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Treatment-related acute granulocyte-monocytic leukemia from multiple myeloma: A case report and literature review.

Abstract To investigate the clinical features of treatment-related acute granulocyte-monocytic leukemia (t-AML) from multiple myeloma (MM) thereby improving the understanding of this disease.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 29390389
OWN - NLM
STAT- MEDLINE
DCOM- 20180212
LR  - 20180212
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 50
DP  - 2017 Dec
TI  - Treatment-related acute granulocyte-monocytic leukemia from multiple myeloma: A
      case report and literature review.
PG  - e9293
LID - 10.1097/MD.0000000000009293 [doi]
AB  - RATIONALE: To investigate the clinical features of treatment-related acute
      granulocyte-monocytic leukemia (t-AML) from multiple myeloma (MM) thereby
      improving the understanding of this disease. PATIENT CONCERNS: A 72-year-old
      woman patient was initially diagnosed as MM. Two years and 7 months after
      treatment, this patient developed AML M4 as confirmed by the analyses from
      clinical features, bone marrow morphology, flow cytometry, and cytogenetic
      examination. DIAGNOSIS: Treatment-related acute myeloid leukaemia (t-AML).
      INTERVENTIONS: Due to lack of the ability to pay the cost, she declined our
      recommendation to accept therapy as an inpatient and was discharged. LESSONS: The
      reported case was a rare t-AML, which is resistant to currently available
      treatments and has a poor prognosis.
CI  - Copyright (c) 2017 The Authors. Published by Wolters Kluwer Health, Inc. All
      rights reserved.
FAU - Qian, Juan
AU  - Qian J
AD  - Department of Hematology, Affiliated Hospital of Nantong University, Nantong,
      Jiangsu, China.
FAU - Shi, Wenyu
AU  - Shi W
FAU - Yang, Li
AU  - Yang L
FAU - Lin, Zenghua
AU  - Lin Z
FAU - Cai, Yifeng
AU  - Cai Y
FAU - Liu, Hong
AU  - Liu H
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Antineoplastic Agents)
SB  - AIM
SB  - IM
MH  - Aged
MH  - Antineoplastic Agents/*adverse effects
MH  - Female
MH  - Flow Cytometry
MH  - Humans
MH  - Immunophenotyping
MH  - Leukemia, Monocytic, Acute/*chemically induced/pathology
MH  - Multiple Myeloma/*drug therapy/pathology
MH  - Neoplasm Staging
EDAT- 2018/02/03 06:00
MHDA- 2018/02/13 06:00
CRDT- 2018/02/03 06:00
PHST- 2018/02/03 06:00 [entrez]
PHST- 2018/02/03 06:00 [pubmed]
PHST- 2018/02/13 06:00 [medline]
AID - 10.1097/MD.0000000000009293 [doi]
AID - 00005792-201712150-00139 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Dec;96(50):e9293. doi: 10.1097/MD.0000000000009293.