AF.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 29390351
OWN - NLM
STAT- MEDLINE
DCOM- 20180212
LR  - 20180212
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 50
DP  - 2017 Dec
TI  - Chinese herbal medicine for patients with atrial fibrillation: protocol for a
      systematic review and meta-analysis.
PG  - e9228
LID - 10.1097/MD.0000000000009228 [doi]
AB  - BACKGROUND: Atrial fibrillation (AF) is the most clinically common cardiac
      arrhythmia. Chinese herbal medicine (CHM) has been widely applied in the
      treatment of AF, However, to our knowledge, there has been no systematic review
      and meta-analysis of randomized controlled trails (RCTs) regarding the
      effectiveness of this treatment. Therefore, we provide a protocol to evaluate the
      effectiveness and safety of CHM for AF. METHODS: The databases reviewed to
      collect RCTs related to CHM treatment for AF will be as follows: 3 English
      literature databases, which are PubMed, Embase, and Cochrane Library, and 3
      Chinese literature databases, which are CBM, CNKI, and Wanfang. The data
      collection in the above-mentioned databases will be from the time when the
      respective databases were established to December 2017. The maintenance of sinus 
      rhythm and p-wave dispersion will be accepted as the primary outcomes. Quality of
      life (QOL), such as QOL scale embolic events, bleeding events, and symptom
      improvement (such as chest distress, palpitations, etc) will be measured as
      secondary outcomes. Two reviewers will independently screen the titles,
      abstracts, or even full texts, and extract data. Methodological quality will be
      evaluated according to the Cochrane risk of bias. All analyses will be applied by
      RevMan (version 5.3). RESULTS: The results of study will be disseminated via both
      international conference and peer-review journal. CONCLUSION: The conclusion of
      our systematic review will provide evidence to judge whether CHM is an effective 
      intervention for patient with AF.
CI  - Copyright (c) 2017 The Authors. Published by Wolters Kluwer Health, Inc. All
      rights reserved.
FAU - Cai, Xiaoli
AU  - Cai X
AD  - Guangzhou University of Chinese Medicine.
FAU - Wang, Yuanping
AU  - Wang Y
AD  - Guangzhou University of Chinese Medicine.
FAU - Li, Ziqing
AU  - Li Z
AD  - Guangzhou University of Chinese Medicine.
FAU - Zhang, Yu
AU  - Zhang Y
AD  - Guangzhou University of Chinese Medicine.
FAU - Wang, Dawei
AU  - Wang D
AD  - The Second Affiliated Hospital of Guangzhou University of Chinese Medicine,
      Guangdong Provincial Hospital of Chinese Medicine.
AD  - Guangdong Provincial Key Laboratory of Research on Emergency in TCM, Guangzhou,
      China.
FAU - Yan, Xia
AU  - Yan X
AD  - The Second Affiliated Hospital of Guangzhou University of Chinese Medicine,
      Guangdong Provincial Hospital of Chinese Medicine.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Drugs, Chinese Herbal)
SB  - AIM
SB  - IM
MH  - Atrial Fibrillation/*drug therapy
MH  - Drugs, Chinese Herbal/*therapeutic use
MH  - Humans
MH  - Research Design
EDAT- 2018/02/03 06:00
MHDA- 2018/02/13 06:00
CRDT- 2018/02/03 06:00
PHST- 2018/02/03 06:00 [entrez]
PHST- 2018/02/03 06:00 [pubmed]
PHST- 2018/02/13 06:00 [medline]
AID - 10.1097/MD.0000000000009228 [doi]
AID - 00005792-201712150-00101 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Dec;96(50):e9228. doi: 10.1097/MD.0000000000009228.